Search Results - "Schlapfer, J"

Stereoselective Block of hERG Channel by ( )-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers by Eap, C B, Crettol, S, Rougier, J‐S, Schläpfer, J, Sintra Grilo, L, Déglon, J‐J, Besson, J, Croquette‐Krokar, M, Carrupt, P‐A, Abriel, H

“…Methadone inhibits the cardiac potassium channel hERG and can cause a prolonged QT interval. Methadone is chiral but its therapeutic activity is mainly due to…”
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A whole-genome radiation hybrid panel for bovine gene mapping by Womack, J E, Johnson, J S, Owens, E K, Rexroad, 3rd, C E, Schläpfer, J, Yang, Y P

“…Although the idea of irradiation and fusion gene transfer was published more than 20 years ago and employed in an isolated mapping experiment ten years later,…”
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Late clinical outcome after successful radiofrequency catheter ablation of accessory pathways by Schläpfer, J, Fromer, M

“…Aims To evaluate the long-term clinical results of patients who underwent successful radiofrequency catheter ablation of a symptomatic drug-resistant…”
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radiation hybrid map of bovine chromosome one by Rexroad, C E, Schlapfer, J S, Yang, Y, Harlizius, B, Womack, J E

“…Radiation hybrid (RH) mapping has proven to be an extremely powerful approach to constructing high density maps of human chromosomes and is experiencing…”
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Comparative mapping of bovine chromosome 13 by fluorescence in situ hybridization by Schläpfer, J., Gallagher Jr, D. S., Burzlaff, J. D., Womack, J. E., Stelly, D. M., Taylor, J. F., Davis, S. K.

“…We present chromosomal fluorescence in situ hybridization (FISH) results that both extend the HSA20/BTA13 comparative map as well as cytogenetically anchor two…”
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Brugada syndrome and fever: Genetic and molecular characterization of patients carrying mutations by KELLER, D, ROUGIER, J, KUCERA, J, BENAMMAR, N, FRESSART, V, GUICHENEY, P, MADLE, A, FROMER, M, SCHLAPFER, J, ABRIEL, H

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Brugada syndrome and fever : Genetic and molecular characterization of patients carrying SCN5A mutations by KELLER, Dagmar I, ROUGIER, Jean-Sébastien, KUCERA, Jan P, BENAMMAR, Nawal, FRESSART, Véronique, GUICHENEY, Pascale, MADLE, Alois, FROMER, Martin, SCHLÄPFER, Jürg, ABRIEL, Hugues

“…Brugada syndrome (BrS) is characterized by ventricular tachyarrhythmias leading to sudden cardiac death and is caused, in part, by mutations in the SCN5A gene…”
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Twelve loci from HSA10, HSA11 and HSA20 were comparatively FISH-mapped on river buffalo and sheep chromosomes by Iannuzzi, L, Gallagher, D S, Di Meo, G P, Schlapfer, J, Perucatti, A, Amarante, M R, Incarnato, D, Davis, S K, Taylor, J F, Womack, J E

“…Ten type I loci from HSA10 (IL2RA and VIM), HSA11 (HBB and FSHB) and HSA20 (THBD, AVP/OXT, GNAS1, HCK and TOP1) and two domestic cattle type II loci (CSSM30…”
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Genetic mapping of the prion protein gene (PRNP) on bovine chromosome 13 by Schlapfer, J., Stahlberger-Saitbekova, N., Kuffer, J., Dolf, G.

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P373 Form ?fruste? of long QT syndrome as a possible cause for unexplained syncope revealed by dobutamine infusion by SCHLAPFER, J

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canine linkage map: 39 linkage groups by Lingaas, F, Aarskaug, T, Gerlach, J.A, Juneja, R.K, Fredholm, M, Sampson, J, Suter, N, Holmes, N.G, Binns, M.M, Ryder, E.J

“…A low resolution canine marker map is an important tool in the further advancements in genetic analysis of dog breeds and the control and reduction of the…”
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Canine-Derived Cosmid Probes Containing Microsatellites Can Be Used in Physical Mapping of Arctic Fox (Alopex lagopus) and Chinese Raccoon Dog (Nyctereutes procyonoides procyonoides) Genomes by Rogalska-Niznik, N., Szczerbal, I., Dolf, G., Schläpfer, J., Schelling, C., Switonski, M.

“…Rapid development of the canine marker genome map facilitates genome mapping of other Canidae species. In this study we present chromosomal localization of 18…”
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Genetic relationships in swiss sheep breeds based on microsatellite analysis by Stahlberger-Saitbekova, N, Schlapfer, J, Dolf, G, Gaillard, C

“…Genetic relationships between Swiss sheep breeds were estimated on the basis of microsatellite analysis. In addition to the Swiss breeds wild‐type Mouflon was…”
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new allelic variant in the bovine prion protein gene (PRNP) coding region by Schlapfer, J, Saitbekova, N, Gaillard, C, Dolf, G

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What risk should justify implantable cardioverter defibrillator therapy? by Schläpfer, J, Kappenberger, L, Fromer, M

“…Implantable cardioverter defibrillators (ICDs) were developed to prevent sudden cardiac death in patients with ventricular tachycardia (VT) or ventricular…”
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Development of a cytogenetic map for the Chinese raccoon dog (Nyctereutes procyonoides procyonoides) and the arctic fox (Alopex lagopus) genomes, using canine-derived microsatellite probes by Szczerbal, I, Rogalska-Niznik, N, Schelling, C, Schläpfer, J, Dolf, G, Switonski, M

“…New chromosomal assignments of canine-derived cosmid clones containing microsatellites to the Chinese raccoon dog and arctic fox genomes are presented in the…”
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Acute Hemodynamic Effects of Atrioventricular Pacing at Differing Sites in the Right Ventricle Individually and Simultaneously by BUCKINGHAM, THOMAS A., CANDINAS, RETO, SCHLÄPFER, JÜRG, AEBISCHER, NICOLE, JEANRENAUD, XAVIER, LANDOLT, JACQUELINE, KAPPENBERGER, LUKAS

“…We hypothesized that pacing, which provided a rapid uniform contraction of the ventricles with a narrower QRS, would produce a better stroke volume and cardiac…”
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Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy by Abriel, Hugues, Schläpfer, Jürg, Keller, Dagmar I, Gavillet, Bruno, Buclin, Thierry, Biollaz, Jérôme, Stoller, Rudolf, Kappenberger, Lukas

“…More than 70 drugs present on the Swiss market can cause drug-induced long QT syndrome (LQTS), which is associated with torsades de pointes (TdP) arrhythmias,…”
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Chromosome identification and assignment of DNA clones in the dog using a red fox and dog comparative map by Yang, F, Milne, B.S, Schelling, C, Dolf, G, Schlapfer, J, Switonski, M, Ladon, D, Pienkowska, A, Bosma, A.A, Sargan, D.R

“…We have developed a novel method for identifying dog chromosomes and unambiguously mapping specific clones onto canine chromosomes. This method uses a…”
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Ventricular arrhythmia and torsade de pointe: Dose limiting toxicities of the MDR-modulator S9788 in a phase I trial by Stupp, R., Bauer, J., Pagani, O., Gerard, B., Cerny, T., Sessa, C., Bastian, G., Sarkany, M., Schläpfer, J., Giroux, B., Leyvraz, S.

“…Background: S9788 is a triazineaminopiperidine derivative capable of reversing multidrug resistance (MDR) in vitro. In preclinical models S9788 was several…”
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