Search Results - "Schlottmann, Inga"
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Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis
Published in Annals of the rheumatic diseases (01-04-2013)“…Epigenetic modifications such as DNA methylation and histone acetylation have been implicated in the pathogenesis of systemic sclerosis. However, histone…”
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Journal Article -
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The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis
Published in Annals of the rheumatic diseases (01-06-2014)“…Activated Wnt signalling with decreased expression of endogenous inhibitors has recently been characterised as a central pathomechanism in systemic sclerosis…”
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Journal Article