Search Results - "Schmiedt, R A"

Age-related loss of activity of auditory-nerve fibers by Schmiedt, R A, Mills, J H, Boettcher, F A

“…1. Characteristic frequencies (CF), spontaneous rates (SR), and thresholds were recorded from single fibers in the auditory nerves of gerbils aged for 36 mo in…”
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Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons by Lang, H, Schulte, B A, Schmiedt, R A

“…Application of ouabain to the intact round-window (RW) membrane of the gerbil cochlea induces apoptosis in most spiral ganglion neurons (SGNs), leaving a few…”
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Effects of chronic furosemide treatment and age on cell division in the adult gerbil inner ear by Lang, H, Schulte, B A, Schmiedt, R A

“…Atrophy of the stria vascularis and spiral ligament and an associated decrease in the endocochlear potential (EP) are significant factors in age-related…”
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Endocochlear potentials and compound action potential recovery: functions in the C57BL/6J mouse by Lang, H, Schulte, B.A, Schmiedt, R.A

“…The C57BL/6J mouse suffers from cochlear degeneration beginning at an early age and has been used as a model of age-related hearing loss (presbyacusis). Here,…”
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Ouabain application to the round window of the gerbil cochlea: a model of auditory neuropathy and apoptosis by Schmiedt, R A, Okamura, H-O, Lang, H, Schulte, B A

“…The physiological and morphological changes resulting from acute and chronic infusion of ouabain onto the intact round-window (RW) membrane were examined in…”
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Effects of aging on potassium homeostasis and the endocochlear potential in the gerbil cochlea by Schmiedt, Richard A.

“…Previous work has shown that the endocochlear potential (EP) decreases with age in the gerbil. Concomitant with the EP decrease is an age-related loss of…”
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Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils by Schulte, B A, Schmiedt, R A

“…Changes in the integrity of cochlear ion transport systems with age were examined in gerbils raised for 5-38 months in a quiet environment. Ion transport…”
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Spontaneous rates, thresholds and tuning of auditory-nerve fibers in the gerbil: comparisons to cat data by Schmiedt, R A

“…Characteristics of 245 auditory nerve fibers in eleven Mongolian gerbils are described in terms of spontaneous rates, thresholds, and tuning curves. The…”
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Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis by Gratton, M.A., Schmiedt, R.A., Schulte, B.A.

“…The density and diameter of strial capillaries were assessed in whole-mount preparations of the cochlear lateral wall from 18 gerbils aged in quiet for at…”
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Age-related changes in cochleas of mongolian gerbils by Tarnowski, B I, Schmiedt, R A, Hellstrom, L I, Lee, F S, Adams, J C

“…The effects of aging on the gerbil cochlea were studied in 16 animals raised in a quiet environment. Animals were tested at ages ranging from 33 to 36 months,…”
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Decline in the endocochlear potential corresponds to decreased Na,K-ATPase activity in the lateral wall of quiet-aged gerbils by Gratton, M.A, Smyth, B.J, Lam, C.F, Boettcher, F.A, Schmiedt, R.A

“…The ion transport-mediating enzyme, Na,K-ATPase, is abundantly present in the cochlear lateral wall. This enzyme is essential for the generation and…”
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Age-related changes in auditory potentials of Mongolian gerbil by Mills, J H, Schmiedt, R A, Kulish, L F

“…The Mongolian gerbil is being evaluated as an animal model of age-related hearing loss (presbyacusis). Part of this evaluation involves estimating auditory…”
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Effects of Furosemide Applied Chronically to the Round Window: A Model of Metabolic Presbyacusis by Schmiedt, Richard A, Lang, Hainan, Okamura, Hiro-oki, Schulte, Bradley A

“…Hearing thresholds in elderly humans without a history of noise exposure commonly show a profile of a flat loss at low frequencies coupled with a loss that…”
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Compound action potential input/output functions in young and quiet-aged gerbils by Hellstrom, L I, Schmiedt, R A

“…Auditory-nerve compound action potentials (CAP) and cochlear microphonic (CM) potentials were measured with round window electrodes in two sets of quiet-reared…”
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Development of cochlear potentials in the neonatal gerbil by McGuirt, Joan P., Schmiedt, Richard A., Schulte, Bradley A.

“…The onset and maturation of hearing was examined in separate groups of sibling and nonsibling neonatal Mongolian gerbils ( Meriones unguiculatus). Auditory…”
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Age-related changes in auditory evoked potentials of gerbils. II. Response latencies by Boettcher, F A, Mills, J H, Norton, B L, Schmiedt, R A

“…Auditory brainstem responses (ABR) were recorded in young (6-10 month) and aged (36 month) Mongolian gerbils. Data from the young animals served as the…”
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Tuning and suppression in auditory nerve fibers of aged gerbils raised in quiet or noise by Schmiedt, R A, Mills, J H, Adams, J C

“…Mongolian gerbils were reared either in quiet or in a continuous noise field (85 dBA, 500-4000 Hz). The gerbils began the noise exposure at 8 months of age…”
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Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis by Gratton, M.A., Schmiedt, R.A., Schulte, B.A.

“…The density and diameter of strial capillaries were assessed in whole-mount preparations of the cochlear lateral wall from 18 gerbils aged in quiet for at…”
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Fine structure of the 2f1-f2 acoustic distortion product : changes with primary level by NING-JI HE, SCHMIEDT, R. A

“…The fine frequency structure of the 2f1-f2 acoustic distortion product (ADP fine structure) was examined in ten human subjects with normal hearing. Primary…”
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Acoustic injury and the physiology of hearing by SCHMIEDT, R. A

“…A critical bibliography of published articles concerning the effects of noise exposure on hearing has been compiled for the NIH. The review concentrated on…”
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