Search Results - "Schittek, B"

Lysis of a Broad Range of Epithelial Tumour Cells by Human γδ T Cells: Involvement of NKG2D ligands and T-cell Receptor- versus NKG2D-dependent Recognition by Wrobel, P, Shojaei, H, Schittek, B, Gieseler, F, Wollenberg, B, Kalthoff, H, Kabelitz, D, Wesch, D

“…Human γδ T cells expressing a Vγ9Vδ2 T-cell receptor (TCR) kill various tumour cells including autologous tumours. In addition to TCR-dependent recognition,…”
Get full text

Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment by Meier, F., Busch, S., Lasithiotakis, K., Kulms, D., Garbe, C., Maczey, E., Herlyn, M., Schittek, B.

“…Summary Background  In melanoma, several signalling pathways are constitutively activated. Among them, the RAS/RAF/MEK/ERK (MAPK) and PI3K/AKT (AKT) signalling…”
Get full text

Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge by STEFFEN, H, RIEG, S, WIEDEMANN, I, KALBACHER, H, DEEG, M, SAHL, H.-G, PESCHEL, A, GÖTZ, F, GARBE, C, SCHITTEK, B

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Metastatic pathways and time courses in the orderly progression of cutaneous melanoma by Meier, F., Will, S., Ellwanger, U., Schlagenhauff, B., Schittek, B., Rassner, G., Garbe, C.

“…Summary Background  It is known that two‐thirds of patients who develop clinical metastases following treatment of a primary cutaneous melanoma initially…”
Get full text

Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions by Rieg, S., Garbe, C., Sauer, B., Kalbacher, H., Schittek, B.

“…Summary Background  Antimicrobial peptides (AMPs) are important effector molecules of innate immunity, protecting epithelial surfaces of multicellular…”
Get full text

Resistance to dermcidin-derived peptides is independent of bacterial protease activity by Senyürek, I, Döring, G, Kalbacher, H, Deeg, M, Peschel, A, Wolz, C, Schittek, B

“…Abstract Dermcidin (DCD) is an antimicrobial peptide constitutively expressed in eccrine sweat glands in human skin. By post-secretory proteolytic processing…”
Get full text

Multicentre study on standardisation of melanoma cell culture - an initiative of the German Melanoma Research Network by Eberle, J., Spangler, B., Becker, J. C., Heinemann, S. H., Klein, C. A., Kunz, M., Kuphal, S., Langer, P., Mauch, C., Meierjohann, S., Paschen, A., Schadendorf, D., Schartl, M., Schittek, B., Schönherr, R., Tüting, T., Zigrino, P., Bosserhoff, A. K.

Get full text

Detection of melanoma cells in sentinel lymph nodes, bone marrow and peripheral blood by a reverse transcription-polymerase chain reaction assay in patients with primary cutaneous melanoma: association with Breslow's tumour thickness by Blaheta, H-J., Paul, T., Sotlar, K., Maczey, E., Schittek, B., Paul, A., Moehrle, M., Breuninger, H., Bueltmann, B., Rassner, G., Garbe, C.

“…Background Tyrosinase reverse transcription–polymerase chain reaction (RT–PCR) has been shown to be highly sensitive in detecting tumour cells in melanoma…”
Get full text

Specifically regulated genes in malignant melanoma tissues identified by subtractive hybridization by HIPFEL, R, SCHITTEK, B, BODINGBAUER, Y, GARBE, C

“…A polymerase chain reaction (PCR)-based subtractive hybridization technique was used to identify transformation-related genes in malignant melanoma. Melanoma…”
Get full text

Interlaboratory Evaluation of a New Reverse Transcriptase Polymerase Chain Reaction–Based Enzyme-Linked Immunosorbent Assay for the Detection of Circulating Melanoma Cells: A Multicenter Study of the Dermatologic Cooperative Oncology Group by REINHOLD, U, BERKIN, C, SCHITTEK, B, SEITER, S, UGUREL, S, VOLKENANDT, M, TILGEN, W, BOSSERHOFF, A.-K, DEUTSCHMANN, A, GARBE, C, GLÄSER, R, HEIN, R, KRÄHN, G, PETER, R. U, RAPPL, G

“…Reverse transcription-polymerase chain reaction (RT-PCR)-based detection of tyrosinase mRNA is the most frequently used laboratory method for the detection of…”
Get full text

Natural occurrence and origin of somatically mutated memory B cells in mice by SCHITTEK, B, RAJEWSKY, K

“…While most murine peripheral B cells express germline-encoded antibodies of classes M and D (mu+ delta+ cells), small numbers of memory B cells expressing…”
Get full text

Morphoea is neither associated with features of Borrelia burgdorferi infection, nor is this agent detectable in lesional skin by polymerase chain reaction by Weide, B., Schittek, B., Klyscz, T., Schüz, K., Stark, M., Rassner, G., Wilske, B., Garbe, C.

“…Background The aetiology of morphoea is still unknown. Borrelia burgdorferi as a causative agent of morphoea has been discussed since 1985, but the…”
Get full text

Lysis of a broad range of epithelial tumour cells by human gamma delta T cells: involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition by Wrobel, P, Shojaei, H, Schittek, B, Gieseler, F, Wollenberg, B, Kalthoff, H, Kabelitz, D, Wesch, D

“…Human gammadelta T cells expressing a V gamma 9V delta 2 T-cell receptor (TCR) kill various tumour cells including autologous tumours. In addition to…”
Get full text

Significance of serum protein S100 levels in screening for melanoma metastasis: does protein S100 enable early detection of melanoma recurrence? by Schlagenhauff, B, Schittek, B, Ellwanger, U, Stroebel, W, Blum, A, Schwarz, M, Rassner, G, Garbe, C

“…A number of recent reports suggest serum protein S100 as a prognostic parameter in patients with metastatic melanoma. In the present study, serum protein S100…”
Get full text

294 Dermcidin: a new player in a familiar case of Hidradenitis Suppurativa by Tricarico, P.M., Gratton, R., Del Vecchio, C., Ura, B., Sommella, E., Chersi, K., Krismer, B., Schittek, B., Boniotto, M., Crovella, S.

Get full text

Additional reverse transcription-polymerase chain reaction of peripheral slices is not superior to analysis of the central slice in sentinel lymph nodes from melanoma patients by Blaheta, H-J., Roeger, S., Sotlar, K., Schittek, B., Breuninger, H., Bueltmann, B., Garbe, C.

“…Summary Background  The status of the sentinel lymph node (SLN) is an important prognostic factor in patients with cutaneous melanoma. Reverse…”
Get full text

Detection of micrometastasis in sentinel lymph nodes of patients with primary cutaneous melanoma by Blaheta, H J, Schittek, B, Breuninger, H, Garbe, C

“…The technique of sentinel lymph node (SLN) biopsy has been demonstrated to be highly predictive for the detection of melanoma micrometastases in the regional…”
Get more information

Polymerase chain reaction in the detection of circulating tumour cells in peripheral blood of melanoma patients by Schittek, B, Blaheta, H J, Ellwanger, U, Garbe, C

“…Conflicting results were obtained by various research groups using the tyrosinase reverse transcription polymerase chain reaction (RT-PCR) for detecting…”
Get more information

Deficiency of Dermcidin-Derived Antimicrobial Peptides in Sweat of Patients with Atopic Dermatitis Correlates with an Impaired Innate Defense of Human Skin In Vivo by Rieg, Siegbert, Steffen, Heiko, Seeber, Silke, Humeny, Andreas, Kalbacher, Hubert, Dietz, Klaus, Garbe, Claus, Schittek, Birgit

“…Antimicrobial peptides are an integral part of the epithelial innate defense system. Dermcidin (DCD) is a recently discovered antimicrobial peptide with a…”
Get full text

567 Ultraviolet (UV)-A irradiation induces changes in metabolism which influence, via enhanced Warburg effect, melanoma invasion by Kamenisch, Y., Baban, T., Ivanova, I., Schuller, W., Metzler, G., Bauer, J., Garbe, C., Schittek, B., Röcken, M., Berneburg, M.

Get full text