Search Results - "Schlossmacher, Ute"

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells by Wiens, Matthias, Wang, Xiaohong, Schröder, Heinz C, Kolb, Ute, Schloßmacher, Ute, Ushijima, Hiroshi, Müller, Werner E.G

“…Abstract Earlier studies have demonstrated that biosilica, synthesized by the enzyme silicatein, induces hydroxyapatite formation in osteoblast-like SaOS-2…”
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Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca²⁺ level in osteoblasts (SaOS-2 cells) in vitro by Müller, Werner E.G, Wang, Xiaohong, Diehl-Seifert, Bärbel, Kropf, Klaus, Schloßmacher, Ute, Lieberwirth, Ingo, Glasser, Gunnar, Wiens, Matthias, Schröder, Heinz C

“…Inorganic polymeric phosphate is a physiological polymer that accumulates in bone cells. In the present study osteoblast-like SaOS-2 cells were exposed to this…”
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Osteogenic Potential of Biosilica on Human Osteoblast-Like (SaOS-2) Cells by Wiens, Matthias, Wang, Xiaohong, Schloßmacher, Ute, Lieberwirth, Ingo, Glasser, Gunnar, Ushijima, Hiroshi, Schröder, Heinz C., Müller, Werner E. G.

“…Biosilica is a natural polymer, synthesized by the poriferan enzyme silicatein from monomeric silicate substrates. Biosilica stimulates mineralizing activity…”
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Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber‐like spicules by Wang, Xiaohong, Schloßmacher, Ute, Wiens, Matthias, Batel, Renato, Schröder, Heinz C., Müller, Werner E. G.

“…Biomineralization processes are characterized by controlled deposition of inorganic polymers/minerals mediated by functional groups linked to organic…”
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Sponge spicules as blueprints for the biofabrication of inorganic-organic composites and biomaterials by Müller, Werner E. G, Wang, Xiaohong, Cui, Fu-Zhai, Jochum, Klaus Peter, Tremel, Wolfgang, Bill, Joachim, Schröder, Heinz C, Natalio, Filipe, Schloßmacher, Ute, Wiens, Matthias

“…While most forms of multicellular life have developed a calcium-based skeleton, a few specialized organisms complement their body plan with silica. However, of…”
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The marine sponge-derived inorganic polymers, biosilica and polyphosphate, as morphogenetically active matrices/scaffolds for the differentiation of human multipotent stromal cells: potential application in 3D printing and distraction osteogenesis by Wang, Xiaohong, Schröder, Heinz C, Grebenjuk, Vladislav, Diehl-Seifert, Bärbel, Mailänder, Volker, Steffen, Renate, Schloßmacher, Ute, Müller, Werner E G

“…The two marine inorganic polymers, biosilica (BS), enzymatically synthesized from ortho-silicate, and polyphosphate (polyP), a likewise enzymatically…”
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Induction of carbonic anhydrase in SaOS-2 cells, exposed to bicarbonate and consequences for calcium phosphate crystal formation by Müller, Werner E.G, Schröder, Heinz C, Schlossmacher, Ute, Grebenjuk, Vlad A, Ushijima, Hiroshi, Wang, Xiaohong

“…Abstract Ca-phosphate/hydroxyapatite crystals constitute the mineralic matrix of vertebrate bones, while Ca-carbonate dominates the inorganic matrix of…”
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Evagination of cells controls bio-silica formation and maturation during spicule formation in sponges by Wang, Xiaohong, Wiens, Matthias, Schröder, Heinz C, Schlossmacher, Ute, Pisignano, Dario, Jochum, Klaus Peter, Müller, Werner E G

“…The enzymatic-silicatein mediated formation of the skeletal elements, the spicules of siliceous sponges starts intracellularly and is completed…”
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Common genetic denominators for Ca++-based skeleton in Metazoa: role of osteoclast-stimulating factor and of carbonic anhydrase in a calcareous sponge by Müller, Werner E G, Wang, Xiaohong, Grebenjuk, Vlad A, Korzhev, Michael, Wiens, Matthias, Schlossmacher, Ute, Schröder, Heinz C

“…Calcium-based matrices serve predominantly as inorganic, hard skeletal systems in Metazoa from calcareous sponges [phylum Porifera; class Calcarea] to proto-…”
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Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber‐like spicules by Wang, Xiaohong, Schloßmacher, Ute, Wiens, Matthias, Batel, Renato, Schröder, Heinz C., Müller, Werner E. G.

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Silintaphin-1 - interaction with silicatein during structure-guiding bio-silica formation by Schloßmacher, Ute, Wiens, Matthias, Schröder, Heinz C, Wang, Xiaohong, Jochum, Klaus P, Müller, Werner E.G

“…Silicateins are unique enzymes of sponges (phylum Porifera) that template and catalyze the polymerization of nanoscale silicate to siliceous skeletal elements…”
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Bioorganic/inorganic hybrid composition of sponge spicules: Matrix of the giant spicules and of the comitalia of the deep sea hexactinellid Monorhaphis by Müller, Werner E.G., Wang, Xiaohong, Kropf, Klaus, Ushijima, Hiroshi, Geurtsen, Werner, Eckert, Carsten, Tahir, Muhammad Nawaz, Tremel, Wolfgang, Boreiko, Alexandra, Schloßmacher, Ute, Li, Jinhe, Schröder, Heinz C.

“…The giant basal spicules of the siliceous sponges Monorhaphis chuni and Monorhaphis intermedia (Hexactinellida) represent the largest biosilica structures on…”
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Silicatein expression in the hexactinellid Crateromorpha meyeri: the lead marker gene restricted to siliceous sponges by Müller, Werner E. G., Wang, Xiaohong, Kropf, Klaus, Boreiko, Alexandra, Schloßmacher, Ute, Brandt, David, Schröder, Heinz C., Wiens, Matthias

“…The siliceous spicules of sponges (Porifera) are synthesized by the enzyme silicatein. This protein and its gene have been identified so far in the…”
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Bio-sintering processes in hexactinellid sponges: Fusion of bio-silica in giant basal spicules from Monorhaphis chuni by Müller, Werner E.G., Wang, Xiaohong, Burghard, Zaklina, Bill, Joachim, Krasko, Anatoli, Boreiko, Alexandra, Schloßmacher, Ute, Schröder, Heinz C., Wiens, Matthias

“…The two sponge classes, Hexactinellida and Demospongiae, comprise a skeleton that is composed of siliceous skeletal elements (spicules). Spicule growth…”
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Hardening of bio-silica in sponge spicules involves an aging process after its enzymatic polycondensation: Evidence for an aquaporin-mediated water absorption by Müller, Werner E.G., Wang, Xiaohong, Wiens, Matthias, Schloßmacher, Ute, Jochum, Klaus Peter, Schröder, Heinz C.

“…Spicules, the siliceous skeletal elements of the siliceous sponges, are synthesized enzymatically via silicatein. The product formed, bio-silica, constitutes…”
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Dual effect of inorganic polymeric phosphate/polyphosphate on osteoblasts and osteoclasts in vitro by Wang, Xiaohong, Schröder, Heinz C., Diehl-Seifert, Bärbel, Kropf, Klaus, Schlossmacher, Ute, Wiens, Matthias, Müller, Werner E. G.

“…Inorganic polymeric phosphate/polyphosphate (polyP) is a natural polymer existing in both pro‐ and eukaryotic systems. In the present study the effect of polyP…”
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Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) by Müller, Werner E.G, Schloßmacher, Ute, Wang, Xiaohong, Boreiko, Alexandra, Brandt, David, Wolf, Stephan E, Tremel, Wolfgang, Schröder, Heinz C

“…Siliceous sponges can synthesize poly(silicate) for their spicules enzymatically using silicatein. We found that silicatein exists in silica-filled cell…”
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The silicatein propeptide acts as inhibitor/modulator of self‐organization during spicule axial filament formation by Müller, Werner E. G., Schröder, Heinz C., Muth, Sandra, Gietzen, Sabine, Korzhev, Michael, Grebenjuk, Vlad A., Wiens, Matthias, Schloßmacher, Ute, Wang, Xiaohong

“…Silicateins are crucial enzymes that are involved in formation of the inorganic biosilica scaffold of the spicular skeleton of siliceous sponges. We show that…”
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Acquisition of Structure-guiding and Structure-forming Properties during Maturation from the Pro-silicatein to the Silicatein Form by Schröder, Heinz C., Wang, Xiaohong, Manfrin, Alberto, Yu, Shu-Hong, Grebenjuk, Vlad A., Korzhev, Michael, Wiens, Matthias, Schlossmacher, Ute, Müller, Werner E.G.

“…Silicateins are the key enzymes involved in the enzymatic polycondensation of the inorganic scaffold of the skeletal elements of the siliceous sponges, the…”
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Formation of giant spicules in the deep-sea hexactinellid Monorhaphis chuni (Schulze 1904): electron-microscopic and biochemical studies by Müller, Werner E G, Eckert, Carsten, Kropf, Klaus, Wang, Xiaohong, Schlossmacher, Ute, Seckert, Christopf, Wolf, Stephan E, Tremel, Wolfgang, Schröder, Heinz C

“…The siliceous sponge Monorhaphis chuni (Hexactinellida) synthesizes the largest biosilica structures on earth (3 m). Scanning electron microscopy has shown…”
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