Search Results - "Schmidt, Thomas H."

LAMBADA and InflateGRO2: Efficient Membrane Alignment and Insertion of Membrane Proteins for Molecular Dynamics Simulations by Schmidt, Thomas H, Kandt, Christian

“…At the beginning of each molecular dynamics membrane simulation stands the generation of a suitable starting structure which includes the working steps of…”
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Oligomerization of the Tetraspanin CD81 via the Flexibility of Its δ-Loop by Schmidt, Thomas H., Homsi, Yahya, Lang, Thorsten

“…Tetraspanins are master organizers in the plasma membrane, forming tetraspanin-enriched microdomains with one another and other surface molecules. Their…”
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Seroprevalence and correlates of SARS-CoV-2 neutralizing antibodies from a population-based study in Bonn, Germany by Aziz, N. Ahmad, Corman, Victor M., Echterhoff, Antje K. C., Müller, Marcel A., Richter, Anja, Schmandke, Antonio, Schmidt, Marie Luisa, Schmidt, Thomas H., de Vries, Folgerdiena M., Drosten, Christian, Breteler, Monique M. B.

“…To estimate the seroprevalence and temporal course of SARS-CoV-2 neutralizing antibodies, we embedded a multi-tiered seroprevalence survey within an ongoing…”
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The Extracellular δ-Domain is Essential for the Formation of CD81 Tetraspanin Webs by Homsi, Yahya, Schloetel, Jan-Gero, Scheffer, Konstanze D., Schmidt, Thomas H., Destainville, Nicolas, Florin, Luise, Lang, Thorsten

“…CD81 is a ubiquitously expressed member of the tetraspanin family. It forms large molecular platforms, so-called tetraspanin webs that play physiological roles…”
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Packing Density of the Amyloid Precursor Protein in the Cell Membrane by de Coninck, Dennis, Schmidt, Thomas H., Schloetel, Jan-Gero, Lang, Thorsten

“…Plasma membrane proteins organize into structures named compartments, microdomains, rafts, phases, crowds, or clusters. These structures are often smaller than…”
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Concentration Dependent Ion-Protein Interaction Patterns Underlying Protein Oligomerization Behaviours by Batoulis, Helena, Schmidt, Thomas H., Weber, Pascal, Schloetel, Jan-Gero, Kandt, Christian, Lang, Thorsten

“…Salts and proteins comprise two of the basic molecular components of biological materials. Kosmotropic/chaotropic co-solvation and matching ion water…”
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Where Biology Meets Physics--A Converging View on Membrane Microdomain Dynamics by Destainville, Nicolas, Schmidt, Thomas H, Lang, Thorsten

“…For several decades, the phenomenon of membrane component segregation into microdomains has been a well-known and highly debated subject, and varying concepts…”
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Computer simulations suggest direct and stable tip to tip interaction between the outer membrane channel TolC and the isolated docking domain of the multidrug RND efflux transporter AcrB by Schmidt, Thomas H., Raunest, Martin, Fischer, Nadine, Reith, Dirk, Kandt, Christian

“…One way by which bacteria achieve antibiotics resistance is preventing drug access to its target molecule for example through an overproduction of multi-drug…”
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Structural dynamics of the cell wall precursor lipid II in the presence and absence of the lantibiotic nisin by Koch, Dennis C., Schmidt, Thomas H., Sahl, Hans-Georg, Kubitscheck, Ulrich, Kandt, Christian

“…Representing a physiological “Achilles' heel”, the cell wall precursor lipid II (LII) is a prime target for various classes of antibiotics. Over the years…”
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Efflux pump-mediated antibiotics resistance: Insights from computational structural biology by Fischer, Nadine, Raunest, Martin, Schmidt, Thomas H., Koch, Dennis C., Kandt, Christian

“…The continuous rise of bacterial resistance against formerly effective pharmaceuticals is a major challenge for biomedical research. Since the first…”
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LAMBADA & InflateGRO2: Efficient Membrane Alignment and Insertion of Membrane Proteins for Molecular Dynamics Simulations by Schmidt, Thomas H., Kandt, Christian

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Glycosylations Directed by the Armed-Disarmed Effect with Acceptors Containing a Single Ester Group by Schmidt, Thomas H., Madsen, Robert

“…A selective glycosylation reaction controlled by the armed‐disarmed effect is described by the use of phenyl thioglycosides. The donor thioglycoside is fully…”
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LAMBADA and InflateGRO2: Efficient Membrane Alignment and Insertion of Membrane Proteins for Molecular Dvnamics Simulations by SCHMIDT, Thomas H, KANDT, Christian

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The AcrAB-TolC Multidrug Efflux Pump: An Alternative Complex Model by Schmidt, Thomas H., Fischer, Nadine, Kandt, Christian

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Computer Simulations of the Multi-Drug Efflux Pump AcrAB-TolC by Fischer, Nadine, Raunest, Martin, Schmidt, Thomas H., Kandt, Christian

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The Extracellular [Delta]-Domain is Essential for the Formation of CD81 Tetraspanin Webs by Homsi, Yahya, Schloetel, Jan-Gero, Scheffer, Konstanze D, Schmidt, Thomas H, Destainville, Nicolas, Florin, Luise, Lang, Thorsten

“…CD81 is a ubiquitously expressed member of the tetraspanin family. It forms large molecular platforms, so-called tetraspanin webs that play physiological roles…”
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Atomistic and Coarse-Grain Computer Simulations of the Assembled AcrAB-TolC Multidrug Efflux Pump by Schmidt, Thomas H., Fischer, Nadine, Raunest, Martin, Kandt, Christian

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A 2600-year history of floods in the Bernese Alps, Switzerland: frequencies, mechanisms and climate forcing by Schulte, L, Peña, J. C, Carvalho, F, Schmidt, T, Julià, R, Llorca, J, Veit, H

“…A 2600-year long composite palaeoflood record is reconstructed from high-resolution delta plain sediments of the Hasli–Aare floodplain on the northern slope of…”
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Aspects of Explosives Detection by Marshall, Maurice, Oxley, Jimmie C

“…Detection and quantification of trace chemicals is a major thrust of analytical chemistry. In recent years much effort has been spent developing detection…”
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Regulatory system needs overhaul by SCHMIDT, THOMAS H

“…A commentary contends that environmental regulatory reform is absolutely essential if the US paper industry is to remain economically competitive in a global…”
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