Search Results - "Schmeling, David O. "
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Age-Specific Prevalence of Epstein-Barr Virus Infection Among Individuals Aged 6-19 Years in the United States and Factors Affecting Its Acquisition
Published in The Journal of infectious diseases (15-10-2013)“…Background. Data on the age-specific prevalence of Epstein-Barr virus (EBV) infection are relevant for determining when to administer a prophylactic vaccine…”
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2
The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity
Published in Immunity (Cambridge, Mass.) (25-07-2013)“…Immune cells sense microbial products through Toll-like receptors (TLR), which trigger host defense responses including type 1 interferons (IFNs) secretion. A…”
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3
The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events
Published in PLoS pathogens (01-12-2015)“…Epstein-Barr virus (EBV) is a human herpesvirus that causes acute infectious mononucleosis and is associated with cancer and autoimmune disease. While many…”
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4
Primary EBV infection induces an expression profile distinct from other viruses but similar to hemophagocytic syndromes
Published in PloS one (17-01-2014)“…Epstein-Barr Virus (EBV) causes infectious mononucleosis and establishes lifelong infection associated with cancer and autoimmune disease. To better understand…”
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5
A Prospective Clinical Study of Epstein‐Barr Virus and Host Interactions during Acute Infectious Mononucleosis
Published in The Journal of infectious diseases (01-11-2005)“…Background. Characterizing virus‐host interactions during self‐limited infectious mononucleosis could explain how Epstein‐Barr virus (EBV) replication is…”
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6
Cutting edge: NKG2C(hi)CD57+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus
Published in The Journal of immunology (1950) (15-05-2014)“…CMV induces the expansion of a unique subset of human NK cells expressing high levels of the activating CD94-NKG2C receptor that persist after control of the…”
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7
Behavioral, Virologic, and Immunologic Factors Associated With Acquisition and Severity of Primary Epstein-Barr Virus Infection in University Students
Published in The Journal of infectious diseases (01-01-2013)“…Background. University students were studied prospectively to determine the incidence of and risk factors for acquisition of primary Epstein-Barr virus (EBV)…”
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8
The promise of a prophylactic Epstein–Barr virus vaccine
Published in Pediatric research (01-01-2020)“…The worldwide burden of disease due to Epstein–Barr virus (EBV) infection is enormous. Diseases include endemic Burkitt lymphoma, infectious mononucleosis,…”
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9
A virologic pilot study of valacyclovir in infectious mononucleosis
Published in Journal of clinical virology (01-05-2007)“…Abstract Background Infectious mononucleosis decreases the productivity of many college students and Epstein–Barr virus (EBV) infection may result in long-term…”
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10
Rapid antibody responses to Epstein-Barr virus correlate with reduced severity of primary infection
Published in Journal of clinical virology (01-10-2022)“…•More rapid antibody responses in college freshmen who contracted a primary EBV infection.•during prospective surveillance correlated with a lower severity of…”
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The Impact of Donor Viral Replication at Transplant on Recipient Infections Posttransplant: A Prospective Study
Published in Transplantation (01-03-2015)“…BACKGROUNDOrgan donors are often implicated as the source of posttransplant recipient infection. We prospectively studied kidney and liver donor-recipient…”
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12
Primary Epstein-Barr virus infection does not erode preexisting CD8⁺ T cell memory in humans
Published in The Journal of experimental medicine (12-03-2012)“…Acute Epstein-Barr virus (EBV) infection results in an unusually robust CD8(+) T cell response in young adults. Based on mouse studies, such a response would…”
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13
Epstein-Barr Virus DNA in Parental Oral Secretions: A Potential Source of Infection for Their Young Children
Published in Clinical infectious diseases (07-01-2019)“…Epstein-Barr virus (EBV) DNA in parental oral secretions is a potential source of primary infection for children: 28% of parents were positive and prevalence…”
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14
Age-Specific Prevalence of Epstein-Barr Virus Infection Among Minnesota Children: Effects of Race/Ethnicity and Family Environment
Published in Clinical infectious diseases (15-08-2014)“…Background. Primary Epstein-Barr virus (EBV) infection affects the host differently according to when in life it is acquired. Understanding risk factors for…”
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15
Kinetics of Epstein-Barr Virus (EBV) Neutralizing and Virus-Specific Antibodies after Primary Infection with EBV
Published in Clinical and vaccine immunology (01-04-2016)“…Prospective studies of antibodies to multiple Epstein-Barr virus (EBV) proteins and EBV neutralizing antibodies in the same individuals before, during, and…”
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16
Valganciclovir Administration to Kidney Donors to Reduce the Burden of Cytomegalovirus and Epstein-Barr Virus Transmission During Transplantation
Published in Transplantation (01-06-2015)“…BACKGROUNDCytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are a significant cause of morbidity and mortality in transplant recipients and are…”
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17
Transplantation of solid organ recipients shedding Epstein‐Barr virus DNA pre‐transplant: A prospective study
Published in Clinical transplantation (01-11-2017)“…Epstein‐Barr virus (EBV) poses a significant threat to patient and graft survival post‐transplant. We hypothesized that recipients who shed EBV at transplant…”
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18
Prospective studies of infectious mononucleosis in university students
Published in Clinical & translational immunology (01-08-2016)“…We performed an intensive prospective study designed to obtain as much data as possible on the incubation and early illness periods of primary Epstein–Barr…”
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Epstein–Barr virus dynamics in asymptomatic immunocompetent adults: an intensive 6‐month study
Published in Clinical & translational immunology (13-05-2016)“…Characterizing Epstein–Barr virus (EBV) dynamics in asymptomatic immunocompetent persons provides a baseline for defining quantitative thresholds associated…”
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The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events: e1005286
Published in PLoS pathogens (01-12-2015)“…Epstein-Barr virus (EBV) is a human herpesvirus that causes acute infectious mononucleosis and is associated with cancer and autoimmune disease. While many…”
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