Search Results - "Schmelz, Monika"

The AIDS and Cancer Specimen Resource (ACSR): HIV malignancy specimens and data available at no cost by Silver, Sylvia, Schmelz, Monika

“…Abstract The goal of the AIDS and Cancer Specimen Resource (ACSR) is to play a major role in the advancement of HIV/AIDS cancer-related research/treatment by…”
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Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma by Kelly, Kevin R, Friedberg, Jonathan W, Park, Steven I, McDonagh, Kevin, Hayslip, John, Persky, Daniel, Ruan, Jia, Puvvada, Soham, Rosen, Peter, Iyer, Swaminathan Padmanabhan, Stefanovic, Alexandra, Bernstein, Steven H, Weitman, Steven, Karnad, Anand, Monohan, Gregory, VanderWalde, Ari, Mena, Raul, Schmelz, Monika, Spier, Catherine, Groshen, Susan, Venkatakrishnan, Karthik, Zhou, Xiaofei, Sheldon-Waniga, Emily, Leonard, E Jane, Mahadevan, Daruka

“…The aurora A kinase inhibitor alisertib demonstrated single-agent clinical activity and preclinical synergy with vincristine/rituximab in B-cell non-Hodgkin…”
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Pak2 regulates myeloid-derived suppressor cell development in mice by Zeng, Yi, Hahn, Seongmin, Stokes, Jessica, Hoffman, Emely A., Schmelz, Monika, Proytcheva, Maria, Chernoff, Jonathan, Katsanis, Emmanuel

“…Myeloid-derived suppressor cells (MDSCs) are CD11b+Gr1+ cells that induce T-cell hyporesponsiveness, thus impairing antitumor immunity. We have previously…”
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Lack and/or aberrant localization of major histocompatibility class II (MHCII) protein in plasmablastic lymphoma by SCHMELZ, Monika, MONTES-MORENO, Santiago, PIRIS, Miguel, WILKINSON, Sarah T, RIMSZA, Lisa M

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In vitro dorsal root ganglia and human prostate cell line interaction: Redefining perineural invasion in prostate cancer by Ayala, Gustavo E., Wheeler, Thomas M., Shine, H. David, Schmelz, Monika, Frolov, Ana, Chakraborty, Subhendu, Rowley, David

“…Background Little is understood regarding mechanisms of perineural invasion in prostate cancer progression. We present a novel model system and data that…”
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Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction by Thai, Hoang M, Juneman, Elizabeth, Lancaster, Jordan, Hagerty, Tracy, Do, Rose, Castellano, Lisa, Kellar, Robert, Williams, Stuart, Sethi, Gulshan, Schmelz, Monika, Gaballa, Mohamed, Goldman, Steven

“…This study was designed to determine if a viable biodegradable three-dimensional fibroblast construct (3DFC) patch implanted on the left ventricle after…”
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Prognostic Criteria for Squamous Cell Cancer of the Skin by Jensen, Vanessa, M.D, Prasad, Anil R., M.D, Smith, Aaron, M.D, Raju, Menaka, M.D, Wendel, Christopher S., M.S, Schmelz, Monika, Ph.D, Leyva, William, M.D, Warneke, James, M.D, Krouse, Robert S., M.D

“…Background Non-well-differentiated cutaneous squamous cell carcinomas may display a more aggressive behavior. It is important to better define prognostic…”
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Letter to the Editor: Validation of Biorepository Quality- Accreditation by Schmelz, Monika, Silver, Sylvia

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Cellular Immune Suppressor Activity Resides in Lymphocyte Cell Clusters Adjacent to Granulomata in Human Coccidioidomycosis by Li, Lijin, Dial, Sharon M, Schmelz, Monika, Rennels, Margaret A, Ampel, Neil M

“…The in situ immunologic response in human coccidioidomycosis remains undefined. To explore this further, pulmonary necrotizing coccidioidal granulomata were…”
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Biorepository best practices for research and clinical investigations by Sanderson-November, Micheline, Silver, Sylvia, Hooker, Vanessa, Schmelz, Monika

“…Translational research requires good quality specimens to ensure the integrity of research results. Clinical research must rely not only on quality specimens,…”
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Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells by Peitsch, Wiebke K., Grund, Christine, Kuhn, Caecilia, Schnölzer, Martina, Spring, Herbert, Schmelz, Monika, Franke, Werner W.

“…Using immunoblotting, immunprecipitation with subsequent fragment mass spectrometry, and immunolocalization techniques, we have detected the actin-binding ca…”
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Come in Out of the Cold: Alternatives to Freezing for Microbial Biorepositories by Isaacs, Erica, Schmelz, Monika

“…Abstract Biorepositories are “libraries” in which biospecimens, bacteria, or DNA and RNA extracts are stored for either clinical or research purposes. Such…”
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Optimizing assessment of CD30 expression in Hodgkin lymphoma by controlling for low expression by Sarwar, Shoib, Tome, Margaret E, Billheimer, Dean, Spier, Catherine, Smith, Catharine L, Persky, Daniel, Schmelz, Monika

“…Since the approval of brentuximab vedotin (BV), assessment of CD30 status by immunohistochemistry gained increasing importance in the clinical management of…”
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PEAZ-1: A new human prostate neoplastic epithelial cell line by Schmelz, Monika, Cress, Anne E., Barrera, Jean, McDaniel, Kathy M., Davis, Tracy L., Fuchs, Laura, Dalkin, Bruce L., Nagle, Raymond B.

“…BACKGROUND The generation of prostatic cell lines provides in vitro models for experimental studies of the pathogenesis of prostate carcinoma. Therefore, we…”
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A phase II study of belinostat (PXD101) in relapsed and refractory aggressive B-cell lymphomas: SWOG S0520 by Puvvada, Soham D., Li, Hongli, Rimsza, Lisa M., Bernstein, Steven H., Fisher, Richard I., LeBlanc, Michael, Schmelz, Monika, Glinsmann-Gibson, Betty, Miller, Thomas P., Maddox, Anne-Marie, Friedberg, Jonathan W., Smith, Sonali M., Persky, Daniel O.

“…Recent advances in diffuse large B-cell lymphomas (DLBCL) have underscored the importance of tumor microenvironment in escaping host anti-tumor responses. One…”
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Different Phenotypes in Human Prostate Cancer: α6 or α3 Integrin in Cell-extracellular Adhesion Sites by Schmelz, Monika, Cress, Anne E., Scott, Katherine M., Burger, Friederike, Cui, Haiyan, Sallam, Karim, McDaniel, Kathy M., Dalkin, Bruce L., Nagle, Raymond B.

“…The distribution of α6/α3 integrin in adhesion complexes at the basal membrane in human normal and cancer prostate glands was analyzed in 135 biopsies from 61…”
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Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma by Havas, Aaron P., Rodrigues, Kameron B., Bhakta, Anvi, Demirjian, Joseph A., Hahn, Seongmin, Tran, Jack, Scavello, Margarethakay, Tula-Sanchez, Ana A., Zeng, Yi, Schmelz, Monika, Smith, Catharine L.

“…Diffuse Large B-cell lymphoma (DLBCL) is an aggressive malignancy that has a 60 percent 5-year survival rate, highlighting a need for new therapeutic…”
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Differences of bcl-2 protein expression between Merkel cells and Merkel cell carcinomas by Moll, I, Gillardon, F, Waltering, S, Schmelz, M, Moll, R

“…The bcl-2 gene, originally identified in B-cell lymphomas, encodes for proteins which may assume oncogenic functions by blocking apoptosis. Bcl-2 proteins are…”
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A Phase II Exploratory Study of PXD-101 (Belinostat) Followed by Zevalin in Patients with Relapsed Aggressive High-Risk Lymphoma by Puvvada, Soham D, Guillén-Rodríguez, José M, Rivera, Xavier I, Heard, Kara, Inclan, Lora, Schmelz, Monika, Schatz, Jonathan H, Persky, Daniel O

“…Aggressive lymphomas (aNHL) including diffuse large B-cell lymphoma (DLBCL) have poor outcomes in relapsed refractory patients. Prior studies have demonstrated…”
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Aberrant cytoplasmic expression of MHCII confers worse progression free survival in diffuse large B-cell lymphoma by Kendrick, Samantha, Rimsza, Lisa M, Scott, David W, Slack, Graham W, Farinha, Pedro, Tan, King L, Persky, Daniel, Puvvada, Soham, Connors, Joseph M., Sehn, Laurie, Gascoyne, Randy D, Schmelz, Monika

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