Search Results - "Schlessinger, Karni"

Wnt signaling pathways meet Rho GTPases by Schlessinger, Karni, Hall, Alan, Tolwinski, Nicholas

“…Wnt ligands and their receptors orchestrate many essential cellular and physiological processes. During development they control differentiation,…”
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Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation by Gough, Daniel J, Corlett, Alicia, Schlessinger, Karni, Wegrzyn, Joanna, Larner, Andrew C, Levy, David E

“…Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor responsive to cytokine signaling and tyrosine kinase…”
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Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity by Schlessinger, Karni, McManus, Edward J, Hall, Alan

“…Scratch-induced disruption of cultured monolayers induces polarity in front row cells that can be visualized by spatially localized polymerization of actin at…”
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Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation by JINBO YANG, CHATTERJEE-KISHORE, Moitreyee, STAUGAITIS, Susan M, NGUYEN, Hannah, SCHLESSINGER, Karni, LEVY, David E, STARK, George R

“…Signal transducer and activator of transcription 3 (STAT3) is phosphorylated on tyrosine residue 705 in response to growth factors or cytokines to form…”
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Essential Role of STAT3 in Postnatal Survival and Growth Revealed by Mice Lacking STAT3 Serine 727 Phosphorylation by Shen, Yuhong, Schlessinger, Karni, Zhu, Xuejun, Meffre, Eric, Quimby, Fred, Levy, David E., Darnell, J. E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells by Xiong, Huizhong, Maraver, Antonio, Latkowski, Jo-Ann, Henderson, Tanya, Schlessinger, Karni, Ding, Yi, Shen, Jie, Tadokoro, Carlos E, Lafaille, Juan J

“…Notch signaling is essential for the development of T cell progenitors through the interaction of NOTCH1 receptor on their surface with the ligand, Delta-like…”
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IL-6 signaling via the STAT3/SOCS3 pathway: Functional Analysis of the Conserved STAT3 N-domain by Zhang, Ling, Badgwell, Donna B, Bevers, Jack J. III, Schlessinger, Karni, Murray, Peter J, Levy, David E, Watowich, Stephanie S

“…The conserved N-domain of the STAT proteins has been implicated in several activities crucial to cytokine signaling including receptor recruitment and STAT…”
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Mitochondrial STAT3 Supports RasDependent Oncogenic Transformation by GOUGH, Daniel J, CORLETT, Alicia, SCHIESSINGER, Karni, WEGRZYN, Joanna, LEARNER, Andrew C, LEVY, David E

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Interactions of the AP-1 Golgi Adaptor with the Polymeric Immunoglobulin Receptor and Their Possible Role in Mediating Brefeldin A-sensitive Basolateral Targeting from the trans-Golgi Network by Orzech, Ena, Schlessinger, Karni, Weiss, Aryeh, Okamoto, Curtis T., Aroeti, Benjamin

“…We provide morphological, biochemical, and functional evidence suggesting that the AP-1 clathrin adaptor complex of the trans-Golgi network interacts with the…”
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Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3 by SCHLESSINGER, Karni, LEVY, David E

“…Signal transducer and activator of transcription 3 (STAT3) has been indirectly implicated in numerous fundamental cellular processes, including proliferation,…”
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APC nuclear membrane association and microtubule polarity by Collin, Ludovic, Schlessinger, Karni, Hall, Alan

“…Background information. Directional cell migration is a fundamental feature of embryonic development, the inflammatory response and the metastatic spread of…”
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Gene expression in WAT from healthy humans and monkeys correlates with FGF21‐induced browning of WAT in mice by Schlessinger, Karni, Li, Wenyu, Tan, Yejun, Liu, Franklin, Souza, Sandra C., Tozzo, Effie, Liu, Kevin, Thompson, John R., Wang, Liangsu, Muise, Eric S.

“…Objective Identify a gene expression signature in white adipose tissue (WAT) that reports on WAT browning and is associated with a healthy phenotype. Methods…”
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Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys by Shang, Jin, Previs, Stephen F, Conarello, Stacey, Chng, Keefe, Zhu, Yonghua, Souza, Sandra C, Staup, Michael, Chen, Ying, Xie, Dan, Zycband, Emanuel, Schlessinger, Karni, Johnson, Victoria Plamadeala, Arreaza, Gladys, Liu, Franklin, Levitan, Diane, Wang, Liangsu, van Heek, Margaret, Erion, Mark, Wang, Yixin, Kelley, David E

“…Insulin resistance and diabetes can develop spontaneously with obesity and aging in rhesus monkeys, highly similar to the natural history of obesity, insulin…”
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Gene expression in WAT from healthy humans and monkeys correlates with FGF 21‐induced browning of WAT in mice by Schlessinger, Karni, Li, Wenyu, Tan, Yejun, Liu, Franklin, Souza, Sandra C., Tozzo, Effie, Liu, Kevin, Thompson, John R., Wang, Liangsu, Muise, Eric S.

“…Objective Identify a gene expression signature in white adipose tissue (WAT) that reports on WAT browning and is associated with a healthy phenotype. Methods…”
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Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice by Bertolotti, Anne, Wang, XiaoZhong, Novoa, Isabel, Jungreis, Rivka, Schlessinger, Karni, Cho, Judy H., West, A. Brian, Ron, David

“…The epithelial cells of the gastrointestinal tract are exposed to toxins and infectious agents that can adversely affect protein folding in the endoplasmic…”
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New and old functions of STAT3: a pivotal target for individualized treatment of cancer by Inghirami, Giorgio, Chiarle, Roberto, Simmons, William J, Piva, Roberto, Schlessinger, Karni, Levy, David E

“…Signal transducers and activators of transcription (STAT) regulate a plethora of cytokine responses. Recently, aberrant signaling by STAT proteins has been…”
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GSK-3β sets Snail's pace by Schlessinger, Karni, Hall, Alan

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GSK-3[beta] sets Snail's pace by Schlessinger, Karni, Hall, Alan

“…Snail, a transcription factor that promotes epithelial-to-mesenchymal transitions during development, has also been implicated in human cancer. A new mechanism…”
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GSK-3beta sets Snail's pace by Schlessinger, Karni, Hall, Alan

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Malignant transformation but not normal cell growth depend on STAT3 by Schlessinger, Karni, Levy, David E.

“…STAT3 has been indirectly implicated in numerous fundamental cellular processes, including proliferation, survival and differentiation. We provide genetic…”
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