Search Results - "Schmitt, Frederic"

Organometallic Cages as Vehicles for Intracellular Release of Photosensitizers by Schmitt, Frédéric, Freudenreich, Julien, Barry, Nicolas P. E, Juillerat-Jeanneret, Lucienne, Süss-Fink, Georg, Therrien, Bruno

“…Water-soluble metalla-cages were used to deliver hydrophobic porphin molecules to cancer cells. After internalization, the photosensitizer was photoactivated,…”
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Drug targeting strategies for photodynamic therapy by Schmitt, Frédéric, Juillerat-Jeanneret, Lucienne

“…In human pathologies, therapeutic treatments are often limited by the lack of selectivity of drugs and their elevated effective concentrations. Targeting these…”
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Improvement of meta-tetra(Hydroxyphenyl)chlorin-Like Photosensitizer Selectivity with Folate-Based Targeted Delivery. Synthesis and in Vivo Delivery Studies by Gravier, Julien, Schneider, Raphaël, Frochot, Céline, Bastogne, Thierry, Schmitt, Frédéric, Didelon, Jacques, Guillemin, François, Barberi-Heyob, Muriel

“…The cell membrane folate receptor (FR) is a molecular target for tumor-selective drug delivery, including delivery of photosensitizers for anticancer…”
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Ruthenium Porphyrin Compounds for Photodynamic Therapy of Cancer by Schmitt, Frédéric, Govindaswamy, Padavattan, Süss-Fink, Georg, Ang, Wee Han, Dyson, Paul J, Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…Five 5,10,15,20-tetra(4-pyridyl)porphyrin (TPP) areneruthenium(II) derivatives and a p-cymeneosmium and two pentamethylcyclopentadienyliridium and -rhodium…”
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Cellular delivery of pyrenyl-arene ruthenium complexes by a water-soluble arene ruthenium metalla-cage by Furrer, Mona Anca, Schmitt, Frédéric, Wiederkehr, Michaël, Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…Three pyrenyl-arene ruthenium complexes (M(1)-M(3)) of the general formula [Ru(η(6)-arene-pyrenyl)Cl(2)(pta)] (pta = 1,3,5-triaza-7-phosphaadamantane) have…”
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Increased plasma DYRK1A with aging may protect against neurodegenerative diseases by Delabar, Jean M., Lagarde, Julien, Fructuoso, Marta, Mohammad, Ammara, Bottlaender, Michel, Doran, Eric, Lott, Ira, Rivals, Isabelle, Schmitt, Frederic A., Head, Elizabeth, Sarazin, Marie, Potier, Marie-Claude

“…Early markers are needed for more effective prevention of Alzheimer’s disease. We previously showed that individuals with Alzheimer’s disease have decreased…”
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Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints by Schmitt, Frédéric, Lagopoulos, Lucienne, Käuper, Peter, Rossi, Nathanaël, Busso, Nathalie, Barge, Jérôme, Wagnières, Georges, Laue, Carsten, Wandrey, Christine, Juillerat-Jeanneret, Lucienne

“…Macrophages play key roles in inflammatory disorders. Therefore, they are targets of treatments aiming at their local destruction in inflammation sites…”
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Addressing the COVID-19 pandemic challenges for operational adaptations of a cluster randomized controlled trial on dengue vector control in Malaysia by Saadatian-Elahi, Mitra, Alexander, Neal, Möhlmann, Tim, Ariffin, Farah Diana, Schmitt, Frederic, Richardson, Jason H, Rabilloud, Muriel, Hamid, Nurulhusna Ab

“…The COVID-19 pandemic placed an unprecedented overload on healthcare system globally. With all medical resources being dedicated to contain the spread of the…”
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Experimental evolution supports the potential of neonicotinoid-pyrethroid combination for managing insecticide resistance in malaria vectors by Zoh, Marius Gonse, Bonneville, Jean-Marc, Tutagata, Jordan, Laporte, Frederic, Fodjo, Behi K., Mouhamadou, Chouaibou S., Sadia, Christabelle Gba, McBeath, Justin, Schmitt, Frederic, Horstmann, Sebastian, Reynaud, Stephane, David, Jean-Philippe

“…The introduction of neonicotinoids for managing insecticide resistance in mosquitoes is of high interest as they interact with a biochemical target not…”
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Combined arene ruthenium porphyrins as chemotherapeutics and photosensitizers for cancer therapy by Schmitt, Frédéric, Govindaswamy, Padavattan, Zava, Olivier, Süss-Fink, Georg, Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…Mononuclear 5-(4-pyridyl)-10,15,20-triphenylporphyrin and 5-(3-pyridyl)-10,15,20-triphenylporphyrin as well as tetranuclear…”
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Efficient photodynamic therapy of cancer using chemotherapeutic porphyrin–ruthenium metalla-cubes by Schmitt, Frédéric, Barry, Nicolas P.E., Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…Two cationic arene ruthenium metalla-cubes have been evaluated as potential dual photosensitizers and chemotherapeutics. In the dark, the complexes presented…”
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Deltamethrin and transfluthrin select for distinct transcriptomic responses in the malaria vector Anopheles gambiae by Zoh, Marius Gonse, Bonneville, Jean-Marc, Laporte, Frederic, Tutagata, Jordan, Sadia, Christabelle G, Fodjo, Behi K, Mouhamadou, Chouaibou S, McBeath, Justin, Schmitt, Frederic, Horstmann, Sebastian, Reynaud, Stéphane, David, Jean-Philippe

“…Background The widespread use of pyrethroid insecticides in Africa has led to the development of strong resistance in Anopheles mosquitoes. Introducing new…”
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Anthracene-Tethered Ruthenium(II) Arene Complexes as Tools To Visualize the Cellular Localization of Putative Organometallic Anticancer Compounds by Nazarov, Alexey A, Risse, Julie, Ang, Wee Han, Schmitt, Frederic, Zava, Olivier, Ruggi, Albert, Groessl, Michael, Scopelitti, Rosario, Juillerat-Jeanneret, Lucienne, Hartinger, Christian G, Dyson, Paul J

“…Anthracene derivatives of ruthenium(II) arene compounds with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (pta) or a sugar phosphite ligand, viz.,…”
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Measuring the effectiveness of integrated vector management with targeted outdoor residual spraying and autodissemination devices on the incidence of dengue in urban Malaysia in the iDEM trial (intervention for Dengue Epidemiology in Malaysia): study protocol for a cluster randomized controlled trial by Saadatian-Elahi, Mitra, Alexander, Neal, Möhlmann, Tim, Langlois-Jacques, Carole, Suer, Remco, Ahmad, Nazni Wasi, Mudin, Rose Nani, Ariffin, Farah Diana, Baur, Frederic, Schmitt, Frederic, Richardson, Jason H, Rabilloud, Muriel, Hamid, Nurulhusna Ab

“…Background In common with many South East Asian countries, Malaysia is endemic for dengue. Dengue control in Malaysia is currently based on reactive vector…”
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Photoactive sawhorse-type diruthenium tetracarbonyl complexes by Johnpeter, Justin P., Schmitt, Frédéric, Denoyelle-Di-Muro, Emmanuel, Wagnières, Georges, Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…Photoactivable sawhorse-type dinuclear tetracarbonyl complexes have been prepared and evaluated in human cancer cell lines. One complex demonstrates an…”
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Thermoresponsive Chlorambucil Derivatives for Tumour Targeting by Clavel, Catherine M., Zava, Olivier, Schmitt, Frédéric, Halamoda Kenzaoui, Blanka, Nazarov, Alexey A., Juillerat-Jeanneret, Lucienne, Dyson, Paul J.

“…Putting the heat on: Drugs that are essentially inactive at 37 °C and are active under mild hyperthermia can be synthesized by modification of chlorambucil…”
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Glycoside Esters of 5-Aminolevulinic Acid for Photodynamic Therapy of Cancer by Vallinayagam, Ramakrishnan, Schmitt, Frédéric, Barge, Jérome, Wagnieres, Georges, Wenger, Virginie, Neier, Reinhard, Juillerat-Jeanneret, Lucienne

“…Aliphatic and ethylene glycol esters of 5-aminolevulinic acid (ALA) are very efficient precursors of the photosensitizer protoporphyrin IX (PpIX) for…”
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Catalytic and anticancer activities of sawhorse-type diruthenium tetracarbonyl complexes derived from fluorinated fatty acids by Johnpeter, Justin P., Plasseraud, Laurent, Schmitt, Frédéric, Juillerat-Jeanneret, Lucienne, Therrien, Bruno

“…The reaction of fluorinated fatty acids, perfluorobutyric acid (C 3 F 7 CO 2 H), and perfluorododecanoic acid (C 11 F 23 CO 2 H), with…”
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Sawhorse-type diruthenium tetracarbonyl complexes containing porphyrin-derived ligands as highly selective photosensitizers for female reproductive cancer cells by Schmitt, Frédéric, Auzias, Mathieu, Štěpnička, Petr, Sei, Yoshihisa, Yamaguchi, Kentaro, Süss-Fink, Georg, Therrien, Bruno, Juillerat-Jeanneret, Lucienne

“…Diruthenium tetracarbonyl complexes of the type [Ru₂(CO)₄(μ₂-η²-O₂CR)₂L₂] containing a Ru-Ru backbone with four equatorial carbonyl ligands, two carboxylato…”
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Fate of Hydrophilic Nanoparticles in Biological Environments by Catherine A. Schütz, Frederic Schmitt, Lucienne Juillerat-Jeanneret, Christine Wandrey

“…The nanoparticles developed are based on chitosan, a biocompatible and biodegradable polysaccharide. The chitosan nanoparticles are formed in an entirely…”
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