Search Results - "Schmidt, Hartmut H J"

"Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy by Conceição, Isabel, González-Duarte, Alejandra, Obici, Laura, Schmidt, Hartmut H.-J., Simoneau, Damien, Ong, Moh-Lim, Amass, Leslie

“…© 2015 The Authors. Journal of the Peripheral Nervous System published by Wiley Periodicals, Inc. on behalf of Peripheral Nerve Society. This is an open access…”
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Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute‐on‐chronic liver failure: The RELIEF trial by Bañares, Rafael, Nevens, Frederik, Larsen, Fin Stolze, Jalan, Rajiv, Albillos, Agustín, Dollinger, Matthias, Saliba, Faouzi, Sauerbruch, Tilman, Klammt, Sebastian, Ockenga, Johann, Pares, Albert, Wendon, Julia, Brünnler, Tanja, Kramer, Ludwig, Mathurin, Philippe, de la Mata, Manuel, Gasbarrini, Antonio, Müllhaupt, Beat, Wilmer, Alexander, Laleman, Wim, Eefsen, Martin, Sen, Sambit, Zipprich, Alexander, Tenorio, Teresa, Pavesi, Marco, Schmidt, Hartmut H.‐J., Mitzner, Steffen, Williams, Roger, Arroyo, Vicente

“…Acute‐on‐chronic liver failure (ACLF) is a frequent cause of death in cirrhosis. Albumin dialysis with the molecular adsorbent recirculating system (MARS)…”
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Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy by Coelho, Teresa, Maia, Luis F., da Silva, Ana Martins, Cruz, Márcia W., Planté-Bordeneuve, Violaine, Suhr, Ole B., Conceiçao, Isabel, Schmidt, Hartmut H.-J., Trigo, Pedro, Kelly, Jeffery W., Labaudinière, Richard, Chan, Jason, Packman, Jeff, Grogan, Donna R.

“…Tafamidis, a transthyretin (TTR) kinetic stabilizer, delayed neuropathic progression in patients with Val30Met TTR familial amyloid polyneuropathy (TTR-FAP) in…”
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Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review by Gillessen, Anton, Schmidt, Hartmut H.-J.

“…Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic conditions. Preclinical data indicate that silymarin can reduce…”
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Management of asymptomatic gene carriers of transthyretin familial amyloid polyneuropathy by Schmidt, Hartmut H.-J., Barroso, Fabio, González-Duarte, Alejandra, Conceição, Isabel, Obici, Laura, Keohane, Denis, Amass, Leslie

“…© 2016 The Authors Muscle & Nerve Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons…”
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Progressive Hereditary Transthyretin-Related Amyloidosis (ATTRv) Aggravated by ATTR Wild-Type and Complement Activation by Mattig, Isabel, Heidecker, Bettina, Tschöpe, Carsten, Messroghli, Daniel, Eurich, Dennis, Kleefeld, Felix, Gaedeke, Jens, Stenzel, Werner, Schmidt, Hartmut H -J, Röcken, Christoph, Knebel, Fabian, Hahn, Katrin

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Intragenic Deletions in ATP7B as an Unusual Molecular Genetics Mechanism of Wilson's Disease Pathogenesis by Todorov, Theodor, Balakrishnan, Prahlad, Savov, Alexey, Socha, Piotr, Schmidt, Hartmut H J

“…Wilson's disease (WD) is an autosomal recessive disorder caused by mutations in the ATP7B resulting in copper overload in the liver and brain. Direct…”
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Molecular adsorbent recirculating system (MARS) in acute liver injury and graft dysfunction: Results from a case-control study by Gerth, Hans U, Pohlen, Michele, Thölking, Gerold, Pavenstädt, Hermann, Brand, Marcus, Wilms, Christian, Hüsing-Kabar, Anna, Görlich, Dennis, Kabar, Iyad, Schmidt, Hartmut H J

“…The primary therapeutic goals in the treatment of liver injury are to support liver regeneration or bridge the gap to liver transplantation (LT). Molecular…”
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Association of contact to small children with a mild course of COVID-19 by Dugas, Martin, Schrempf, Inga-Marie, Ochs, Kevin, Frömmel, Christopher, Greulich, Leonard, Neuhaus, Philipp, Tepasse, Phil-Robin, Schmidt, Hartmut H.-J.

“…•A survey of a large cohort with predominantly mild course of COVID-19 was conducted.•6.9% reported regular job-related contact with children below ten…”
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Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells by Niemietz, Christoph J, Sauer, Vanessa, Stella, Jacqueline, Fleischhauer, Lutz, Chandhok, Gursimran, Guttmann, Sarah, Avsar, Yesim, Guo, Shuling, Ackermann, Elizabeth J, Gollob, Jared, Monia, Brett P, Zibert, Andree, Schmidt, Hartmut H-J

“…Familial amyloid polyneuropathy (FAP) is caused by mutations of the transthyretin (TTR) gene, predominantly expressed in the liver. Two compounds that…”
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Enhanced monitoring and detection of recent genotype 3 hepatitis E virus infection through urine antigen testing by Stahl, Yannick, Kabar, Iyad, Heinzow, Hauke, Maasoumy, Benjamin, Bremer, Birgit, Wedemeyer, Heiner, Schmidt, Hartmut H.-J., Pietschmann, Thomas, Schlevogt, Bernhard, Behrendt, Patrick

“…Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis. Numerous studies have investigated the dynamics of HEV infection markers, but the most…”
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New Prognostic Score (Essen Score) to Predict Postoperative Morbidity after Resection of Lung Metastases by Grapatsas, Konstantinos, Dörr, Fabian, Menghesha, Hruy, Schuler, Martin, Grünwald, Viktor, Bauer, Sebastian, Schmidt, Hartmut H. -J., Lang, Stephan, Kimmig, Rainer, Kasper, Stefan, Baldes, Natalie, Bölükbas, Servet

“…Background: Pulmonary metastasectomy (PM) is a widely accepted surgical procedure. This study aims to investigate postoperative morbidity and mortality after…”
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Bilobar Radioembolization Carries the Risk of Radioembolization-Induced Liver Disease in the Treatment of Advanced Hepatocellular Carcinoma: Safety and Efficacy Comparison to Systemic Therapy with Atezolizumab/Bevacizumab by Jeschke, Matthias, Ludwig, Johannes M, Leyh, Catherine, Pabst, Kim M, Weber, Manuel, Theysohn, Jens M, Lange, Christian M, Herrmann, Ken, Schmidt, Hartmut H-J, Jochheim, Leonie S

“…Recommended treatment options for advanced-stage hepatocellular carcinoma (HCC) include systemic therapy (ST) and trans-arterial radioembolization (TARE) with…”
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Spatial investigation of the elemental distribution in Wilson’s disease liver after d-penicillamine treatment by LA-ICP-MS by Hachmöller, Oliver, Zibert, Andree, Zischka, Hans, Sperling, Michael, Groba, Sara Reinartz, Grünewald, Inga, Wardelmann, Eva, Schmidt, Hartmut H.-J., Karst, Uwe

“…At present, the copper chelator d-penicillamine (DPA) is the first-line therapy of Wilson’s disease (WD), which is characterized by an excessive copper…”
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The effect of zinc and D-penicillamine in a stable human hepatoma ATP7B knockout cell line by Chandhok, Gursimran, Schmitt, Nadine, Sauer, Vanessa, Aggarwal, Annu, Bhatt, Mohit, Schmidt, Hartmut H J

“…Mutations in the copper (Cu) transporter gene ATP7B, the primary cause of Wilson disease (WD), result in high liver Cu and death of hepatocytes. Cu chelators…”
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Higher pNRF2, SOCS3, IRF3, and RIG1 Tissue Protein Expression in NASH Patients versus NAFL Patients: pNRF2 Expression Is Concomitantly Associated with Elevated Fasting Glucose Levels by Schwertheim, Suzan, Alhardan, Malek, Manka, Paul P, Sowa, Jan-Peter, Canbay, Ali, Schmidt, Hartmut H-J, Baba, Hideo A, Kälsch, Julia

“…Non-alcoholic fatty liver disease (NAFLD) embraces simple steatosis in non-alcoholic fatty liver (NAFL) to advanced non-alcoholic steatohepatitis (NASH)…”
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Organ-Protective Intensive Care in Organ Donors by Hahnenkamp, Klaus, Böhler, Klaus, Wolters, Heiner, Wiebe, Karsten, Schneider, Dietmar, Schmidt, Hartmut H-J

“…The ascertainment of brain death (the irreversible, total loss of brain function) gives the physician the opportunity to limit or stop further treatment…”
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Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson’s disease by Terwel, Dick, Löschmann, Yi‐Na, Schmidt, Hartmut H.‐J., Schöler, Hans R., Cantz, Tobias, Heneka, Michael T.

“…J. Neurochem. (2011) 10.1111/j.1471‐4159.2011.07278.x Wilson’s disease (WD) is caused by mutations in the copper transporting ATPase 7B (Atp7b). Patients…”
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Evaluation of domino liver transplantations in Germany by Bolte, Fabian Johannes, Schmidt, Hartmut H-J, Becker, Thomas, Braun, Felix, Pascher, Andreas, Klempnauer, Jürgen, Schmidt, Jan, Nadalin, Silvio, Otto, Gerd, Barreiros, Ana Paula

“…A retrospective multicenter study has been conducted to evaluate domino liver transplantations (DLTs) in Germany. The study provides insight into survival and…”
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LMNA Mutations, Skeletal Muscle Lipid Metabolism, and Insulin Resistance by Boschmann, Michael, Engeli, Stefan, Moro, Cedric, Luedtke, Angelika, Adams, Frauke, Gorzelniak, Kerstin, Rahn, Gabriele, Mähler, Anja, Dobberstein, Kerstin, Krüger, Antje, Schmidt, Saskia, Spuler, Simone, Luft, Friedrich C, Smith, Steven R, Schmidt, Hartmut H.-J, Jordan, Jens

“…Context: Type 2 familial partial lipodystrophy (FPLD) is an autosomal-dominant lamin A/C-related disease associated with exercise intolerance, muscular pain,…”
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