Search Results - "Schmit, Kristopher J."

Neurodegeneration and neuroinflammation are linked, but independent of alpha‐synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease by Garcia, Pierre, Jürgens‐Wemheuer, Wiebke, Uriarte Huarte, Oihane, Michelucci, Alessandro, Masuch, Annette, Brioschi, Simone, Weihofen, Andreas, Koncina, Eric, Coowar, Djalil, Heurtaux, Tony, Glaab, Enrico, Balling, Rudi, Sousa, Carole, Kaoma, Tony, Nicot, Nathalie, Pfander, Tatjana, Schulz‐Schaeffer, Walter, Allouche, Ahmad, Fischer, Nicolas, Biber, Knut, Kleine‐Borgmann, Felix, Mittelbronn, Michel, Ostaszewski, Marek, Schmit, Kristopher J., Buttini, Manuel

“…A key pathological process in Parkinson's disease (PD) is the transneuronal spreading of α‐synuclein. Alpha‐synuclein (α‐syn) is a presynaptic protein that, in…”
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Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease by Schmit, Kristopher J., Garcia, Pierre, Sciortino, Alessia, Aho, Velma T.E., Pardo Rodriguez, Beatriz, Thomas, Mélanie H., Gérardy, Jean-Jacques, Bastero Acha, Irati, Halder, Rashi, Cialini, Camille, Heurtaux, Tony, Ostahi, Irina, Busi, Susheel B., Grandmougin, Léa, Lowndes, Tuesday, Singh, Yogesh, Martens, Eric C., Mittelbronn, Michel, Buttini, Manuel, Wilmes, Paul

“…Parkinson’s disease (PD) is a neurological disorder characterized by motor dysfunction, dopaminergic neuron loss, and alpha-synuclein (αSyn) inclusions. Many…”
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A New Synuclein-Transgenic Mouse Model for Early Parkinson’s Reveals Molecular Features of Preclinical Disease by Hendrickx, Diana M., Garcia, Pierre, Ashrafi, Amer, Sciortino, Alessia, Schmit, Kristopher J., Kollmus, Heike, Nicot, Nathalie, Kaoma, Tony, Vallar, Laurent, Buttini, Manuel, Glaab, Enrico

“…Understanding Parkinson’s disease (PD), in particular in its earliest phases, is important for diagnosis and treatment. However, human brain samples are…”
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