Search Results - "Schmaljohn, C.S."
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Development and application of a flow cytometric potency assay for DNA vaccines
Published in Vaccine (09-09-2011)“…Abstract We have developed a rapid, reliable, and sensitive quantitative flow cytometric assay to measure the in vitro potency and stability of DNA vaccines to…”
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A Lethal Disease Model for Hantavirus Pulmonary Syndrome
Published in Virology (New York, N.Y.) (10-10-2001)“…Hantaviruses are associated with two human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Development of…”
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DNA Vaccination with Vaccinia Virus L1R and A33R Genes Protects Mice against a Lethal Poxvirus Challenge
Published in Virology (New York, N.Y.) (20-01-2000)“…Previously we found that passive transfer of monoclonal antibodies (MAbs) specific to either the vaccinia virus (VACV) L1R or A33R gene product protected mice…”
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Journal Article -
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DNA Vaccination with Hantavirus M Segment Elicits Neutralizing Antibodies and Protects against Seoul Virus Infection
Published in Virology (New York, N.Y.) (15-03-1999)“…Seoul virus (SEOV) is one of four known hantaviruses causing hemorrhagic fever with renal syndrome (HFRS). Candidate naked DNA vaccines for HFRS were…”
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Andes virus M genome segment is not sufficient to confer the virulence associated with Andes virus in Syrian hamsters
Published in Virology (New York, N.Y.) (15-08-2004)“…Sin Nombre virus (SNV) and Andes virus (ANDV), members of the genus Hantavirus, in the family Bunyaviridae, are causative agents of hantavirus pulmonary…”
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Comparison of the Protective Efficacy of Naked DNA, DNA-based Sindbis Replicon, and Packaged Sindbis Replicon Vectors Expressing Hantavirus Structural Genes in Hamsters
Published in Virology (New York, N.Y.) (10-10-1999)“…Seoul virus (SEOV) is a member of the Hantavirus genus (family Bunyaviridae) and an etiological agent of hemorrhagic fever with renal syndrome. The medium (M)…”
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Journal Article -
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Nucleotide sequence of the L genome segment of hantaan virus
Published in Nucleic acids research (25-11-1990)“…The L genome segment of Hantaan virus was found to consist of 6,530 nucleotides. A hard copy of the sequence can be obtained from the author with requests for…”
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Epitope mapping studies with neutralizing and non-neutralizing monoclonal antibodies to the G1 and G2 envelope glycoproteins of Hantaan virus
Published in Virology (New York, N.Y.) (01-12-1993)“…Epitopes recognized by three G1-specific and two G2-specific neutralizing monoclonal antibodies to Hantaan virus were mapped by sequence analyses of the…”
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Antigenic and Genetic Properties of Viruses Linked to Hemorrhagic Fever with Renal Syndrome
Published in Science (American Association for the Advancement of Science) (01-03-1985)“…Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic…”
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Characterization of Langat virus antigenic determinants defined by monoclonal antibodies to E, NS1 and preM and identification of a protective, non-neutralizing preM-specific monoclonal antibody
Published in Virus research (01-08-1996)“…Hybridomas secreting monoclonal antibodies (MAb) to the thick-borne encephalitis (TBE) group virus, Langat virus (LGTV), were prepared. Of more than 200 MAb…”
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Journal Article -
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Preparation of candidate vaccinia-vectored vaccines for haemorrhagic fever with renal syndrome
Published in Vaccine (1992)“…Two vaccinia-vectored candidate vaccines for haemorrhagic fever with renal syndrome were prepared by inserting cDNA, representing the medium (M) genome…”
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Baculovirus expression of the M genome segment of Rift Valley fever virus and examination of antigenic and immunogenic properties of the expressed proteins
Published in Virology (New York, N.Y.) (01-05-1989)“…Autographa californica nuclear polyhedrosis viral recombinants containing coding information for the Rift Valley fever virus (RVFV) envelope glycoproteins (G1…”
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Partial nucleotide sequence of the Japanese encephalitis virus genome
Published in Virology (New York, N.Y.) (01-06-1987)“…Approximately 10 kb of the estimated 10.9-kb genome of the Japanese encephalitis virus (JE; Nakayama strain) has been cloned as cDNA; the uncloned portion…”
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A colorimetric PCR-enzyme immunoassay to identify hantaviruses
Published in Clinical and diagnostic virology (01-08-1997)“…Background: Hantaviruses cause two serious human diseases: hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome. At least nine hantaviruses…”
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