Search Results - "Schmidt, S D"
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A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease
Published in Neurobiology of disease (01-10-2001)“…Clinical, epidemiological, and laboratory studies suggest that cholesterol may play a role in the pathogenesis of Alzheimer's disease (AD). Transgenic mice…”
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2
Electrostatic force on saltating sand
Published in Journal of Geophysical Research (27-04-1998)“…In blizzards and sandstorms, wind transport of particles is associated with separation of electrostatic charge. Moving particles develop charge of sign…”
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3
Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy
Published in British journal of anaesthesia : BJA (01-07-2016)“…Single-dose human fibrinogen concentrate (FCH) might have haemostatic benefits in complex cardiovascular surgery. Patients undergoing elective aortic surgery…”
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4
Components of N-fixation system response to glyphosate are un-coupled in agroecosystems
Published in Applied soil ecology : a section of Agriculture, ecosystems & environment (01-08-2023)“…Glyphosate, introduced 50 years ago, is one of the most widely used herbicides. There are lingering concerns over the potential environmental impacts of…”
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5
Mass value assignment of total and subclass immunoglobulin G in a human standard anthrax reference serum
Published in Clinical and diagnostic laboratory immunology (01-09-2004)“…An anti-Anthrax Vaccine Adsorbed (anti-AVA) standard human reference serum pool, AVR414, has been prepared, and the total and protective antigen (PA)-specific…”
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6
Modulation of the consolidation and reconsolidation of fear memory by three different serotonin receptors in hippocampus
Published in Neurobiology of learning and memory (01-07-2017)“…•5-HT5, 5-HT6 and 5-HT7 participate of the stabilization processes of fear memory.•The 5-HT5R participate of the reconsolidation of fear memory in the CA1…”
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Analysis of anti-protective antigen IgG subclass distribution in recipients of anthrax vaccine adsorbed (AVA) and patients with cutaneous and inhalation anthrax
Published in Vaccine (26-02-2007)“…Abstract The anti-PA IgG1, IgG2, IgG3, and IgG4 subclass responses to clinical anthrax and to different numbers of anthrax vaccine adsorbed (AVA, BioThrax® )…”
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8
PACAP modulates the consolidation and extinction of the contextual fear conditioning through NMDA receptors
Published in Neurobiology of learning and memory (01-02-2015)“…•PACAP modulates the consolidation of the CFC in the CA1 and in the BLA.•The extinction of the contextual fear conditioning is modulated by PACAP in the…”
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9
Electrostatic force in blowing snow
Published in Boundary-layer meteorology (01-10-1999)“…Separation of electrostatic charge during the transport of particles by wind adds a force to the gravitational and fluid forces that determine trajectories of…”
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10
A novel presenilin-1 mutation: increased beta-amyloid and neurofibrillary changes
Published in Annals of neurology (01-06-1997)“…The prevalence of known mutations in presenilin genes (PS1 and PS2) causing early-onset familial Alzheimer's disease (FAD) was assessed in a population of 98…”
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11
Validation and long term performance characteristics of a quantitative enzyme linked immunosorbent assay (ELISA) for human anti-PA IgG
Published in Journal of immunological methods (28-02-2012)“…Accurate, reliable and standardized quantification of anti-protective antigen (PA) IgG antibody levels is essential for comparative analyses of anti-toxin…”
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12
Normal brain development in PS1 hypomorphic mice with markedly reduced γ-secretase cleavage of βAPP
Published in Neurobiology of aging (01-03-2002)Get full text
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13
Staurosporine‐Induced Activation of Caspase‐3 Is Potentiated by Presenilin 1 Familial Alzheimer's Disease Mutations in Human Neuroglioma Cells
Published in Journal of neurochemistry (01-12-1999)“…: Familial Alzheimer's disease (FAD) mutant forms of presenilin 1 (PS1) and 2 have been shown to sensitize cells to apoptotic cell death. Here we explore the…”
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14
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
Published in Nature (London) (21-12-2000)“…Much evidence indicates that abnormal processing and extracellular deposition of amyloid-β peptide (Aβ), a proteolytic derivative of the β-amyloid precursor…”
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15
CD44 variant isoforms on blood leukocytes in chronic inflammatory bowel disease and other systemic autoimmune diseases
Published in Laboratory investigation (01-06-1999)“…We have described recently that TNBS-induced colitis, an animal model of chronic inflammatory bowel disease (IBD), can be cured by treatment with anti-CD44v7…”
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16
Preliminary experimental evidence of heating at the running surface of avalanching snow
Published in Cold regions science and technology (01-11-2003)“…At the Montana State University Avalanche Research Site, instrumentation has been installed to measure temperatures, flow depth, and velocities during an…”
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Anti-glycoprotein B monoclonal antibody protects T cell-depleted mice against herpes simplex virus infection by inhibition of virus replication at the inoculated mucous membranes
Published in Journal of general virology (01-03-1993)“…Institute of Medical Microbiology and Immunology, University of Bonn, Sigmund-Freud-Strasse 25, D-5300 Bonn 1, Germany A monoclonal antibody (MAb 2c) specific…”
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18
Rab5-stimulated Up-regulation of the Endocytic Pathway Increases Intracellular β-Cleaved Amyloid Precursor Protein Carboxyl-terminal Fragment Levels and Aβ Production
Published in The Journal of biological chemistry (15-08-2003)“…We previously identified abnormalities of the endocytic pathway in neurons as the earliest known pathology in sporadic Alzheimer's disease (AD) and Down's…”
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The CD44 variant isoforms CD44v6 and CD44v7 are expressed by distinct leukocyte subpopulations and exert non-overlapping functional activities
Published in International immunology (01-01-2000)“…We have described recently that anti-CD44s, anti-CD44v6 and anti-CD44v7 interfere with delayed-type hypersensitivity (DTH) reactions. Yet, TNBS-induced colitis…”
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In vivo Reduction of Amyloid-β by a Mutant Copper Transporter
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2003)“…Cu ions have been suggested to enhance the assembly and pathogenic potential of the Alzheimer's disease$amyloid\!-\!\beta\>(A\beta)$peptide. To explore this…”
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