Search Results - "Schmidt‐Ott, Urs"
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The Generation of Variation and the Developmental Basis for Evolutionary Novelty
Published in Journal of experimental zoology. Part B, Molecular and developmental evolution (01-09-2012)“…ABSTRACTOrganisms exhibit an incredible diversity of form, a fact that makes the evolution of novelty seemingly self‐evident. However, despite the “obvious”…”
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bicoid occurrence and Bicoid-dependent hunchback regulation in lower cyclorrhaphan flies
Published in Evolution & development (01-07-2008)“…SUMMARY The homeobox gene bicoid functions as an anterior pattern organizer of the Drosophila embryo, but other than in higher flies (Cyclorrhapha), bicoid…”
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Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid
Published in PloS one (03-01-2023)“…The C2H2 zinc finger gene cucoid establishes anterior-posterior (AP) polarity in the early embryo of culicine mosquitoes. This gene is unrelated to genes that…”
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Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms
Published in eLife (08-10-2019)“…Unrelated genes establish head-to-tail polarity in embryos of different fly species, raising the question of how they evolve this function. We show that in…”
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Evidence for a composite anterior determinant in the hover fly Episyrphus balteatus (Syrphidae), a cyclorrhaphan fly with an anterodorsal serosa anlage
Published in Development (Cambridge) (01-01-2009)“…Most insect embryos develop from a monolayer of cells around the yolk, but only part of this blastoderm forms the embryonic rudiment. Another part forms…”
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Chironomus riparius (Diptera) genome sequencing reveals the impact of minisatellite transposable elements on population divergence
Published in Molecular ecology (01-06-2017)“…Active transposable elements (TEs) may result in divergent genomic insertion and abundance patterns among conspecific populations. Upon secondary contact, such…”
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Quantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abdita
Published in eLife (05-01-2015)“…The segmentation gene network in insects can produce equivalent phenotypic outputs despite differences in upstream regulatory inputs between species. We…”
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Functional evolution of a morphogenetic gradient
Published in eLife (22-12-2016)“…Bone Morphogenetic Proteins (BMPs) pattern the dorsal-ventral axis of bilaterian embryos; however, their roles in the evolution of body plan are largely…”
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Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development
Published in eLife (09-10-2018)“…The ancient mechanisms that caused developmental gene regulatory networks to diversify among distantly related taxa are not well understood. Here we use…”
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Evo-Devo aspects of classical and molecular data in a historical perspective
Published in Journal of experimental zoology. Part B, Molecular and developmental evolution (15-01-2004)“…We discuss the interplay between evolution and development as reflected in data and concepts since about 1800. Darwin and his “continental apostle” Haeckel put…”
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BMP-dependent serosa and amnion specification in the scuttle fly Megaselia abdita
Published in Development (Cambridge) (15-09-2012)“…Bone morphogenetic protein (BMP) signaling is an essential factor in dorsoventral patterning of animal embryos but how BMP signaling evolved with fundamental…”
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Evolutionary origin of the amnioserosa in cyclorrhaphan flies correlates with spatial and temporal expression changes of zen
Published in Proceedings of the National Academy of Sciences - PNAS (08-01-2008)“…Higher cyclorrhaphan flies including Drosophila develop a single extraembryonic epithelium (amnioserosa), which closes the germband dorsally. In most other…”
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A Single Hox3 Gene with Composite bicoid and zerknüllt Expression Characteristics in Non-Cyclorrhaphan Flies
Published in Proceedings of the National Academy of Sciences - PNAS (08-01-2002)“…The members of the evolutionarily conserved Hox-gene complex, termed Hox genes, are required for specifying segmental identity during embryogenesis in various…”
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The Anterior Determinant Bicoid of Drosophila Is a Derived Hox Class 3 Gene
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-1999)“…The Drosophila gene bicoid functions as the anterior body pattern organizer of Drosophila. Embryos lacking maternally expressed bicoid fail to develop anterior…”
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BMP signaling components in embryonic transcriptomes of the hover fly Episyrphus balteatus (Syrphidae)
Published in BMC genomics (31-05-2011)“…In animals, signaling of Bone Morphogenetic Proteins (BMPs) is essential for dorsoventral (DV) patterning of the embryo, but how BMP signaling evolved with…”
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Function of Bicoid and Hunchback Homologs in the Basal Cyclorrhaphan Fly Megaselia (Phoridae)
Published in Proceedings of the National Academy of Sciences - PNAS (26-09-2000)“…The Drosophila gene bicoid functions at the beginning of a gene cascade that specifies anterior structures in the embryo. Its transcripts are localized at the…”
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Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution
Published in Development (Cambridge) (01-09-2004)“…Establishment of segmental pattern in the Drosophila syncytial blastoderm embryo depends on pair-rule transcriptional regulators. mRNA transcripts of pair-rule…”
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How two extraembryonic epithelia became one: serosa and amnion features and functions of Drosophila 's amnioserosa
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-12-2022)“…The conservation of gene networks that specify and differentiate distinct tissues has long been a subject of great interest to evolutionary developmental…”
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