Search Results - "Schmitt, Paul D."

Imaging the Nonlinear Susceptibility Tensor of Collagen by Nonlinear Optical Stokes Ellipsometry by Dow, Ximeng Y., DeWalt, Emma L., Sullivan, Shane Z., Schmitt, Paul D., Ulcickas, James R.W., Simpson, Garth J.

“…Nonlinear optical Stokes ellipsometric (NOSE) microscopy was demonstrated for the analysis of collagen-rich biological tissues. NOSE is based on…”
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Polarization-Modulated Second Harmonic Generation Ellipsometric Microscopy at Video Rate by DeWalt, Emma L, Sullivan, Shane Z, Schmitt, Paul D, Muir, Ryan D, Simpson, Garth J

“…Fast 8 MHz polarization modulation coupled with analytical modeling, fast beam-scanning, and synchronous digitization (SD) have enabled simultaneous nonlinear…”
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Recent Advances in Nonlinear Optical Analyses of Pharmaceutical Materials in the Solid State by Schmitt, Paul D

“…The past decade has seen an increase in the use of nonlinear optical (NLO) techniques such as second harmonic generation, coherent antistokes Raman scattering,…”
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Parts per Million Powder X‑ray Diffraction by Newman, Justin A, Schmitt, Paul D, Toth, Scott J, Deng, Fengyuan, Zhang, Shijie, Simpson, Garth J

“…Here we demonstrate the use of second harmonic generation (SHG) microscopy-guided synchrotron powder X-ray diffraction (PXRD) for the detection of trace…”
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Rapid Discrimination of Polymorphic Crystal Forms by Nonlinear Optical Stokes Ellipsometric Microscopy by Schmitt, Paul D, DeWalt, Emma L, Dow, Ximeng Y, Simpson, Garth J

“…The use of nonlinear optical Stokes ellipsometric (NOSE) microscopy for rapid discrimination of two polymorphic forms of the small molecule d-mannitol is…”
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Second harmonic generation microscopy as a tool for the early detection of crystallization in spray dried dispersions by Correa-Soto, Clara, Trasi, Niraj S., Schmitt, Paul D., Su, Yongchao, Liu, Zhen, Miller, Elise, Variankaval, Narayan, Marsac, Patrick J., Simpson, Garth J., Taylor, Lynne S.

“…•Second harmonic generation (SHG) microscopy was applied for sensitive detection of crystallinity in spray dried particles.•SHG detected crystallinity at an…”
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A Low-Cost Beam-Scanning Second Harmonic Generation Microscope with Application for Agrochemical Development and Testing by Grubbs, Benjamin A, Etter, Nicholas P, Slaughter, Wesley E, Pittsford, Alexander M, Smith, Connor R, Schmitt, Paul D

“…A low-cost second harmonic generation (SHG) microscope was constructed, and, for the first time, SHG microscopy was used for imaging agrochemical materials…”
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Finding the Needle in the Haystack: Characterization of Trace Crystallinity in a Commercial Formulation of Paclitaxel Protein-Bound Particles by Raman Spectroscopy Enabled by Second Harmonic Generation Microscopy by Schmitt, Paul D, Trasi, Niraj S, Taylor, Lynne S, Simpson, Garth J

“…Second harmonic generation (SHG) microscopy was used to rapidly identify regions of interest for localized confocal Raman spectroscopy measurements in order to…”
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Calibration-Free Second Harmonic Generation (SHG) Image Analysis for Quantification of Trace Crystallinity Within Final Dosage Forms of Amorphous Solid Dispersions by Smith, Casey J., Dinh, Janny, Schmitt, Paul D., Stroud, Paul A., Hinds, Jeremy, Johnson, Michael J., Simpson, Garth J.

“…A statistical model enables auto-calibration of second harmonic generation (SHG) images for quantifying trace crystallinity within amorphous solid dispersions…”
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Ab Initio Prediction of the Diversity of Second Harmonic Generation from Pharmaceutically Relevant Materials by Toth, Scott J, Schmitt, Paul D, Snyder, Greg R, Trasi, Niraj S, Sullivan, Shane Z, George, Irene A, Taylor, Lynne S, Simpson, Garth J

“…A model for predicting the anticipated second harmonic generation (SHG) activity of crystalline active pharmaceutical ingredients (APIs) was developed based on…”
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Digital Deconvolution Filter Derived from Linear Discriminant Analysis and Application for Multiphoton Fluorescence Microscopy by Sullivan, Shane Z, Schmitt, Paul D, Muir, Ryan D, DeWalt, Emma L, Simpson, Garth J

“…A digital filter derived from linear discriminant analysis (LDA) is developed for recovering impulse responses in photon counting from a high speed…”
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Coupling qualitative and quantitative analyses of pharmaceutical materials enabled by second harmonic generation microscopy by Schmitt, Paul D

“…The detection and characterization of crystallinity is critical throughout the drug development process. From the initial establishment of an active…”
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SONICC implementation at GM/CA-beamline 23IDB at the Advanced Photon Source by Becker, Michael, Stepanov, Sergey, Newman, Justin A., Sullivan, Shane, Everly, Robert M., Dettmar, Christopher M., Toth, Scott J., Schmitt, Paul D., Corcoran, Stephen, Ferguson, Dale, Fischetti, Robert F., Simpson, Garth J.

“…Abstract only…”
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Surgical Perspectives in Craniofacial Trauma by Schmitt, Paul J., MD, Barrett, Dane M., MD, Christophel, J. Jared, MD, Leiva-Salinas, Carlos, MD, Mukherjee, Sugoto, MD, Shaffrey, Mark E., MD

“…Knowledge of relevant anatomy and underlying mechanisms of traumatic injury is essential for understanding the radiologic findings in craniofacial trauma and…”
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