Search Results - "Schmidt, Felix"

Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance by Schmidt, Felix, Efferth, Thomas

“…Tumor heterogeneity has been compared with Darwinian evolution and survival of the fittest. The evolutionary ecosystem of tumors consisting of heterogeneous…”
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A ballistic graphene superconducting microwave circuit by Schmidt, Felix E., Jenkins, Mark D., Watanabe, Kenji, Taniguchi, Takashi, Steele, Gary A.

“…Josephson junctions (JJ) are a fundamental component of microwave quantum circuits, such as tunable cavities, qubits, and parametric amplifiers. Recently…”
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Bacteria exploit a polymorphic instability of the flagellar filament to escape from traps by Kühn, Marco J., Schmidt, Felix K., Eckhardt, Bruno, Thormann, Kai M.

“…Many bacterial species swim by rotating single polar helical flagella. Depending on the direction of rotation, they can swim forward or backward and change…”
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Cross-species analysis of hepatic cytochrome P450 and transport protein expression by Hammer, Helen, Schmidt, Felix, Marx-Stoelting, Philip, Pötz, Oliver, Braeuning, Albert

“…Most drugs and xenobiotics are metabolized in the liver. Amongst others, different cytochrome P450 (CYP) enzymes catalyze the metabolic conversion of foreign…”
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Approaching virtual osteoid volume estimation and in-depth tissue characterization in patients with tumor-induced osteomalacia by Schmidt, Felix N, Delsmann, Julian, Yazigi, Bashar, Beil, Frank Timo, Amling, Michael, Oheim, Ralf

“…Tumor-induced osteomalacia (TIO) poses a significant diagnostic challenge, leading to increased disease duration and patient burden also by missing clinical…”
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Single-Atom Quantum Probes for Ultracold Gases Boosted by Nonequilibrium Spin Dynamics by Bouton, Quentin, Nettersheim, Jens, Adam, Daniel, Schmidt, Felix, Mayer, Daniel, Lausch, Tobias, Tiemann, Eberhard, Widera, Artur

“…Quantum probes are atomic sized devices mapping information of their environment to quantum-mechanical states. By improving measurements and at the same time…”
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Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients – A retrospective study by Wiedemann, Philip, Schmidt, Felix N., Amling, Michael, Yorgan, Timur A., Barvencik, Florian

“…Hypophosphatasia (HPP) is characterized by severe skeletal symptoms including mineralization defects, insufficiency fractures, and delayed facture healing or…”
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Radial HR-pQCT and Finite Element Analysis in HPP Patients are Superior in Identifying Susceptibility to Fracture-Associated Skeletal Affections Compared to DXA and Laboratory Tests by Schmidt, Felix N., Schmidt, Constantin, Delsmann, Julian, Amling, Michael, Barvencik, Florian

“…Hypophosphatasia (HPP) is an inborn disease that causes a rare form of osteomalacia, a mineralization disorder affecting mineralized tissues. Identification of…”
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Rapid sequestration of perovskite solar cell-derived lead in soil by Schmidt, Felix, Ledermann, Luca, Schäffer, Andreas, Snaith, Henry J., Lenz, Markus

“…Efficient and stable perovskite solar cells rely on the use of Pb species potentially challenging the technologies’ commercialisation. In this study, the fate…”
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Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments by Kühn, Marco J., Schmidt, Felix K., Farthing, Nicola E., Rossmann, Florian M., Helm, Bina, Wilson, Laurence G., Eckhardt, Bruno, Thormann, Kai M.

“…Bacterial flagella are helical proteinaceous fibers, composed of the protein flagellin, that confer motility to many bacterial species. The genomes of about…”
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Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study by Bartosik, Mikolaj, Simon, Alexander, Strahl, André, Oheim, Ralf, Amling, Michael, Schmidt, Felix N.

“…In-vivo bone microstructure measured by high-resolution peripheral quantitative computed tomography (HR-pQCT) is gaining importance in research and clinical…”
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Individual Tracer Atoms in an Ultracold Dilute Gas by Hohmann, Michael, Kindermann, Farina, Lausch, Tobias, Mayer, Daniel, Schmidt, Felix, Lutz, Eric, Widera, Artur

“…We report on the experimental investigation of individual Cs atoms impinging on a dilute cloud of ultracold Rb atoms with variable density. We study the…”
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Mechanical Competence and Bone Quality Develop During Skeletal Growth by Zimmermann, Elizabeth A, Riedel, Christoph, Schmidt, Felix N, Stockhausen, Kilian E, Chushkin, Yuriy, Schaible, Eric, Gludovatz, Bernd, Vettorazzi, Eik, Zontone, Federico, Püschel, Klaus, Amling, Michael, Ritchie, Robert O, Busse, Björn

“…ABSTRACT Bone fracture risk is influenced by bone quality, which encompasses bone's composition as well as its multiscale organization and architecture. Aging…”
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Assessment and comparison of the max-ICH score and ICH score by external validation by Schmidt, Felix A, Liotta, Eric M, Prabhakaran, Shyam, Naidech, Andrew M, Maas, Matthew B

“…OBJECTIVEWe tested the hypothesis that the maximally treated intracerebral hemorrhage (max-ICH) score is superior to the ICH score for characterizing mortality…”
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Long‐Term Immobilization in Elderly Females Causes a Specific Pattern of Cortical Bone and Osteocyte Deterioration Different From Postmenopausal Osteoporosis by Rolvien, Tim, Milovanovic, Petar, Schmidt, Felix N, Kroge, Simon, Wölfel, Eva M, Krause, Matthias, Wulff, Birgit, Püschel, Klaus, Ritchie, Robert O, Amling, Michael, Busse, Björn

“…ABSTRACT Immobilization as a result of long‐term bed rest can lead to gradual bone loss. Because of their distribution throughout the bone matrix and…”
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Severely Impaired Bone Material Quality in Chihuahua Zebrafish Resembles Classical Dominant Human Osteogenesis Imperfecta by Fiedler, Imke A.K., Schmidt, Felix N., Wölfel, Eva M., Plumeyer, Christine, Milovanovic, Petar, Gioia, Roberta, Tonelli, Francesca, Bale, Hrishikesh A., Jähn, Katharina, Besio, Roberta, Forlino, Antonella, Busse, Björn

“…ABSTRACT Excessive skeletal deformations and brittle fractures in the vast majority of patients suffering from osteogenesis imperfecta (OI) are a result of…”
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Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia by Stürznickel, Julian, Schmidt, Felix N., von Vopelius, Emil, Delsmann, Maximilian M., Schmidt, Constantin, Jandl, Nico Maximilian, Oheim, Ralf, Barvencik, Florian

“…Hypophosphatasia (HPP) is a hereditary musculoskeletal disorder caused by inactivating variants in the ALPL gene and subsequently reduced serum…”
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Super Resolution Fluorescence Microscopy and Tracking of Bacterial Flotillin (Reggie) Paralogs Provide Evidence for Defined-Sized Protein Microdomains within the Bacterial Membrane but Absence of Clusters Containing Detergent-Resistant Proteins by Dempwolff, Felix, Schmidt, Felix K, Hervás, Ana B, Stroh, Alex, Rösch, Thomas C, Riese, Cornelius N, Dersch, Simon, Heimerl, Thomas, Lucena, Daniella, Hülsbusch, Nikola, Stuermer, Claudia A O, Takeshita, Norio, Fischer, Reinhard, Eckhardt, Bruno, Graumann, Peter L

“…Biological membranes have been proposed to contain microdomains of a specific lipid composition, in which distinct groups of proteins are clustered…”
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Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells by Goedtke, Lisa, Sprenger, Heike, Hofmann, Ute, Schmidt, Felix F, Hammer, Helen S, Zanger, Ulrich M, Poetz, Oliver, Seidel, Albrecht, Braeuning, Albert, Hessel-Pras, Stefanie

“…Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants produced by incomplete combustion of organic matter. They induce their own metabolism by…”
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Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols by Camilleri, Angelique, Zarb, Claire, Caruana, Mario, Ostermeier, Ulrike, Ghio, Stephanie, Högen, Tobias, Schmidt, Felix, Giese, Armin, Vassallo, Neville

“…Alzheimer's disease and Parkinson's disease are neurodegenerative disorders characterised by the misfolding of proteins into soluble prefibrillar aggregates…”
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