Search Results - "Schmitz, Gavin P."

Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics by Jeong, Jae-Woong, McCall, Jordan G., Shin, Gunchul, Zhang, Yihui, Al-Hasani, Ream, Kim, Minku, Li, Shuo, Sim, Joo Yong, Jang, Kyung-In, Shi, Yan, Hong, Daniel Y., Liu, Yuhao, Schmitz, Gavin P., Xia, Li, He, Zhubin, Gamble, Paul, Ray, Wilson Z., Huang, Yonggang, Bruchas, Michael R., Rogers, John A.

“…In vivo pharmacology and optogenetics hold tremendous promise for dissection of neural circuits, cellular signaling, and manipulating neurophysiological…”
Get full text

In vivo detection of optically-evoked opioid peptide release by Al-Hasani, Ream, Wong, Jenny-Marie T, Mabrouk, Omar S, McCall, Jordan G, Schmitz, Gavin P, Porter-Stransky, Kirsten A, Aragona, Brandon J, Kennedy, Robert T, Bruchas, Michael R

“…Though the last decade has seen accelerated advances in techniques and technologies to perturb neuronal circuitry in the brain, we are still poorly equipped to…”
Get full text

G protein-coupled receptors as targets for transformative neuropsychiatric therapeutics by Schmitz, Gavin P, Roth, Bryan L

“…G protein-coupled receptors (GPCRs) constitute the largest family of druggable genes in the human genome. Even though perhaps 30% of approved medications…”
Get more information

Structures of the entire human opioid receptor family by Wang, Yue, Zhuang, Youwen, DiBerto, Jeffrey F., Zhou, X. Edward, Schmitz, Gavin P., Yuan, Qingning, Jain, Manish K., Liu, Weiyi, Melcher, Karsten, Jiang, Yi, Roth, Bryan L., Xu, H. Eric

“…Opioids are effective analgesics, but their use is beset by serious side effects, including addiction and respiratory depression, which contribute to the…”
Get full text

Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement by Al-Hasani, Ream, Gowrishankar, Raajaram, Schmitz, Gavin P., Pedersen, Christian E., Marcus, David J., Shirley, Sofia E., Hobbs, Taylor E., Elerding, Abigail J., Renaud, Sophie J., Jing, Miao, Li, Yulong, Alvarez, Veronica A., Lemos, Julia C., Bruchas, Michael R.

“…The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is relatively understudied, and therefore its role in…”
Get full text

Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward by Al-Hasani, Ream, McCall, Jordan G., Shin, Gunchul, Gomez, Adrian M., Schmitz, Gavin P., Bernardi, Julio M., Pyo, Chang-O., Park, Sung Il, Marcinkiewcz, Catherine M., Crowley, Nicole A., Krashes, Michael J., Lowell, Bradford B., Kash, Thomas L., Rogers, John A., Bruchas, Michael R.

“…The nucleus accumbens (NAc) and the dynorphinergic system are widely implicated in motivated behaviors. Prior studies have shown that activation of…”
Get full text

5‑HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics by Schmitz, Gavin P., Jain, Manish K., Slocum, Samuel T., Roth, Bryan L.

“…Serotonin (5-hydroxytryptamine; 5-HT) 2A receptor (5-HT2AR) signaling is essential for the actions of classical psychedelic drugs. In this study, we examined…”
Get full text

5-HT 2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics by Schmitz, Gavin P, Jain, Manish K, Slocum, Samuel T, Roth, Bryan L

“…Serotonin (5-hydroxytryptamine; 5-HT) 2A receptor (5-HT2AR) signaling is essential for the actions of classical psychedelic drugs. In this study, we examined…”
Get full text

Author Correction: Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement by Al-Hasani, Ream, Gowrishankar, Raajaram, Schmitz, Gavin P., Pedersen, Christian E., Marcus, David J., Shirley, Sofia E., Hobbs, Taylor E., Elerding, Abigail J., Renaud, Sophie J., Jing, Miao, Li, Yulong, Alvarez, Veronica A., Lemos, Julia C., Bruchas, Michael R.

Get full text

Ventral tegmental area GABAergic inhibition of ventral accumbens shell cholinergic interneurons promotes reward reinforcement by Al-Hasani, Ream, Gowrishankar, Raajaram, Schmitz, Gavin P., Pedersen, Christian E., Marcus, David J., Shirley, Sofia E., Hobbs, Taylor E., Elerding, Abigail J., Renaud, Sophie J., Jing, Miao, Li, Yulong, Alvarez, Veronica A., Lemos, Julia C., Bruchas, Michael R.

“…The functional role of long-range ventral tegmental area (VTA) to nucleus accumbens (NAc) GABAergic projections in regulating reward reinforcement remains…”
Get full text