Search Results - "Schirosi, Laura"
-
1
Intratumoral, rather than stromal, CD8+ T cells could be a potential negative prognostic marker in invasive breast cancer patients
Published in Translational oncology (01-03-2019)“…BACKGROUND: Tumor infiltrating lymphocytes (TILs) are widely considered a key sign of the immune interaction between host and tumor, and potentially prognostic…”
Get full text
Journal Article -
2
Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients?
Published in BMC cancer (18-11-2016)“…In clinical practice the gold standard method to assess BRAF status in patients with metastatic melanoma is based on molecular assays. Recently, a…”
Get full text
Journal Article -
3
De-Implementation of Axillary Staging and Radiotherapy in Low-Risk Breast Cancer Patients Aged 70-79 Years from Six Italian Cancer Institutes
Published in Current oncology (Toronto) (01-04-2023)“…In women aged ≥70 with low-risk breast cancer (BrC), some major international guidelines recommend against sentinel lymph node biopsy (for example, those from…”
Get full text
Journal Article -
4
Downstream Signaling of Inflammasome Pathway Affects Patients' Outcome in the Context of Distinct Molecular Breast Cancer Subtypes
Published in Pharmaceuticals (Basel, Switzerland) (24-05-2022)“…Inflammasomes are protein complexes involved in the regulation of different biological conditions. Over the past few years, the role of NLRP3 in different…”
Get full text
Journal Article -
5
Discordance between FISH, IHC, and NGS Analysis of ALK Status in Advanced Non–Small Cell Lung Cancer (NSCLC): a Brief Report of 7 Cases
Published in Translational oncology (01-02-2019)“…BACKGROUND: Anaplastic lymphoma kinase (ALK) rearrangement represents a landmark in the targeted therapy of non–small cell lung cancer (NSCLC)…”
Get full text
Journal Article -
6
Role of Chemotherapy and the Receptor Tyrosine Kinases KIT, PDGFRα, PDGFRβ, and Met in Large-Cell Neuroendocrine Carcinoma of the Lung
Published in Journal of clinical oncology (01-12-2005)“…Purpose Pulmonary large-cell neuroendocrine carcinoma (LCNEC) is a relatively uncommon, high-grade neuroendocrine tumor sharing several features with…”
Get full text
Journal Article -
7
Tumor Infiltrating Lymphocytes and NHERF1 Impact on Prognosis of Breast Cancer Patients
Published in Translational oncology (01-02-2020)“…BACKGROUND: Breast cancer (BC) is a heterogeneous disease, and patients with apparently similar clinicopathological characteristics in clinical practice show…”
Get full text
Journal Article -
8
VEGFA Status as a Predictive Marker of Therapy Outcome in Metastatic Gastric Cancer Patients Following Ramucirumab-Based Treatment
Published in Biomedicines (07-10-2023)“…Metastatic gastric cancer (mGC) often has a poor prognosis and may benefit from a few targeted therapies. Ramucirumab-based anti-angiogenic therapy targeting…”
Get full text
Journal Article -
9
The role of fetal autopsy and placental examination in the causes of fetal death: a retrospective study of 132 cases of stillbirths
Published in Archives of gynecology and obstetrics (01-02-2011)“…Purpose To investigate the most plausible cause of stillbirth by evaluating clinical records and postmortem examination findings including placental analysis…”
Get full text
Journal Article -
10
Thyroglobulin Determination in Fine Needle Aspiration Biopsy Washout of Suspicious Lymph Nodes in Thyroid Carcinoma Follow up
Published in Endocrine, metabolic & immune disorders drug targets (01-01-2017)“…Differentiated thyroid carcinomas (DTCs) account for about 1% of all human malignancies. Cervical lymph nodes metastases and recurrences in the thyroid bed…”
Get more information
Journal Article -
11
Imatinib inhibits in vitro proliferation of cells derived from a pleural solitary fibrous tumor expressing platelet-derived growth factor receptor-beta
Published in Lung cancer (Amsterdam, Netherlands) (01-05-2009)“…Abstract We examined the in vitro effects of imatinib (Novartis Pharma AG, Basel, Switzerland) as a possible inhibitor of PDGFR pathway on cells derived from a…”
Get full text
Journal Article -
12
VEGF and TWIST1 in a 16‐biomarker immunoprofile useful for prognosis of breast cancer patients
Published in International journal of cancer (01-11-2017)“…This study concerns the expression of biomarkers involved in diverse pathways, such as progression, DNA repair mechanisms and angiogenesis to establish an…”
Get full text
Journal Article -
13
NHERF1 together with PARP1 and BRCA1 expression as a new potential biomarker to stratify breast cancer patients
Published in Oncotarget (12-09-2017)“…It has been recognized that Na /H Exchanger Regulatory Factor 1 (NHERF1) in breast cancer (BC) acts as a tumor suppressor or as an oncogenic protein, depending…”
Get full text
Journal Article -
14
Impressive response with imatinib in a heavily pretreated patient with metastatic c-KIT mutated thymic carcinoma
Published in Journal of clinical oncology (20-11-2011)Get full text
Journal Article -
15
The role of rapid on site evaluation on touch imprint cytology and brushing during conventional bronchoscopy
Published in Diagnostic cytopathology (01-07-2021)“…Background The increase in immunohistochemical and molecular predictive tests in lung cancer requires new strategies for managing small samples taken during…”
Get full text
Journal Article -
16
Pleuro-pulmonary Solitary Fibrous Tumors : A Clinicopathologic, Immunohistochemical, and Molecular Study of 88 Cases Confirming the Prognostic Value of de Perrot Staging System and p53 Expression, and Evaluating the Role of c-kit, BRAF, PDGFRs (α/β), c-met, and EGFR
Published in The American journal of surgical pathology (01-11-2008)“…Pleuro-pulmonary solitary fibrous tumor (SFT) is a relatively uncommon mesenchymal neoplasm of uncertain histogenesis, unknown molecular features, and…”
Get full text
Journal Article -
17
Fine Needle Aspiration Cytology: A Tool to Study NHERF1 Expression as a Potential Marker of Aggressiveness in Lung Cancer
Published in Molecular biotechnology (01-06-2015)“…Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide and cytology is often the only diagnostic approach. Na + /H + exchanger…”
Get full text
Journal Article -
18
β-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients
Published in Oncotarget (18-10-2016)“…There is an increasing need to identify new biomarkers in colorectal cancer (CRC) to further characterize this malignancy. β-catenin plays a central role in…”
Get full text
Journal Article -
19
Immunoprofile from tissue microarrays to stratify familial breast cancer patients
Published in Oncotarget (29-09-2015)“…Familial breast cancer (BC) is a heterogeneous disease with variable prognosis. The identification of an immunoprofile is important to predict tumor behavior…”
Get full text
Journal Article -
20
Intratumoral, rather than stromal, CD8+ T cells could be a potential negative prognostic marker in invasive breast cancer patients12
Published in Translational oncology (22-01-2019)“…BACKGROUND: Tumor infiltrating lymphocytes (TILs) are widely considered a key sign of the immune interaction between host and tumor, and potentially prognostic…”
Get full text
Journal Article