Search Results - "Schlievert, Patrick"

Models matter: the search for an effective Staphylococcus aureus vaccine by Salgado-Pabón, Wilmara, Schlievert, Patrick M.

“…The development of a vaccine against Staphylococcus aureus infection has been the subject of an intensive research effort, but none of the vaccine trials has…”
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Glycerol monolaurate antibacterial activity in broth and biofilm cultures by Schlievert, Patrick M, Peterson, Marnie L

“…Glycerol monolaurate (GML) is an antimicrobial agent that has potent activity against gram-positive bacteria. This study examines GML antibacterial activity in…”
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Device-Associated Menstrual Toxic Shock Syndrome by Schlievert, Patrick M, Davis, Catherine C

“…In the 1980s, menstrual toxic shock syndrome (mTSS) became a household topic, particularly among mothers and their daughters. The research performed at the…”
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Effect of non-absorbent intravaginal menstrual/contraceptive products on Staphylococcus aureus and production of the superantigen TSST-1 by Schlievert, Patrick M.

“…Tampons are associated with toxic shock syndrome (mTSS). One reason for this association is oxygen introduction within tampons into the anaerobic vagina…”
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The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression by Crosby, Heidi A, Schlievert, Patrick M, Merriman, Joseph A, King, Jessica M, Salgado-Pabón, Wilmara, Horswill, Alexander R

“…Staphylococcus aureus is a human commensal and opportunistic pathogen that causes devastating infections in a wide range of locations within the body. One of…”
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Staphylococcal and Streptococcal Superantigen Exotoxins by Spaulding, Adam R, Salgado-Pabón, Wilmara, Kohler, Petra L, Horswill, Alexander R, Leung, Donald Y M, Schlievert, Patrick M

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics by DeVries, Aaron S, Lesher, Lindsey, Schlievert, Patrick M, Rogers, Tyson, Villaume, Lourdes G, Danila, Richard, Lynfield, Ruth

“…Circulating strains of Staphylococcus aureus (SA) have changed in the last 30 years including the emergence of community-associated methicillin-resistant SA…”
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Glycerol Monolaurate Contributes to the Antimicrobial and Anti-inflammatory Activity of Human Milk by Schlievert, Patrick M., Kilgore, Samuel H., Seo, Keun Seok, Leung, Donald Y. M.

“…Human milk has antimicrobial compounds and immunomodulatory activities. We investigated glycerol monolaurate (GML) in human milk versus bovine milk and infant…”
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Probable enterotoxin-associated toxic shock syndrome caused by Staphylococcus epidermidis by Pomputius, William F, Kilgore, Samuel H, Schlievert, Patrick M

“…We describe a case of a toxic shock-like syndrome in a child, which was associated with Staphylococcus epidermidis instead of Staphylococcus aureus or…”
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Gram‐positive bacterial superantigen outside‐in signaling causes toxic shock syndrome by Brosnahan, Amanda J., Schlievert, Patrick M.

“…Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐positive pathogens capable of producing a variety of bacterial exotoxins known…”
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Semen Exosomes Promote Transcriptional Silencing of HIV-1 by Disrupting NF-κB/Sp1/Tat Circuitry by Welch, Jennifer L, Kaddour, Hussein, Schlievert, Patrick M, Stapleton, Jack T, Okeoma, Chioma M

“…Exosomes play various roles in host responses to cancer and infective agents, and semen exosomes (SE) inhibit HIV-1 infection and transmission, although the…”
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Kawasaki syndrome: role of superantigens revisited by Leung, Donald Y. M., Schlievert, Patrick M.

“…Kawasaki syndrome and toxic shock syndrome are ‘cytokine storms’ that result in overlapping clinical features due to vasculitis associated with massive…”
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Non-aqueous glycerol monolaurate gel exhibits antibacterial and anti-biofilm activity against Gram-positive and Gram-negative pathogens by Mueller, Elizabeth A, Schlievert, Patrick M

“…Skin and surgical infections due to Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii are causes of patient morbidity and increased…”
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A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia by Wilson, Gillian J, Seo, Keun Seok, Cartwright, Robyn A, Connelley, Timothy, Chuang-Smith, Olivia N, Merriman, Joseph A, Guinane, Caitriona M, Park, Joo Youn, Bohach, Gregory A, Schlievert, Patrick M, Morrison, W Ivan, Fitzgerald, J Ross

“…Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus…”
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The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization by Salimi, Hamid, Johnson, Jacklyn, Flores, Manuel G., Zhang, Michael S., O'Malley, Yunxia, Houtman, Jon C., Schlievert, Patrick M., Haim, Hillel

“…The envelope glycoproteins (Envs) of HIV-1 are embedded in the cholesterol-rich lipid membrane of the virus. Chemical depletion of cholesterol from HIV-1…”
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Staphylococcal Enterotoxin B and C Mutants and Vaccine Toxoids by Schlievert, Patrick M

“…Three mutants individually of both staphylococcal enterotoxins B and C were prepared by site-specific mutagenesis of enterotoxin amino acids that contact host…”
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Novel Tissue Level Effects of the Staphylococcus aureus Enterotoxin Gene Cluster Are Essential for Infective Endocarditis by Stach, Christopher S, Vu, Bao G, Merriman, Joseph A, Herrera, Alfa, Cahill, Michael P, Schlievert, Patrick M, Salgado-Pabón, Wilmara

“…Superantigens are indispensable virulence factors for Staphylococcus aureus in disease causation. Superantigens stimulate massive immune cell activation,…”
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Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus , and its relevance to atopic dermatitis by Schlievert, Patrick M., PhD, Strandberg, Kristi L., PhD, Lin, Ying-Chi, MS, Peterson, Marnie L., PharmD, PhD, Leung, Donald Y.M., MD, PhD

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains have emerged as serious health threats in the last 15 years. They are…”
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Glycerol Monolaurate, an Analogue to a Factor Secreted by Lactobacillus , Is Virucidal against Enveloped Viruses, Including HIV-1 by Welch, Jennifer L, Xiang, Jinhua, Okeoma, Chioma M, Schlievert, Patrick M, Stapleton, Jack T

“…The vaginal microbiota influences sexual transmission of human immunodeficiency virus type 1 (HIV-1). Colonization of the vaginal tract is normally dominated…”
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The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function by Tuffs, Stephen W, James, David B A, Bestebroer, Jovanka, Richards, Amy C, Goncheva, Mariya I, O'Shea, Marie, Wee, Bryan A, Seo, Keun Seok, Schlievert, Patrick M, Lengeling, Andreas, van Strijp, Jos A, Torres, Victor J, Fitzgerald, J Ross

“…Bacterial superantigens (SAgs) cause Vβ-dependent T-cell proliferation leading to immune dysregulation associated with the pathogenesis of life-threatening…”
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