Search Results - "Schiltz, Louis R"
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DNA binding triggers tetramerization of the glucocorticoid receptor in live cells
Published in Proceedings of the National Academy of Sciences - PNAS (19-07-2016)“…Transcription factors dynamically bind to chromatin and are essential for the regulation of genes. Although a large percentage of these proteins appear to…”
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Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding
Published in Molecular cell (08-07-2011)“…Ligand-dependent transcription by the nuclear receptor glucocorticoid receptor (GR) is mediated by interactions with coregulators. The role of these…”
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3
Single-molecule analysis of steroid receptor and cofactor action in living cells
Published in Nature communications (21-06-2017)“…Population-based assays have been employed extensively to investigate the interactions of transcription factors (TFs) with chromatin and are often interpreted…”
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4
Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism
Published in Cell (19-08-2011)“…The glucocorticoid receptor (GR), like other eukaryotic transcription factors, regulates gene expression by interacting with chromatinized DNA response…”
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5
Novel biosensor for high-throughput detection of progesterone receptor-interacting endocrine disruptors
Published in Scientific reports (06-03-2024)“…Progesterone receptor (PR)-interacting compounds in the environment are associated with serious health hazards. However, methods for their detection in…”
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Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor
Published in PLoS biology (01-03-2014)“…Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses…”
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Reprogramming the Chromatin Landscape: Interplay of the Estrogen and Glucocorticoid Receptors at the Genomic Level
Published in Cancer research (Chicago, Ill.) (15-08-2013)“…Cross-talk between estrogen receptors (ER) and glucocorticoid receptors (GR) has been shown to contribute to the development and progression of breast cancer…”
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The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities
Published in Nucleic acids research (09-12-2022)“…The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that controls metabolic and homeostatic processes essential for life…”
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The RNA Helicases p68/p72 and the Noncoding RNA SRA Are Coregulators of MyoD and Skeletal Muscle Differentiation
Published in Developmental cell (01-10-2006)“…MyoD regulates skeletal myogenesis. Since proteins associated with MyoD exert regulatory functions, their identification is expected to contribute important…”
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Prevalent Glucocorticoid and Androgen Activity in US Water Sources
Published in Scientific reports (06-12-2012)“…Contamination of the environment with endocrine disrupting chemicals (EDCs) is a major health concern. The presence of estrogenic compounds in water and their…”
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11
HDAC1 Acetylation Is Linked to Progressive Modulation of Steroid Receptor-Induced Gene Transcription
Published in Molecular cell (09-06-2006)“…Although histone deacetylases (HDACs) are generally viewed as corepressors, we show that HDAC1 serves as a coactivator for the glucocorticoid receptor (GR)…”
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Dynamic access of the glucocorticoid receptor to response elements in chromatin
Published in The international journal of biochemistry & cell biology (01-01-2009)“…Transcriptional activation as a rate-limiting step of gene expression is often triggered by an environmental stimulus that is transmitted through a signaling…”
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13
Are Assumptions about the Model Type Necessary in Reaction-Diffusion Modeling? A FRAP Application
Published in Biophysical journal (02-03-2011)“…At present, fluorescence recovery after photobleaching (FRAP) data are interpreted using various types of reaction-diffusion (RD) models: the model type is…”
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14
Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity
Published in Journal of cell science (01-02-2009)“…Gene regulation often appears deterministic in the average cell population, but transcription is a probabilistic process at the single-cell level. Although…”
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Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility
Published in Molecular cell (19-09-2019)“…Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the mechanisms regulating this process are unclear. Although many…”
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Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions
Published in Nature structural & molecular biology (01-01-2014)“…ATP-dependent chromatin remodeling is essential for the dynamic organization of chromatin structure. Genome-wide localization and activity analyses now suggest…”
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Chromatin dynamics and the evolution of alternate promoter states
Published in Chromosome research (01-02-2006)“…Eucaryotic gene transcriptional switches utilize changes both in the activity and composition of soluble transcription factor complexes, and epigenetic…”
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18
Tax Relieves Transcriptional Repression by Promoting Histone Deacetylase 1 Release from the Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat
Published in Journal of Virology (01-07-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genome-Wide Identification of Basic Helix–Loop–Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus
Published in Endocrinology (Philadelphia) (01-05-2017)“…Glucocorticoids regulate hippocampal function in part by modulating gene expression through the glucocorticoid receptor (GR). GR binding is highly cell type…”
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Acetylation of Nucleosomal Histones by p300 Facilitates Transcription from Tax-Responsive Human T-Cell Leukemia Virus Type 1 Chromatin Template
Published in Molecular and Cellular Biology (01-07-2002)“…AUTHOR'S CORRECTION ( vol. 22 , p. 6930 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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