Search Results - "Schirizzi, Annalisa"

Autotaxin-Lysophosphatidate Axis: Promoter of Cancer Development and Possible Therapeutic Implications by Laface, Carmelo, Ricci, Angela Dalia, Vallarelli, Simona, Ostuni, Carmela, Rizzo, Alessandro, Ambrogio, Francesca, Centonze, Matteo, Schirizzi, Annalisa, De Leonardis, Giampiero, D'Alessandro, Rosalba, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Autotaxin (ATX) is a member of the ectonucleotide pyrophosphate/phosphodiesterase ( ) family; it is encoded by the gene. ATX is a secreted glycoprotein and…”
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Corrigendum: Variations in circulating levels of angiopoietin-2 over time are predictive of ramucirumab-paclitaxel therapy outcome in advanced gastric cancer: results of prospective study by D'Alessandro, Rosalba, Refolo, Maria Grazia, Schirizzi, Annalisa, De Leonardis, Giampiero, Donghia, Rossella, Guerra, Vito, Giannelli, Gianluigi, Lolli, Ivan Roberto, Laterza, Maria Maddalena, De Vita, Ferdinando, Messa, Caterina, Lotesoriere, Claudio

“…[This corrects the article DOI: 10.3389/fonc.2022.862116.]…”
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Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab-Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study by D'Alessandro, Rosalba, Refolo, Maria Grazia, Schirizzi, Annalisa, De Leonardis, Giampiero, Donghia, Rossella, Guerra, Vito, Giannelli, Gianluigi, Lolli, Ivan Roberto, Laterza, Maria Maddalena, De Vita, Ferdinando, Messa, Caterina, Lotesoriere, Claudio

“…The combination of paclitaxel and ramucirumab is the second-line therapy of choice in the treatment of advanced gastric cancer. To date, no biomarkers are…”
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The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines by Schirizzi, Annalisa, Contino, Marialessandra, Carrieri, Livianna, Riganti, Chiara, De Leonardis, Giampiero, Scavo, Maria Principia, Perrone, Maria Grazia, Miciaccia, Morena, Kopecka, Joanna, Refolo, Maria Grazia, Lotesoriere, Claudio, Depalo, Nicoletta, Rizzi, Federica, Giannelli, Gianluigi, Messa, Caterina, D'Alessandro, Rosalba

“…Paclitaxel (PTX) interferes with microtubule architecture by binding to β-tubulin, thereby blocking progression at the G2/M phase and inducing apoptosis. This…”
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VEGFA Status as a Predictive Marker of Therapy Outcome in Metastatic Gastric Cancer Patients Following Ramucirumab-Based Treatment by Schirizzi, Annalisa, Arshadi, Aram, Tolomeo, Doron, Schirosi, Laura, Valentini, Anna Maria, De Leonardis, Giampiero, Refolo, Maria Grazia, Donghia, Rossella, Storlazzi, Clelia Tiziana, Zito, Alfredo, Ricci, Angela Dalia, Vallarelli, Simona, Ostuni, Carmela, Bencivenga, Maria, De Manzoni, Giovanni, Messa, Caterina, Armentano, Raffaele, Giannelli, Gianluigi, Lotesoriere, Claudio, D'Alessandro, Rosalba

“…Metastatic gastric cancer (mGC) often has a poor prognosis and may benefit from a few targeted therapies. Ramucirumab-based anti-angiogenic therapy targeting…”
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Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models by Francavilla, Fabio, Sarcina, Federica, Schepetkin, Igor A., Kirpotina, Lilya N., Contino, Marialessandra, Schirizzi, Annalisa, De Leonardis, Giampiero, Khlebnikov, Andrei I., D'Alessandro, Rosalba, Quinn, Mark T., Lacivita, Enza, Leopoldo, Marcello

“…Formyl peptide receptor-1 (FPR1) is a G protein-coupled chemoattractant receptor that plays a crucial role in the trafficking of leukocytes into the sites of…”
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High levels of autotaxin and lysophosphatidic acid predict poor outcome in treatment of resectable gastric carcinoma by Schirizzi, Annalisa, Donghia, Rossella, De Nunzio, Valentina, Renna, Natasha, Centonze, Matteo, De Leonardis, Giampiero, Lorusso, Vincenza, Fantasia, Alessia, Coletta, Sergio, Stabile, Dolores, Ferro, Annalisa, Notarnicola, Maria, Ricci, Angela D., Lotesoriere, Claudio, Lahn, Michael, D’Alessandro, Rosalba, Giannelli, Gianluigi

“…Although early-stage gastric cancer is a candidate for curative surgical resection, the absence of specific early symptoms results in a late diagnosis and…”
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Tumor Immune Microenvironment in Intrahepatic Cholangiocarcinoma: Regulatory Mechanisms, Functions, and Therapeutic Implications by Ricci, Angela Dalia, Rizzo, Alessandro, Schirizzi, Annalisa, D'Alessandro, Rosalba, Frega, Giorgio, Brandi, Giovanni, Shahini, Endrit, Cozzolongo, Raffaele, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Treatment options for intrahepatic cholangiocarcinoma (iCCA), a highly malignant tumor with poor prognosis, are limited. Recent developments in immunotherapy…”
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Durvalumab in advanced cholangiocarcinoma: is someone knocking down the door? by Ricci, Angela Dalia, D'Alessandro, Rosalba, Rizzo, Alessandro, Schirizzi, Annalisa, Vallarelli, Simona, Ostuni, Carmela, Troiani, Laura, Lolli, Ivan Roberto, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Following the practice-changing results observed in several hematological and solid tumors, immunotherapy with immune checkpoint inhibitors (ICIs) has been…”
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Insights into the molecular pathogenesis of cardiospondylocarpofacial syndrome: MAP3K7 c.737-7A > G variant alters the TGFβ-mediated α-SMA cytoskeleton assembly and autophagy by Micale, Lucia, Morlino, Silvia, Biagini, Tommaso, Carbone, Annalucia, Fusco, Carmela, Ritelli, Marco, Giambra, Vincenzo, Zoppi, Nicoletta, Nardella, Grazia, Notarangelo, Angelantonio, Schirizzi, Annalisa, Mazzoccoli, Gianluigi, Grammatico, Paola, Wade, Emma M., Mazza, Tommaso, Colombi, Marina, Castori, Marco

“…Transforming growth factor beta-activated kinase 1 (TAK1) is a highly conserved kinase protein encoded by MAP3K7, and activated by multiple extracellular…”
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Targeting Angiogenesis in the Era of Biliary Tract Cancer Immunotherapy: Biological Rationale, Clinical Implications, and Future Research Avenues by Schirizzi, Annalisa, De Leonardis, Giampiero, Lorusso, Vincenza, Donghia, Rossella, Rizzo, Alessandro, Vallarelli, Simona, Ostuni, Carmela, Troiani, Laura, Lolli, Ivan Roberto, Giannelli, Gianluigi, Ricci, Angela Dalia, D'Alessandro, Rosalba, Lotesoriere, Claudio

“…Although biliary tract cancers are traditionally considered rare in Western countries, their incidence and mortality rates are rising worldwide. A better…”
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Loss-of-function variants in exon 4 of TAB2 cause a recognizable multisystem disorder with cardiovascular, facial, cutaneous, and musculoskeletal involvement by Micale, Lucia, Morlino, Silvia, Carbone, Annalucia, Carissimo, Annamaria, Nardella, Grazia, Fusco, Carmela, Palumbo, Orazio, Schirizzi, Annalisa, Russo, Federica, Mazzoccoli, Gianluigi, Breckpot, Jeroen, De Luca, Chiara, Ferraris, Alessandro, Giunta, Cecilia, Grammatico, Paola, Haanpää, Maria K., Mancano, Giorgia, Forzano, Giulia, Cacchiarelli, Davide, Van Esch, Hilde, Callewaert, Bert, Rohrbach, Marianne, Castori, Marco

“…This study aimed to describe a multisystemic disorder featuring cardiovascular, facial, musculoskeletal, and cutaneous anomalies caused by heterozygous…”
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Exon-Trapping Assay Improves Clinical Interpretation of COL11A1 and COL11A2 Intronic Variants in Stickler Syndrome Type 2 and Otospondylomegaepiphyseal Dysplasia by Micale, Lucia, Morlino, Silvia, Schirizzi, Annalisa, Agolini, Emanuele, Nardella, Grazia, Fusco, Carmela, Castellana, Stefano, Guarnieri, Vito, Villa, Roberta, Bedeschi, Maria Francesca, Grammatico, Paola, Novelli, Antonio, Castori, Marco

“…Stickler syndrome (SS) is a hereditary connective tissue disorder affecting bones, eyes, and hearing. Type 2 SS and the SS variant otospondylomegaepiphyseal…”
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