Search Results - "Schmid, Ruth"
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Delivering the power of nanomedicine to patients today
Published in Journal of controlled release (10-10-2020)“…The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified…”
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The solid progress of nanomedicine
Published in Drug delivery and translational research (01-06-2020)“…This commentary article conveys the views of the board of the Nanomedicine and Nanoscale Delivery Focus Group of the Controlled Release Society regarding the…”
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A translational framework to DELIVER nanomedicines to the clinic
Published in Nature nanotechnology (06-09-2024)“…Nanomedicines have created a paradigm shift in healthcare. Yet fundamental barriers still exist that prevent or delay the clinical translation of…”
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Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles
Published in International journal of molecular sciences (18-11-2017)“…Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of…”
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Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers
Published in Drug delivery and translational research (01-09-2022)“…State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes and several staining steps which can be affected by nanomaterial…”
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Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles
Published in Molecular pharmaceutics (07-08-2017)“…Protein adsorption on nanoparticles (NPs) used in nanomedicine leads to opsonization and activation of the complement system in blood, which substantially…”
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Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach
Published in International journal of pharmaceutics: X (01-12-2022)“…Poly (alkyl cyanoacrylate) (PACA) polymeric nanoparticles (NPs) are promising drug carriers in drug delivery. However, the selection of commercially available…”
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Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery
Published in Contrast media and molecular imaging (01-09-2015)“…Microbubbles (MBs) are routinely used as contrast agents for ultrasound imaging. The use of ultrasound in combination with MBs has also attracted attention as…”
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Nanoenabled Immunomodulatory Scaffolds for Cartilage Tissue Engineering
Published in Advanced functional materials (01-07-2024)“…Articular cartilage regeneration is a challenge in tissue engineering. Although diverse materials have been developed for this purpose, cartilage regeneration…”
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Preparation of polyurethane nanocapsules by miniemulsion polyaddition
Published in Journal of microencapsulation (01-01-2007)“…The encapsulation of organic liquids in polyurethane nanocapsules by interfacial miniemulsion polycondensation of isophorone diisocyanate and propanetriol has…”
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Sonopermeation to improve drug delivery to tumors: from fundamental understanding to clinical translation
Published in Expert opinion on drug delivery (02-12-2018)“…Ultrasound in combination with microbubbles can make cells and tissues more accessible for drugs, thereby achieving improved therapeutic outcomes. In this…”
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Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors
Published in Journal of controlled release (01-05-2023)“…K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic cancers and 20–25% of lung adenocarcinomas. The aim of this work was to…”
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On the issue of transparency and reproducibility in nanomedicine
Published in Nature nanotechnology (01-07-2019)“…Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds…”
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A multistep in vitro hemocompatibility testing protocol recapitulating the foreign body reaction to nanocarriers
Published in Drug delivery and translational research (01-09-2022)“…The development of drug nanocarriers based on polymeric, lipid and ceramic biomaterials has been paving the way to precision medicine, where the delivery of…”
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Effect of Radical Polymerization Method on Pharmaceutical Properties of Π Electron-Stabilized HPMA-Based Polymeric Micelles
Published in Biomacromolecules (09-10-2023)“…Polymeric micelles are among the most extensively used drug delivery systems. Key properties of micelles, such as size, size distribution, drug loading, and…”
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Subcellular detection of PEBCA particles in macrophages: combining darkfield microscopy, confocal Raman microscopy, and ToF–SIMS analysis
Published in Drug delivery and translational research (01-09-2022)“…The detection of biomedical organic nanocarriers in cells and tissues is still an experimental challenge. Here we developed an imaging strategy for the…”
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REFINE special issue
Published in Drug delivery and translational research (01-09-2022)Get full text
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A multi-step In Vitro Hemocompatibility Testing Protocol Recapitulating the Foreign Body Reaction to Nanocarriers
Published in Drug delivery and translational research (2022)“…The development of drug nanocarriers based on polymeric, lipidic and ceramic biomaterials has been paving the way to precision medicine where the delivery of…”
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