Search Results - "Schindlbeck, Katharina A."
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Network imaging biomarkers: insights and clinical applications in Parkinson's disease
Published in Lancet neurology (01-07-2018)“…Parkinson's disease presents several practical challenges: it can be difficult to distinguish from atypical parkinsonian syndromes, clinical ratings can be…”
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Functional brain networks in the evaluation of patients with neurodegenerative disorders
Published in Nature reviews. Neurology (01-02-2023)“…Network analytical tools are increasingly being applied to brain imaging maps of resting metabolic activity (PET) or blood oxygenation-dependent signals…”
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Serotonergic pathology and Braak's staging hypothesis in Parkinson's disease
Published in Lancet neurology (01-08-2019)“…The gene encoding for α-synuclein (SNCA) was the first to be linked to familial Parkinson's disease.1 At the same time, α-synuclein was identified as the main…”
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Publisher Correction: Functional brain networks in the evaluation of patients with neurodegenerative disorders
Published in Nature reviews. Neurology (01-06-2023)Get full text
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Cognition-Related Functional Topographies in Parkinson’s Disease: Localized Loss of the Ventral Default Mode Network
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2021)“…Abstract Cognitive dysfunction in Parkinson’s disease (PD) is associated with increased expression of the PD cognition-related pattern (PDCP), which overlaps…”
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Disordered network structure and function in dystonia: pathological connectivity vs. adaptive responses
Published in Cerebral cortex (New York, N.Y. 1991) (24-05-2023)“…Abstract Primary dystonia is thought to emerge through abnormal functional relationships between basal ganglia and cerebellar motor circuits. These…”
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LRRK2 and GBA Variants Exert Distinct Influences on Parkinson’s Disease-Specific Metabolic Networks
Published in Cerebral cortex (New York, N.Y. 1991) (14-05-2020)“…Abstract The natural history of idiopathic Parkinson’s disease (PD) varies considerably across patients. While PD is generally sporadic, there are known…”
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Stereotyped Relationship Between Motor and Cognitive Metabolic Networks in Parkinson's Disease
Published in Movement disorders (01-11-2022)“…ABSTRACT Background Idiopathic Parkinson's disease (iPD) is associated with two distinct brain networks, PD‐related pattern (PDRP) and PD‐related cognitive…”
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Adaptive and pathological connectivity responses in Parkinson's disease brain networks
Published in Cerebral cortex (New York, N.Y. 1991) (07-02-2023)“…Functional imaging has been used extensively to identify and validate disease-specific networks as biomarkers in neurodegenerative disorders. It is not known,…”
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Diplopia in Parkinson's disease: Indication of a cortical phenotype with cognitive dysfunction?
Published in Acta neurologica Scandinavica (01-10-2021)“…Background Visual disturbances are increasingly recognized as common non‐motor symptoms in Parkinson's disease (PD). In PD patients, intermittent diplopia has…”
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Metabolic Network Abnormalities in Drug‐Naïve Parkinson's Disease
Published in Movement disorders (01-04-2020)“…Background An ideal imaging biomarker for a neurodegenerative disorder should be able to measure abnormalities in the earliest stages of the disease. Objective…”
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Spot Sign in Acute Intracerebral Hemorrhage in Dynamic T1-Weighted Magnetic Resonance Imaging
Published in Stroke (1970) (01-02-2016)“…BACKGROUND AND PURPOSE—In computed tomographic imaging of acute intracerebral hemorrhage spot sign on computed tomographic angiography has been established as…”
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Neuropathological correlation supports automated image-based differential diagnosis in parkinsonism
Published in European journal of nuclear medicine and molecular imaging (01-10-2021)“…Purpose Up to 25% of patients diagnosed as idiopathic Parkinson’s disease (IPD) have an atypical parkinsonian syndrome (APS). We had previously validated an…”
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Characterization of diplopia in non-demented patients with Parkinson's disease
Published in Parkinsonism & related disorders (01-12-2017)“…Although diplopia is considered a frequent symptom of Parkinson's disease (PD), little is known about its clinical manifestation, associated mechanisms and…”
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Response to Letter Regarding Article, “Spot Sign in Acute Intracerebral Hemorrhage in Dynamic T1-Weighted Magnetic Resonance Imaging”
Published in Stroke (1970) (01-05-2016)Get full text
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The single intake of levodopa modulates implicit learning in drug naïve, de novo patients with idiopathic Parkinson’s disease
Published in Journal of Neural Transmission (01-06-2016)“…Although dopamine is known to aggravate implicit learning, the exact impact on behaviour when feedback is unavailable remains unclear. Previous studies…”
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Necessity of long‐term alertness in levodopa‐carbidopa intestinal gel infusion for PD patients
Published in Movement disorders (01-02-2017)Get full text
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Restless legs syndrome is a relevant comorbidity in patients with inflammatory bowel disease
Published in International journal of colorectal disease (01-07-2018)“…Background and aims In patients with inflammatory bowel disease (IBD), restless legs syndrome (RLS) may occur as an extraintestinal disease manifestation. Iron…”
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Somatosensory symptoms in unmedicated de novo patients with idiopathic Parkinson’s disease
Published in Journal of Neural Transmission (01-03-2016)“…Parkinson’s disease (PD) is a neurodegenerative condition presenting with motor and non-motor symptoms including somatosensory disturbances. As neuropathic…”
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Parkinson's disease-related pattern (PDRP) identified using resting-state functional MRI: Validation study
Published in Neuroimage. Reports (01-09-2021)“…Spatial covariance mapping of brain activity has been used increasingly with metabolic imaging to detect and quantify abnormal disease patterns in patient…”
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