Search Results - "Schliefsteiner, Carolin"

Placental Hofbauer Cell Polarization Resists Inflammatory Cues In Vitro by Schliefsteiner, Carolin, Ibesich, Sandra, Wadsack, Christian

“…Feto-placental Hofbauer cells (HBCs) are macrophages residing in placental stroma. They are generally described as anti-inflammatory M2 polarized cells,…”
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Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia by Mercnik, Monika Horvat, Schliefsteiner, Carolin, Fluhr, Herbert, Wadsack, Christian

“…Hofbauer cells (HBCs) are resident macrophages of the human placenta, regulating immune tolerance and tissue homeostasis. HBCs of a normal placenta (CTR)…”
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Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus by Schliefsteiner, Carolin, Peinhaupt, Miriam, Kopp, Susanne, Lögl, Jelena, Lang-Olip, Ingrid, Hiden, Ursula, Heinemann, Akos, Desoye, Gernot, Wadsack, Christian

“…Hofbauer cells (HBCs) are macrophages of the feto-placental unit. Despite the general view that these cells have an anti-inflammatory M2 phenotype, recent…”
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The Distinct Role of the HDL Receptor SR-BI in Cholesterol Homeostasis of Human Placental Arterial and Venous Endothelial Cells by Strahlhofer-Augsten, Manuela, Schliefsteiner, Carolin, Cvitic, Silvija, George, Meekha, Lang-Olip, Ingrid, Hirschmugl, Birgit, Marsche, Gunther, Lang, Uwe, Novakovic, Boris, Saffery, Richard, Desoye, Gernot, Wadsack, Christian

“…As opposed to adults, high-density lipoprotein (HDL) is the main cholesterol carrying lipoprotein in fetal circulation. The major HDL receptor, scavenger…”
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Unlocking the secrets of Hofbauer cells in placental (patho-) physiology: Isolation and quality assessment in human term placenta by Mercnik, Monika Horvat, Wadsack, Christian, Schliefsteiner, Carolin

“…Hofbauer cells (HBCs) are macrophages of fetal origin that reside in the villous tissue. They are the only immune cells within healthy villi. While HBCs…”
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TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancy by Horvat Mercnik, Monika, Schliefsteiner, Carolin, Sanchez-Duffhues, Gonzalo, Wadsack, Christian

“…The placenta is a unique and pivotal organ in reproduction, controlling crucial growth and cell differentiation processes that ensure a successful pregnancy…”
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Signal transduction of transforming growth factor beta (TGF-β)/Smad3 pathway modulates the functionality of Hofbauer cells (HBC) in preeclampsia by Mercnik, Monika Horvat, Schliefsteiner, Carolin, Wadsack, Christian

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Human placental Hofbauer cells have distinct functional features and omit re-polarization in vitro by Schliefsteiner, Carolin, Horvat-Merčnik, Monika, Kalcher, Christina, Wadsack, Christian

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A paracrine crosstalk between Hofbauer cells (HBCs) and feto-placental endothelial cells (fpECs) contributes to the endothelial to mesenchymal transition (EndoMT) in early onset preeclampsia (EO PE) by Mercnik, Monika Horvat, Schliefsteiner, Carolin, Fluhr, Herbert, Sanchez-Duffhues, Gonzalo, Goumans, Marie-José, Wadsack, Christian

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Fetal-derived HDL regulates placental vascular tone preferentially via endothelial hyperpolarization and not exclusively by eNOS by Schliefsteiner, Carolin, Strahlhofer-Augsten, Manuela, Woelkart, Gerald, Allerkamp, Hanna, Lang-Olip, Ingrid, Wadsack, Christian

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Maternal Gestational Diabetes Mellitus increases placental and foetal lipoprotein-associated Phospholipase A2 which might exert protective functions against oxidative stress by Schliefsteiner, Carolin, Hirschmugl, Birgit, Kopp, Susanne, Curcic, Sanja, Bernhart, Eva Maria, Marsche, Gunther, Lang, Uwe, Desoye, Gernot, Wadsack, Christian

“…Increased Lipoprotein associated phospholipase A 2 (LpPLA 2 ) has been associated with inflammatory pathologies, including Type 2 Diabetes. Studies on LpPLA 2…”
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Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier function and actin organization by Cvitic, Silvija, Strutz, Jasmin, Appel, Hannah M, Weiß, Elisa, Brandl, Waltraud T, Thüringer, Andrea, Bernhart, Eva M, Lassance, Luciana, Wadsack, Christian, Schliefsteiner, Carolin, Sreckovic, Ivana, Kashofer, Karl, Hiden, Ursula

“…Endothelial function and the risk for endothelial dysfunction differ between males and females. Besides the action of estrogen, sex chromosome gene expression…”
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