Search Results - "Schmähl, D"

Cisplatin-linked phosphonates in the treatment of the transplantable osteosarcoma in vitro and in vivo by Klenner, T, Valenzuela-Paz, P, Keppler, B K, Angres, G, Scherf, H R, Wingen, F, Amelung, F, Schmähl, D

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Influence of reducing luxury calories in the treatment of experimental mammary carcinoma by BUNK, B, ZHU, P, BERGER, M. R, SCHMÄHL, D

“…The aim of this study was to investigate the influence of dietary calorie intake at three different fat levels on (a) the growth of established…”
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Nitrosamine-induced carcinogenesis: experimental models for human malignancies of multifactorial origin by Schmähl, D

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Carcinogenicity of anticancer drugs and especially alkylating agents by Schmähl, D

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Carcinogenicity of N-nitrosodiethanolamine in rats at five different dose levels by Preussmann, R, Habs, M, Habs, H, Schmähl, D

“…N-nitrosodiethanolamine, an N-nitroso compound of environmental significance, has been tested for carcinogenicity in male Sprague-Dawley rats at five different…”
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Combination effects in chemical carcinogenesis by Schmähl, D

“…Only very few malignant tumors in human beings can be attributed to one single chemical substance. Therefore, combination effects are of particular practical…”
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Occurrence of second tumors in man after anticancer drug treatment by Schmähl, D, Habs, M, Lorenz, M, Wagner, I

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Therapeutic efficacy of two different cytostatic-linked phosphonates in combination with razoxane in the transplantable osteosarcoma of the rat by Klenner, T, Wingen, F, Keppler, B, Valenzuela-Paz, P, Amelung, F, Schmähl, D

“…Two new compounds, 4-[4-[bis-(2-chloroethyl)-amino-]phenyl]-1- hydroxybutane-1,1-bisphosphonic acid (BAD) and…”
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Reduction of carcinogenicity of N-nitrosomethylurea by indomethacin and failure of resuming effect of prostaglandin E2 (PGE2) against indomethacin by NARISAWA, T, HERMANEK, P, HABS, M, SCHMÄHL, D

“…Nonsteroid antiinflammatory drugs such as indomethacin may play an important role in preventing the development of chemically induced experimental carcinomas…”
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Anticancer activity of bisphosphonic acids in methylnitrosourea-induced mammary carcinoma of the rat ― benefit of combining bisphosphonates with cytostatic agents by WINGEN, F, POOL, B. L, KLEIN, P, KLENNER, T, SCHMÄHL, D

“…This study primarily describes the cytostatic activity of a bisphosphonate and of an alkylating agent linked bisphosphonate toward mammary carcinomas in vivo…”
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The initiator tRNA acceptance assay as a short-term test for carcinogens. 5. Results with 42 cytostatic drugs by Hradec, J, Osswald, H, Beth, M, Schmähl, D

“…The activity of 42 cytostatic drugs used for the treatment of human cancer was tested by the initiator tRNA acceptance assay for carcinogens. Of 17 drugs…”
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Long-term carcinogenicity of cyclophosphamide in two mouse strains with different spontaneous leukemia incidence by Petru, E, Berger, M R, Schmähl, D

“…The aim of the present study was to investigate to what extent the induction of leukemia by the carcinogenic agent cyclophosphamide (CPA) might be influenced…”
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Relationship between dose and risk reduction: statistical evaluation of a combination experiment with three hepatocarcinogenic N-nitrosamines in rats by Berger, M R, Schmähl, D, Edler, L

“…Data from an experiment on the single and combination effects of very low doses of N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR) and…”
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Anticancer efficacy of 2-chloroethylnitrosocarbamoyl derivatives of L-alanine, glycine, their di- and tripeptide homologues and the respective amides in methylnitrosourea-induced rat mammary carcinoma by KLENNER, T, BERGER, M. R, EISENBRAND, G, SCHMÄHL, D

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Syncarcinogenesis at low exposure levels of three nitrosamines with a common target of carcinogenic action: preliminary results by Berger, M R, Schmähl, D

“…The carcinogenic activities of N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR) and N-nitrosodiethanolamine (NDELA) and of the combination of the…”
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Comparison of human and rodent response to genotoxicants by Schmähl, D F, Schmezer, P

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Carcinogenicity of 1-(4-amino-2-methylpyrimidine-5-yl)-methyl-3-(2-chloroethyl)-3- nitrosoureahydrochloride and three related N-nitroso derivatives following repeated intravenous administration to male Wistar rats by Berger, M R, Petru, E, Schmähl, D

“…Long-term toxic evaluation of 1-(4-amino-2-methylpyrimidine-5-yl)-methyl-3- (2-chloroethyl)-3-nitrosoureahydrochloride (ACNU),…”
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Multiple environmental carcinogens: their significance by Schmähl, D

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Carcinogenicity of alkylating cytostatic drugs: conclusions and directions for future research by Kaldor, J, Schmähl, D

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Technique for long-term infusion into the inferior mesenteric artery of unrestrained rats by Aguiar, J.L.A, Garzon, F.T, Schneider, S, Berger, M.R, Schlag, P, Schmahl, D

“…A technique for long-term infusion into the inferior mesenteric artery was developed which allows simple and reliable regional infusion into the colorectal…”
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