Search Results - "Schmidt, Florian"
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Wide-field imaging of gas-phase K species in biomass combustion using photofragmentation laser absorption imaging
Published in Fuel (Guildford) (01-02-2025)“…[Display omitted] •A technique for quantitative wide-field imaging of K, KOH and KCl is presented.•Below parts-per-million detection limits are reached at…”
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ICL-based TDLAS sensor for real-time breath gas analysis of carbon monoxide isotopes
Published in Optics express (29-05-2017)“…We present a compact sensor for carbon monoxide (CO) in air and exhaled breath based on a room temperature interband cascade laser (ICL) operating at 4.69 µm,…”
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HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
Published in Science (American Association for the Advancement of Science) (18-09-2020)“…Inflammasomes are supramolecular complexes that play key roles in immune surveillance. This is accomplished by the activation of inflammatory caspases, which…”
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Exploiting Nanobodies' Singular Traits
Published in Annual review of immunology (26-04-2018)“…The unique class of heavy chain-only antibodies, present in Camelidae, can be shrunk to just the variable region of the heavy chain to yield VHHs, also called…”
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Ultrafast Widefield Mid-Infrared Photothermal Heterodyne Imaging
Published in Analytical chemistry (Washington) (18-10-2022)“…Mid-infrared photothermal (MIP) microscopy is a valuable tool for sensitive and fast chemical imaging with high spatial resolution beyond the mid-infrared…”
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Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Published in Science (American Association for the Advancement of Science) (12-02-2021)“…The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread, with devastating consequences. For passive…”
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Real-time breath gas analysis of CO and CO2 using an EC-QCL
Published in Applied physics. B, Lasers and optics (01-05-2017)“…Real-time breath gas analysis is a promising, non-invasive tool in medical diagnostics, and well-suited to investigate the physiology of carbon monoxide (CO),…”
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From atoms to physiology: what it takes to really understand inflammasomes
Published in The Journal of physiology (01-11-2019)“…Rapid inflammatory responses to cytosolic threats are mediated by inflammasomes – large macromolecular signalling complexes that control the activation of the…”
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Real-time in situ multi-parameter TDLAS sensing in the reactor core of an entrained-flow biomass gasifier
Published in Proceedings of the Combustion Institute (2017)“…Tunable diode laser absorption spectroscopy (TDLAS) was used to measure several important process parameters at two different locations inside the reactor of…”
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AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Published in Science (American Association for the Advancement of Science) (10-06-2022)“…INTRODUCTION The eukaryotic nucleus pro-tects the genome and is enclosed by the two membranes of the nuclear envelope. Nuclear pore complexes (NPCs) perforate…”
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Laser spectroscopy for breath analysis: towards clinical implementation
Published in Applied physics. B, Lasers and optics (2018)“…Detection and analysis of volatile compounds in exhaled breath represents an attractive tool for monitoring the metabolic status of a patient and disease…”
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Quantitative Tomographic Laser Absorption Imaging of Atomic Potassium during Combustion of Potassium Chloride Salt and Biomass
Published in Analytical chemistry (Washington) (17-01-2023)“…Gaseous potassium (K) species play an important role in biomass combustion processes, and imaging techniques are powerful tools to investigate the related…”
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13
Solvate Cation Migration and Ion Correlations in Solvate Ionic Liquids
Published in The journal of physical chemistry. B (20-02-2020)“…Lithium salt–glyme mixtures are interesting candidates as electrolytes for battery applications. Depending on the type of glyme or anion and the salt…”
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Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever
Published in PLoS biology (07-11-2022)“…Pyrin is a cytosolic immune sensor that nucleates an inflammasome in response to inhibition of RhoA by bacterial virulence factors, triggering the release of…”
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Laser-based detection of methane and soot during entrained-flow biomass gasification
Published in Combustion and flame (01-03-2022)“…Methane is one of the main gas species produced during biomass gasification and may be a desired or undesired product. Syngas CH4 concentrations are typically…”
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Oxy-fuel combustion of softwood in a pilot-scale down-fired pulverized combustor – Fate of potassium
Published in Fuel (Guildford) (01-02-2025)“…[Display omitted] •First oxy-fuel combustion of biomass in a 100 kW down-fired pulverized combustor.•First in situ measurement of gaseous K, KOH and KCl in…”
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Tunable Diode Laser Absorption Spectroscopy Diagnostics of Potassium, Carbon Monoxide, and Soot in Oxygen-Enriched Biomass Combustion Close to Stoichiometry
Published in Energy & fuels (21-11-2019)“…Combustion facilities run on pulverized biomass often exhibit fluctuations in fuel feeding and, thus, equivalence ratio and would benefit from fast process…”
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Transcriptional recording by CRISPR spacer acquisition from RNA
Published in Nature (London) (01-10-2018)“…The ability to record transcriptional events within a cell over time would help to elucidate how molecular events give rise to complex cellular behaviours and…”
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Jack of all trades inhibits inflammation (in sober people)
Published in Nature immunology (01-07-2020)“…Caspase-cleaved gasdermin D forms pores in cellular membranes, thus executing proinflammatory cell death by pyroptosis. Disulfiram — a drug used to treat…”
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A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly
Published in The Journal of experimental medicine (02-05-2016)“…Myeloid cells assemble inflammasomes in response to infection or cell damage; cytosolic sensors activate pro-caspase-1, indirectly for the most part, via the…”
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