Search Results - "Schinella, R"
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Activation of AMPK by Medicinal Plants and Natural Products: Its Role in Type 2 Diabetes Mellitus
Published in Mini reviews in medicinal chemistry (01-01-2019)“…Type-2 Diabetes (T2D) is a metabolic disease characterized by permanent hyperglycemia, whose development can be prevented or delayed by using therapeutic…”
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Phenolics as GABAA Receptor Ligands: An Updated Review
Published in Molecules (Basel, Switzerland) (08-03-2022)“…Natural products can act as potential GABA modulators, avoiding the undesirable effects of traditional pharmacology used for the inhibition of the central…”
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Anti-Inflammatory and Antioxidant Chinese Herbal Medicines: Links between Traditional Characters and the Skin Lipoperoxidation "Western" Model
Published in Antioxidants (23-03-2022)“…The relationship between lipid peroxidation and inflammation has been accepted as a paradigm in the field of topical inflammation. The underlying biochemical…”
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Modulation of Cox‐1, 5‐, 12‐ and 15‐Lox by Popular Herbal Remedies Used in Southern Italy Against Psoriasis and Other Skin Diseases
Published in Phytotherapy research (01-01-2015)“…Acanthus mollis (Acanthaceae), Achillea ligustica, Artemisia arborescens and Inula viscosa (Asteraceae) are used in Southern Italy against psoriasis and other…”
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Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused heart
Published in American journal of physiology. Heart and circulatory physiology (01-09-2016)“…Previous results from our laboratory showed that phosphorylation of ryanodine receptor 2 (RyR2) by Ca(2+) calmodulin-dependent kinase II (CaMKII) was a…”
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Human apolipoprotein A-I natural variants: molecular mechanisms underlying amyloidogenic propensity
Published in PloS one (28-08-2012)“…Human apolipoprotein A-I (apoA-I)-derived amyloidosis can present with either wild-type (Wt) protein deposits in atherosclerotic plaques or as a hereditary…”
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Dietary Supplementation with Yerba Mate ( Ilex paraguariensis ) Infusion Increases IRS-1 and PI3K mRNA Levels and Enhances Insulin Sensitivity and Secretion in Rat Pancreatic Islets
Published in Plants (Basel) (01-07-2023)“…"Yerba mate" (YM), an aqueous extract of Ilex paraguariensis, has antioxidant, diuretic, cardio-protective and hypoglycaemic properties. Since its effect on…”
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Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis
Published in PloS one (19-07-2011)“…Amyloidoses constitute a group of diseases in which soluble proteins aggregate and deposit extracellularly in tissues. Nonhereditary apolipoprotein A-I…”
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Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action
Published in Journal of applied physiology (1985) (01-12-2008)“…Centro de Investigaciones Cardiovasculares, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Buenos Aires, Argentina Submitted 6 May…”
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Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside
Published in European journal of pharmacology (07-02-2003)“…Three flavonoids, gnaphaliin, pinocembrin and tiliroside, isolated from Helichrysum italicum, were studied in vitro for their antioxidant and/or scavenger…”
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Natural Products for the Treatment of Type 2 Diabetes Mellitus
Published in Planta medica (01-08-2015)“…Type 2 diabetes mellitus is a metabolic disease characterized by persistent hyperglycemia. High blood sugar can produce long-term complications such as…”
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In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy
Published in Pflügers Archiv (01-11-2011)“…Growing in vitro evidence suggests NHE-1, a known target for reactive oxygen species (ROS), as a key mediator in cardiac hypertrophy (CH). Moreover, NHE-1…”
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Antioxidant activity of anti-inflammatory plant extracts
Published in Life sciences (1973) (18-01-2002)“…The antioxidant properties of twenty medical herbs used in the traditional Mediterranean and Chinese medicine were studied. Extracts from Forsythia suspensa,…”
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Anti-inflammatory Effects of South American Tanacetum vulgare
Published in Journal of pharmacy and pharmacology (01-09-1998)“…In recent years the role of phenolic compounds and sesquiterpene lactones, particularly parthenolide, in the anti‐migraine and anti‐inflammatory effects of…”
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Phenolics as GABA A Receptor Ligands: An Updated Review
Published in Molecules (Basel, Switzerland) (08-03-2022)“…Natural products can act as potential GABA modulators, avoiding the undesirable effects of traditional pharmacology used for the inhibition of the central…”
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Acute treatment with copoazú fermented extract ameliorates myocardial ischemia-reperfusion injury via eNOS activation
Published in Journal of functional foods (01-07-2017)“…•Copoazú fermented extract (CFE) protects against ischemia-reperfusion injury.•Fermentation decreases the antioxidant power and increases the cardioprotective…”
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Double-blind, randomized study of primary hormonal treatment of stage D2 prostate carcinoma: flutamide versus diethylstilbestrol
Published in Journal of clinical oncology (01-08-1996)“…Patients with stage D2 prostate carcinoma are often treated initially with hormones to decrease endogenous testosterone. Therapy with diethylstilbestrol (DES),…”
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Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet
Published in Journal of ethnopharmacology (30-01-2020)“…Cocoa extracts rich in polyphenols are used as potential agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important hallmarks of…”
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A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum
Published in European journal of pharmacology (24-01-2003)“…Six acetophenones ( 1– 6) and one γ-pyrone ( 7), previously isolated from Helichrysum italicum, were tested for their ability to inhibit enzymatic and…”
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