Search Results - "Schinner, S"

Wnt-signalling and the metabolic syndrome by Schinner, S

“…The Wnt-signalling pathway plays a well-established role in embryogenesis and tumourigenesis. However, recent data puts Wnt-signalling in the context of…”
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Wingless-type MMTV integration site family (WNT) signalling in pancreatic beta cells—more complex than expected by Schinner, S

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Evidence for an exercise induced increase of TNF-[alpha] and IL-6 in marathon runners by Bernecker, C, Scherr, J, Schinner, S, Braun, S, Scherbaum, W. A, Halle, M

“…Regular physical activity of moderate intensity improves cardiovascular risk factors including low-grade inflammation. However, acute vigorous exercise such as…”
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Evidence for an exercise induced increase of TNF-α and IL-6 in marathon runners by Bernecker, C., Scherr, J., Schinner, S., Braun, S., Scherbaum, W. A., Halle, M.

“…Regular physical activity of moderate intensity improves cardiovascular risk factors including low‐grade inflammation. However, acute vigorous exercise such as…”
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Molecular mechanisms of insulin resistance by Schinner, S., Scherbaum, W. A., Bornstein, S. R., Barthel, A.

“…Currently, we observe an epidemic expansion of diabetes mellitus. In subjects with Type 2 diabetes the resistance of fat, muscle and liver to insulin is the…”
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Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis by Christodoulides, C, Laudes, M, Cawthorn, W.P, Schinner, S, Soos, M, O'Rahilly, S, Sethi, J.K, Vidal-Puig, A

“…Secretion of Wnts by adipose cells has an important role in the control of murine adipogenesis. We present the first evidence that a Wnt antagonist, Dickkopf 1…”
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Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules by Schinner, S, Ülgen, F, Papewalis, C, Schott, M, Woelk, A, Vidal-Puig, A, Scherbaum, W. A

“…Aims/hypothesis Adipocytes secrete signalling molecules that elicit responses from target cells, including pancreatic beta cells. Wnt signalling molecules have…”
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Subclinical hypothyroidism and the prevalence of the metabolic syndrome by Liu, C, Scherbaum, W A, Schott, M, Schinner, S

“…There is currently controversial data regarding the prevalence of MS among SCH patients. The aim of the study was to investigate the prevalence of MS in an…”
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Adipocyte-derived products induce the transcription of the StAR promoter and stimulate aldosterone and cortisol secretion from adrenocortical cells through the Wnt-signaling pathway by Schinner, S, Willenberg, H.S, Krause, D, Schott, M, Lamounier-Zepter, V, Krug, A.W, Ehrhart-Bornstein, M, Bornstein, S.R, Scherbaum, W.A

“…Context: Obesity is associated with hypersecretion of cortisol and aldosterone and a high prevalence of arterial hypertension. At the cellular level, a direct…”
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New mechanisms to control aldosterone synthesis by Willenberg, H S, Schinner, S, Ansurudeen, I

“…Arterial hypertension is a frequent and leading cardiovascular risk factor, and primary aldosteronism is a well-recognized cause of secondary hypertension…”
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Human adipocytes induce an ERK1/2 MAP kinases-mediated upregulation of steroidogenic acute regulatory protein (StAR) and an angiotensin II -- sensitization in human adrenocortical cells by Krug, A.W, Vleugels, K, Schinner, S, Lamounier-Zepter, V, Ziegler, C.G, Bornstein, S.R, Ehrhart-Bornstein, M

“…Objectives: Hypertension is a major complication of overweight with frequently elevated aldosterone levels in obese patients. Our previous work suggests a…”
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In vitro and mouse in vivo characterization of the potent free fatty acid 1 receptor agonist TUG-469 by Urban, C., Hamacher, A., Partke, H. J., Roden, M., Schinner, S., Christiansen, E., Due-Hansen, M. E., Ulven, T., Gohlke, H., Kassack, M. U.

“…Activation of the G protein-coupled free fatty acid receptor 1 (FFA1; formerly known as GPR40) leads to an enhancement of glucose-stimulated insulin secretion…”
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ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocytokine-mediated aldosterone secretion by Vleugels, K, Schinner, S, Krause, D, Morawietz, H, Bornstein, S R, Ehrhart-Bornstein, M, Krug, A W

“…Obesity is one major risk factor for the development of arterial hypertension, and the development of obesity-related hypertension has been associated with…”
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Role of the novel mTOR inhibitor RAD001 (everolimus) in anaplastic thyroid cancer by Papewalis, C, Wuttke, M, Schinner, S, Willenberg, H S, Baran, A M, Scherbaum, W A, Schott, M

“…Activation of the phosphatidylinositol-3-kinase (PI3K) signaling cascade is increasingly recognized as a common feature of thyroid follicular neoplasms. Among…”
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HLA-A2 phenotype may be protective against Graves' disease but not against Hashimoto's thyroiditis in Caucasians by Bernecker, C, Ostapczuk, M, Vordenbäumen, S, Ehlers, M, Thiel, A, Schinner, S, Willenberg, H, Scherbaum, W A, Schott, M

“…Graves' disease (GD) and Hashimoto's thyroiditis (HT) are the most common autoimmune thyroid diseases (AITDs) affecting up to 5% of the general population. In…”
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Inhibition of human insulin gene transcription by peroxisome proliferator‐activated receptor γ and thiazolidinedione oral antidiabetic drugs by Schinner, S, Krätzner, R, Baun, D, Dickel, C, Blume, R, Oetjen, E

“…Background and purpose:  The transcription factor peroxisome proliferator‐activated receptor γ (PPARγ) is essential for glucose homeostasis. PPARγ ligands…”
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A new mutation in the menin gene causes the multiple endocrine neoplasia type 1 syndrome with adrenocortical carcinoma by Haase, M., Anlauf, M., Schott, M., Schinner, S., Kaminsky, E., Scherbaum, W. A., Willenberg, Holger S.

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant tumor syndrome that may be caused by mutations in the MEN1 gene on 11q13. Loss of function…”
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Intensive glycemic control lowers plasma visfatin levels in patients with type 2 diabetes by Zhu, J, Schott, M, Liu, R, Liu, C, Shen, B, Wang, Q, Mao, X, Xu, K, Wu, X, Schinner, S, Papewalis, C, Scherbaum, W A

“…Visfatin is an independent association factor for type 2 diabetes mellitus (T2DM). In order to evaluate the plasma visfatin levels and investigate whether…”
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Reproducibility of Elecsys anti-TSHR test results in a lot-to-lot comparison by Hermsen, D, Eckstein, A, Schinner, S, Willenberg, H S, Thiel, A, Scherbaum, W A, Schott, M

“…Most recently, a new rapid and fully-automated TSH receptor autoantibody (TRAb) assay has been established. This assay system uses the M22 human monoclonal…”
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The effects of the endothelium on adrenal steroidogenesis and growth are mainly mediated by proteins other than endothelin-1 by Paramonova, I, Haase, M, Mülders-Opgenoorth, B, Ansurudeen-Rafi, I, Bornstein, S R, Papewalis, C, Schinner, S, Schott, M, Scherbaum, W A, Willenberg, H S

“…The endothelium releases factors stimulating the adrenal cortex. It is also known that endothelin-1 (ET-1) promotes generation of cortisol and aldosterone, and…”
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