Search Results - "Schlossmann, J."

Function of cGMP-Dependent Protein Kinases as Revealed by Gene Deletion by Hofmann, F, Feil, R, Kleppisch, T, Schlossmann, J

“…Institut für Pharmakologie und Toxikologie, TU München, München, Germany Over the past few years, a wealth of biochemical and functional data have been…”
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Levels and activity of cyclic guanosine monophosphate‐dependent protein kinase in nurse and forager honeybees by Thamm, M., Sturm, K., Schlossmann, J., Scheiner, R.

“…Age‐dependent division of labour in honeybees was shown to be connected to sensory response thresholds. Foragers show a higher gustatory responsiveness than…”
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Distribution of IRAG and cGKI-isoforms in murine tissues by Geiselhöringer, A., Gaisa, M., Hofmann, F., Schlossmann, J.

“…cGMP kinase I (cGKI) signaling modulates multiple physiological processes including smooth muscle relaxation. The expression of cGKI and its substrate IRAG ( I…”
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Distribution of cGMP-dependent protein kinase type I and its isoforms in the mouse brain and retina by Feil, S., Zimmermann, P., Knorn, A., Brummer, S., Schlossmann, J., Hofmann, F., Feil, R.

“…Nitric oxide (NO) modulates a variety of processes in the mammalian brain, but the mechanisms of neuronal NO signaling are poorly understood. In the periphery,…”
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Specific recognition of mitochondrial preproteins by the cytosolic domain of the import receptor MOM72 by Schlossmann, J, Dietmeier, K, Pfanner, N, Neupert, W

“…The import receptor MOM72 constitutes part of the protein translocation machinery of the outer mitochondrial membrane, the receptor-general insertion pore…”
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Assembly of the Preprotein Receptor MOM72/MAS70 into the Protein Import Complex of the Outer Membrane of Mitochondria () by Schlossmann, Jens, Neupert, Walter

“…Membrane integration and assembly of MOM72 from Neurospora crassa and its yeast homolog MAS70 was studied with isolated mitochondria. After synthesis in vitro,…”
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Insights into cGMP signalling derived from cGMP kinase knockout mice by Schlossmann, Jens, Feil, Robert, Hofmann, Franz

“…cGMP signalling plays an important physiological role in diverse organs including the vasculature, the GI-tract and the nervous system. Furthermore,…”
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Rising behind NO: cGMP-dependent protein kinases by Hofmann, F, Ammendola, A, Schlossmann, J

“…Over the past few years, a wealth of biochemical and functional data has been gathered on mammalian cGMP-dependent protein kinases (cGKs). In mammals, three…”
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cGMP-dependent protein kinases in drug discovery by Schlossmann, Jens, Hofmann, Franz

“…cGMP-dependent protein kinases and their downstream targets are important for cardiovascular, gastrointestinal and neuronal function and are valuable for…”
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Signaling through NO and cGMP-dependent protein kinases by Schlossmann, Jens, Feil, Robert, Hofmann, Franz

“…The gaseous molecule nitric oxide (NO) modulates a large variety of physiological functions including vascular tone, intestinal motility, platelet aggregation,…”
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Targeting and translocation of the phosphate carrier/p32 to the inner membrane of yeast mitochondria by Dietmeier, K, Zara, V, Palmisano, A, Palmieri, F, Voos, W, Schlossmann, J, Moczko, M, Kispal, G, Pfanner, N

“…We analyzed the submitochondrial location and biogenesis pathway of the phosphate carrier (PiC), also termed p32, of Saccharomyces cerevisiae mitochondria,…”
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Iron deficiency anemia in cyclic GMP kinase knockout mice by Angermeier, Elisabeth, Domes, Katrin, Lukowski, Robert, Schlossmann, Jens, Rathkolb, Birgit, Angelis, Martin Hraběde, Hofmann, Franz

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Molecular Determinants of the Interaction between the Inositol 1,4,5-Trisphosphate Receptor-associated cGMP Kinase Substrate (IRAG) and cGMP Kinase Iβ by Ammendola, Aldo, Geiselhöringer, Angela, Hofmann, Franz, Schlossmann, Jens

“…Cyclic GMP-dependent protein kinase I (cGKI) affects the inositol 1,4,5-trisphosphate (InsP sub(3))-dependent release of intracellular calcium by…”
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Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ by SCHLOSSMANN, J, AMMENDOLA, A, HOFMANN, F, RUTH, P, ASHMAN, K, XIANGANG ZONG, HUBER, A, NEUBAUER, G, WANG, G.-X, ALLESCHER, H.-D, KORTH, M, WLLM, M

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IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase by Geiselhöringer, Angela, Werner, Matthias, Sigl, Katja, Smital, Petra, Wörner, René, Acheo, Linda, Stieber, Juliane, Weinmeister, Pascal, Feil, Robert, Feil, Susanne, Wegener, Jörg, Hofmann, Franz, Schlossmann, Jens

“…Signalling by cGMP‐dependent protein kinase type I (cGKI) relaxes various smooth muscles modulating thereby vascular tone and gastrointestinal motility…”
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Functional Reconstitution of Vascular Smooth Muscle Cells With cGMP-Dependent Protein Kinase I Isoforms by Feil, Robert, Gappa, Nicolai, Rutz, Mark, Schlossmann, Jens, Rose, Christine R, Konnerth, Arthur, Brummer, Sabine, Kühbandner, Susanne, Hofmann, Franz

“…The cGMP-dependent protein kinase type I (cGKI) is a major mediator of NO/cGMP-induced vasorelaxation. Smooth muscle expresses two isoforms of cGKI, cGKIα and…”
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Association of phospholamban with a cGMP kinase signaling complex by Koller, Angela, Schlossmann, Jens, Ashman, Keith, Uttenweiler-Joseph, Sandrine, Ruth, Peter, Hofmann, Franz

“…The cGMP kinase signaling complex identified previously in tracheal smooth muscle membranes contains a number of cGMP kinase substrates termed G0 through G4…”
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Protein Phosphatase 2A Is Essential for the Activation of Ca2+-activated K+ Currents by cGMP-dependent Protein Kinase in Tracheal Smooth Muscle and Chinese Hamster Ovary Cells by Zhou, Xiao-Bo, Ruth, Peter, Schlossmann, Jens, Hofmann, Franz, Korth, Michael

“…The regulation of Ca2+-activated K+ channels (KCa channels) by cGMP-dependent protein kinase (cGMP kinase) and its molecular mechanism were investigated in…”
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Neutrophil Dysfunction in Guanosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase I-Deficient Mice by Werner, Claudia G, Godfrey, Virginia, Arnold, Roland R, Featherstone, Gerald L, Bender, Diane, Schlossmann, Jens, Schiemann, Matthias, Hofmann, Franz, Pryzwansky, Katherine B

“…The regulation of neutrophil functions by Type I cGMP-dependent protein kinase (cGKI) was investigated in wild-type (WT) and cGKI-deficient (cGKI-/-) mice. We…”
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Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca super(2+)-activated K super(+) channel by Sausbier, M, Zhou, X-B, Beier, C, Sausbier, U, Wolpers, D, Maget, S, Martin, C, Dietrich, A, Ressmeyer, A-R, Renz, H, Schlossmann, J, Hofmann, F, Neuhuber, W, Gudermann, T

“…The unique voltage- and Ca super(2+)-dependent K super(+) (BK) channel, prominently expressed in airway smooth muscle cells, has been suggested as an important…”
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