Search Results - "Schillinger, Jasmin"

Rational correction of pathogenic conformational defects in HTRA1 by Beaufort, Nathalie, Ingendahl, Linda, Merdanovic, Melisa, Schmidt, Andree, Podlesainski, David, Richter, Tim, Neumann, Thorben, Kuszner, Michael, Vetter, Ingrid R., Stege, Patricia, Burston, Steven G., Filipovic, Anto, Ruiz-Blanco, Yasser B., Bravo-Rodriguez, Kenny, Mieres-Perez, Joel, Beuck, Christine, Uebel, Stephan, Zobawa, Monika, Schillinger, Jasmin, Malik, Rainer, Todorov-Völgyi, Katalin, Rey, Juliana, Roberti, Annabell, Hagemeier, Birte, Wefers, Benedikt, Müller, Stephan A., Wurst, Wolfgang, Sanchez-Garcia, Elsa, Zimmermann, Alexander, Hu, Xiao-Yu, Clausen, Tim, Huber, Robert, Lichtenthaler, Stefan F., Schmuck, Carsten, Giese, Michael, Kaiser, Markus, Ehrmann, Michael, Dichgans, Martin

“…Loss-of-function mutations in the homotrimeric serine protease HTRA1 cause cerebral vasculopathy. Here, we establish independent approaches to achieve the…”
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Targeted Protein Unfolding at the Golgi Apparatus by Schillinger, Jasmin, Hellerschmied, Doris

“…Maintaining protein homeostasis (proteostasis) is vital to cellular and organismal health. How the Golgi apparatus, the central protein maturation and sorting…”
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HTRA1-Dependent Cell Cycle Proteomics by Schillinger, Jasmin, Severin, Katharina, Kaschani, Farnusch, Kaiser, Markus, Ehrmann, Michael

“…The HTRA1 gene encoding an evolutionary conserved protein quality-control factor can be epigenetically silenced or inactivated by mutation under pathologic…”
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High resolution analysis of proteolytic substrate processing by Schillinger, Jasmin, Koci, Michelle, Bravo-Rodriguez, Kenny, Heilmann, Geronimo, Kaschani, Farnusch, Kaiser, Markus, Beuck, Christine, Luecke, Hartmut, Huber, Robert, Hellerschmied, Doris, Burston, Steven G., Ehrmann, Michael

“…Members of the widely conserved high temperature requirement A (HtrA) family of serine proteases are involved in multiple aspects of protein quality control…”
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Identification of the Natural Product Rotihibin A as a TOR Kinase Signaling Inhibitor by Unbiased Transcriptional Profiling by Halder, Vivek, Oeljeklaus, Julian, Heilmann, Geronimo, Krahn, Jan H., Liu, Yanlin, Xiong, Yan, Schlicht, Markus, Schillinger, Jasmin, Kracher, Barbara, Ehrmann, Michael, Kombrink, Erich, Kaschani, Farnusch, Kaiser, Markus

“…Bioactive natural products are important starting points for developing chemical tools for biological research. For elucidating their bioactivity profile,…”
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Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action by Bongard, Jens, Schmitz, Anna Laura, Wolf, Alex, Zischinsky, Gunther, Pieren, Michel, Schellhorn, Birgit, Bravo‐Rodriguez, Kenny, Schillinger, Jasmin, Koch, Uwe, Nussbaumer, Peter, Klebl, Bert, Steinmann, Jörg, Buer, Jan, Sanchez‐Garcia, Elsa, Ehrmann, Michael, Kaiser, Markus

“…Despite the availability of hundreds of antibiotic drugs, infectious diseases continue to remain one of the most notorious health issues. In addition, the…”
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