Search Results - "Schmitt, Timothy"

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes by Xie, Yuchao, McGill, Mitchell R., Dorko, Kenneth, Kumer, Sean C., Schmitt, Timothy M., Forster, Jameson, Jaeschke, Hartmut

“…Acetaminophen (APAP) overdose is the most prevalent cause of drug-induced liver injury in western countries. Numerous studies have been conducted to…”
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Temporary placement of fully covered self-expandable metal stents in benign biliary strictures: midterm evaluation (with video) by Mahajan, Anshu, MD, Ho, Henry, MD, Sauer, Bryan, MD, MS, Phillips, Melissa S., MD, Shami, Vanessa M., MD, Ellen, Kristi, RN, Rehan, Michele, MS, Schmitt, Timothy M., MD, Kahaleh, Michel, MD, FASGE

“…Background Benign biliary strictures (BBS) have been endoscopically managed with placement of multiple plastic stents. Uncovered metal stents have been…”
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Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis by Woolbright, Benjamin L., Dorko, Kenneth, Antoine, Daniel J., Clarke, Joanna I., Gholami, Parviz, Li, Feng, Kumer, Sean C., Schmitt, Timothy M., Forster, Jameson, Fan, Fang, Jenkins, Rosalind E., Park, B. Kevin, Hagenbuch, Bruno, Olyaee, Mojtaba, Jaeschke, Hartmut

“…Accumulation of bile acids is a major mediator of cholestatic liver injury. Recent studies indicate bile acid composition between humans and rodents is…”
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Correlations of Long Noncoding RNA HNF4A-AS1 Alternative Transcripts with Liver Diseases and Drug Metabolism by Jin, Jing, Nguyen, Le Tra Giang, Wassef, Andrew, Sadek, Ragui, Schmitt, Timothy M, Guo, Grace L, Rasmussen, Theodore P, Zhong, Xiao-Bo

“…Hepatocyte nuclear factor 4 alpha antisense 1 ( ) is a long noncoding RNA (lncRNA) gene physically located next to the transcription factor gene in the human…”
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Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes by Xie, Yuchao, McGill, Mitchell R., Du, Kuo, Dorko, Kenneth, Kumer, Sean C., Schmitt, Timothy M., Ding, Wen-Xing, Jaeschke, Hartmut

“…3′-Hydroxyacetanilide or N-acetyl-meta-aminophenol (AMAP) is generally regarded as a non-hepatotoxic analog of acetaminophen (APAP). Previous studies…”
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Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury by Wang, Shaogui, Ni, Hong-Min, Dorko, Kenneth, Kumer, Sean C, Schmitt, Timothy M, Nawabi, Atta, Komatsu, Masaaki, Huang, Heqing, Ding, Wen-Xing

“…Chronic alcohol exposure increased hepatic receptor-interacting protein kinase (RIP) 3 expression and necroptosis in the liver but its mechanisms are unclear…”
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Subclinical Cognitive Impairment and Listing for Kidney Transplantation by Gupta, Aditi, Montgomery, Robert N, Bedros, Victor, Lesko, John, Mahnken, Jonathan D, Chakraborty, Shweta, Drew, David, Klein, Jeffrey A, Thomas, Tashra S, Ilahe, Amna, Budhiraja, Pooja, Brooks, William M, Schmitt, Timothy M, Sarnak, Mark J, Burns, Jeffrey M, Cibrik, Diane M

“…Cognitive impairment is common in patients with kidney disease and can affect physicians' perception and/or patients' ability to complete the pretransplant…”
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Impact of stem cell marker expression on recurrence of TACE-treated hepatocellular carcinoma post liver transplantation by Zeng, Zhen, Ren, Jinyu, O'Neil, Maura, Zhao, Jie, Bridges, Brian, Cox, Josiah, Abdulkarim, Bashar, Schmitt, Timothy M, Kumer, Sean C, Weinman, Steven A

“…Liver transplantation is the most effective therapy for cirrhosis-associated hepatocellular carcinoma (HCC) but its utility is limited by post-transplant tumor…”
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Pretransplant predictors of recovery of renal function after liver transplantation by Northup, Patrick G., Argo, Curtis K., Bakhru, Mihir R., Schmitt, Timothy M., Berg, Carl L., Rosner, Mitchell H.

“…The Model for End‐Stage Liver Disease system has given priority on the liver transplant waiting list to candidates with renal failure. This study determined…”
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Microcystin-LR induced liver injury in mice and in primary human hepatocytes is caused by oncotic necrosis by Woolbright, Benjamin L., Williams, C. David, Ni, Hongmin, Kumer, Sean C., Schmitt, Timothy, Kane, Bartholomew, Jaeschke, Hartmut

“…Microcystins are a group of toxins produced by freshwater cyanobacteria. Uptake of microcystin-leucine arginine (MC-LR) by organic anion transporting…”
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Pre-transplant portal vein thrombosis is an independent risk factor for graft loss due to hepatic artery thrombosis in liver transplant recipients by Stine, Jonathan G, Pelletier, Shawn J, Schmitt, Timothy M, Porte, Robert J, Northup, Patrick G

“…Abstract Background Hepatic artery thrombosis is an uncommon but catastrophic complication following liver transplantation. We hypothesize that recipients with…”
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Innovation for Reducing Blood Culture Contamination: Initial Specimen Diversion Technique by PATTON, Richard G, SCHMITT, Timothy

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction by Jin, Jing, Nguyen, Le Tra Giang, Wassef, Andrew, Sadek, Ragui, Schmitt, Timothy M, Guo, Grace L, Rasmussen, Theodore P, Zhong, Xiao-Bo

“…The long non-coding RNA (lncRNA) hepatocyte nuclear factor-1 alpha (HNF1A) antisense RNA 1 (HNF1A-AS1) is an important lncRNA for liver growth, development,…”
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Combined Transmesenteric and Transhepatic Recanalization of Chronic Portal and Mesenteric Vein Occlusion to Treat Bleeding Duodenal Varices by Sabri, Saher S., MD, Caldwell, Stephen H., MD, Kumer, Sean C., MD, PhD, Schmitt, Timothy M., MD, Maluf, Daniel G., MD, Angle, John F., MD, Saad, Wael E., MD

“…Abstract Two patients presented with bleeding duodenal varices secondary to mesenteric and portal vein chronic occlusion. After a failed transhepatic…”
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Donor PNPLA3 rs738409 genotype affects fibrosis progression in liver transplantation for hepatitis C by Dunn, Winston, O'Neil, Maura, Zhao, Jie, Wu, Chuang Hong, Roberts, Benjamin, Chakraborty, Shweta, Sherman, Craig, Weaver, Brandy, Taylor, Ryan, Olson, Jody, Olyaee, Mojtaba, Gilroy, Richard, Schmitt, Timothy, Wan, Yu‐Jui Yvonne, Weinman, Steven A.

“…The rs738409 G>C single nucleotide polymorphism occurring in the patatin‐like phospholipase 3 gene has been identified as a novel genetic marker for hepatic…”
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Liver allografts from hepatitis C positive donors can offer good outcomes in hepatitis C positive recipients: a US National Transplant Registry analysis by Northup, Patrick G, Argo, Curtis K, Nguyen, Dennis T, McBride, Maureen A, Kumer, Sean C, Schmitt, Timothy M, Pruett, Timothy L

“…Organ donors are screened for the hepatitis C antibody (anti-HCV) and those with positive tests can be used under extended criteria donation. However, there is…”
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Anti-thymocyte Globulin for the Treatment of Acute Cellular Rejection Following Liver Transplantation by Schmitt, Timothy M, Phillips, Melissa, Sawyer, Robert G, Northup, Patrick, Hagspiel, Klaus D, Pruett, Timothy L, Bonatti, Hugo J. R

“…Introduction Acute cellular rejection (ACR) post-liver transplantation (LT) can usually be reversed with pulse dose steroids. Anti-thymocyte globulin (ATG) is…”
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Combined liver-kidney and liver transplantation in patients with renal failure outcomes in the MELD era by Schmitt, Timothy M, Kumer, Sean C, Al-Osaimi, Abdullah, Shah, Neeral, Argo, Curtis K, Berg, Carl, Pruett, Timothy L, Northup, Patrick G

“…With the implementation of the Model for End-Stage Liver Disease (MELD) scoring system, the number of combined liver-kidney transplants (CLKT) has increased…”
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Hepatolithiasis after Hepaticojejunostomy: Ascaris lumbricoides in the biliary tract by Heimes, Jessica K, Waller, Stephen, Olyee, Mojtaba, Schmitt, Timothy M

“…Biliary ascariasis is a common problem in Third World countries and other underdeveloped areas of the world. Ascaris lumbricoides migrates into the biliary…”
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Sorafenib therapy for hepatocellular carcinoma prior to liver transplant is associated with increased complications after transplant by Truesdale, Aimee E, Caldwell, Stephen H, Shah, Neeral L, Argo, Curtis K, Al-Osaimi, Abdullah M S, Schmitt, Timothy M, Northup, Patrick G

“…This study compared post-transplant outcomes of patients with hepatocellular carcinoma (HCC) who took sorafenib prior to orthotopic liver transplantation (OLT)…”
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