Search Results - "Schmidt, Jeanette P"
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Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array data
Published in PloS one (17-11-2022)“…The UK Biobank genotyped about 500k participants using Applied Biosystems Axiom microarrays. Participants were subsequently sequenced by the UK Biobank Exome…”
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Predicting Allosteric Communication in Myosin via a Pathway of Conserved Residues
Published in Journal of molecular biology (09-11-2007)“…We present a computational method that predicts a pathway of residues that mediate protein allosteric communication. The pathway is predicted using only a…”
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Journal Article -
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The Simbios National Center: Systems Biology in Motion
Published in Proceedings of the IEEE (01-08-2008)“…Physics-based simulation is needed to understand the function of biological structures and can be applied across a wide range of scales, from molecules to…”
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Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
Published in Nature communications (13-06-2014)“…A major use of the 1000 Genomes Project (1000GP) data is genotype imputation in genome-wide association studies (GWAS). Here we develop a method to estimate…”
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Journal Article -
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Historical queries along multiple lines of time evolution
Published in The VLDB journal (01-10-1995)“…Traditional approaches to addressing historical queries assume a single line of time evolution; that is, a system (database, relation) evolves over time…”
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An algorithm for approximate tandem repeats
Published in Journal of computational biology (01-01-2001)“…A perfect single tandem repeat is defined as a nonempty string that can be divided into two identical substrings, e.g., abcabc. An approximate single tandem…”
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The Simbios National Center : Systems Biology in Motion: Computational Systems Biology
Published in Proceedings of the IEEE (2008)Get full text
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All shortest paths in weighted grid graphs and its application to finding all approximate repeats in strings
Published in Proceedings Third Israel Symposium on the Theory of Computing and Systems (1995)“…Shortest paths in directed grid graphs of dimension (m/spl times/n) can be used to model the string edit problem, which consists of obtaining optimal…”
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Conference Proceeding -
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Efficient support of historical queries for multiple lines of evolution
Published in Proceedings of IEEE 9th International Conference on Data Engineering (1993)“…A general framework for solving multiple-line history queries is presented. The authors address two important historical queries in this environment: the…”
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Conference Proceeding