Search Results - "Schilling, William H.K."

The relationship between viral clearance rates and disease progression in early symptomatic COVID-19: a systematic review and meta-regression analysis by Singh, Shivani, Boyd, Simon, Schilling, William H K, Watson, James A, Mukaka, Mavuto, White, Nicholas J

“…Effective antiviral drugs accelerate viral clearance in acute COVID-19 infections; the relationship between accelerating viral clearance and reducing severe…”
Get full text

Does hydroxychloroquine still have any role in the COVID-19 pandemic? by Schilling, William Hk, White, Nicholas J

“…: The 4-aminoquinolines, chloroquine, and hydroxychloroquine have been used for over 70 years for malaria and rheumatological conditions, respectively. Their…”
Get more information

No evidence that chloroquine or hydroxychloroquine induce hemolysis in G6PD deficiency by Schilling, William H.K., Bancone, Germana, White, Nicholas J.

Get full text

Reflections on Participation in a Trial on Hydroxychloroquine as Prevention for COVID-19 among Health Workers in Niger by Kabore, Youssouf, Vatrinet, Renaud, Guindo, Ousmane, Moussa, Souleymane H, Schilling, William H K, Grais, Rebecca F

“…In 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a rapidly emerging virus causing the coronavirus disease 2019 (COVID-19) pandemic, had…”
Get full text

Blood culture negative endocarditis in the modern era of 16S rRNA sequencing by Godfrey, Rebecca, Curtis, Sally, Schilling, William HK, James, P Rachael

“…Blood culture negative endocarditis (BCNE) accounts for up to 20% of infective endocarditis. While the most common cause of BCNE remains the initiation of…”
Get full text

Antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19 (PLATCOV): an open-label, phase 2, randomised, controlled, adaptive trial by Schilling, William H K, Jittamala, Podjanee, Watson, James A, Boyd, Simon, Luvira, Viravarn, Siripoon, Tanaya, Ngamprasertchai, Thundon, Batty, Elizabeth M, Cruz, Cintia, Callery, James J, Singh, Shivani, Saroj, Manisaree, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tanglakmankhong, Nuttakan, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Madmanee, Wanassanan, Kouhathong, Jindarat, Suwannasin, Kanokon, Pagornrat, Watcharee, Piaraksa, Nattaporn, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Poovorawan, Kittiyod, Potaporn, Manus, Srisubat, Attasit, Loharjun, Bootsakorn, Taylor, Walter R J, Chotivanich, Vasin, Chotivanich, Kesinee, Imwong, Mallika, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J, White, Nicholas J, Schilling, William HK, Phumratanaprapin, Weerapong, Luvira, Viravarn, Callery, James J, Day, Nicholas PJ, Pukrittayakamee, Sasithon, Boyd, Simon, Cruz, Cintia, Dondorp, Arjen M, Taylor, Walter RJ, Watson, James A, Piyaphanee, Watcharapong, Poovorawan, Kittiyod, Ngamprasertchai, Thundon, Siripoon, Tanaya, Hanboonkunupakarn, Borimas, Chotivanich, Kesinee, Jittamala, Podjanee, Imwong, Mallika, Thaipadungpanit, Janjira, Ekkapongpisit, Maneerat, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Batty, Elizabeth M, Singh, Shivani, Chotivanich, Vasin, Ruksakul, Wiroj, Sangketchon, Chunlanee, Hanboonkunupakarn, Pongtorn, Sookprome, Sakol, Teixeira, Mauro, Almeida, Pedro J, Aguiar, Renato S, Santos, Franciele, Ashley, Elizabeth, Vongsouvath, Manivanh, Phommasone, Koukeo, Dubot-Pérès, Audrey, Vidhamaly, Sisouphanh, Chingsanoon, Ammala, Bisayher, Sixiong, Chommanam, Danoy, Evans, Terry John, Vidhamaly, Vayouly, Boutthasavong, Latsaniphone, Mayxay, Mayfong, Potaporn, Manus, Srisubat, Attasit, Loharjun, Bootsakorn

“…Molnupiravir and ritonavir-boosted nirmatrelvir are the two leading oral COVID-19 antiviral treatments, but their antiviral activities in patients have not…”
Get full text

Clinical Antiviral Efficacy of Remdesivir in Coronavirus Disease 2019: An Open-Label, Randomized Controlled Adaptive Platform Trial (PLATCOV) by Jittamala, Podjanee, Schilling, William H K, Watson, James A, Luvira, Viravarn, Siripoon, Tanaya, Ngamprasertchai, Thundon, Almeida, Pedro J, Ekkapongpisit, Maneerat, Cruz, Cintia, Callery, James J, Boyd, Simon, Anunsittichai, Orawan, Hongsuwan, Maliwan, Singhaboot, Yutatirat, Pagornrat, Watcharee, Tuntipaiboontana, Runch, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Keayarsa, Srisuda, Madmanee, Wanassanan, Aguiar, Renato S, Santos, Franciele M, Batty, Elizabeth M, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Sookprome, Sakol, Poovorawan, Kittiyod, Imwong, Mallika, Taylor, Walter R J, Chotivanich, Vasin, Sangketchon, Chunlanee, Ruksakul, Wiroj, Chotivanich, Kesinee, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J

“…Abstract Background Uncertainty over the therapeutic benefit of parenteral remdesivir in coronavirus disease 2019 (COVID-19) has resulted in varying treatment…”
Get full text

Temporal changes in SARS-CoV-2 clearance kinetics and the optimal design of antiviral pharmacodynamic studies: an individual patient data meta-analysis of a randomised, controlled, adaptive platform study (PLATCOV) by Wongnak, Phrutsamon, Schilling, William H K, Jittamala, Podjanee, Boyd, Simon, Luvira, Viravarn, Siripoon, Tanaya, Ngamprasertchai, Thundon, Batty, Elizabeth M, Singh, Shivani, Kouhathong, Jindarat, Pagornrat, Watcharee, Khanthagan, Patpannee, Hanboonkunupakarn, Borimas, Poovorawan, Kittiyod, Mayxay, Mayfong, Chotivanich, Kesinee, Imwong, Mallika, Pukrittayakamee, Sasithon, Ashley, Elizabeth A, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J, Watson, James A, Callery, James, Cruz, Cintia, Taylor, Walter, Thaipadungpanit, Janjira, Ekkapongpisit, Maneerat, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad, Keayarsa, Srisuda, Anunsittichai, Orawan, Hongsuwan, Maliwan, Singhaboot, Yutatirat, Madmanee, Wanassanan, Tuntipaiboontana, Runch, Promsongsil, Amornrat, Saroj, Manisaree, Suwannasin, Kanokon, Beer, Ellen, Asawasriworanan, Tanatchakorn, Blacksell, Stuart, Panapipat, Salwaluk, Waithira, Naomi, Tarning, Joel, Tanglakmankhong, Nuttakan, Almeida, Pedro J, Aguiar, Renato S, Ascencao, Fernando, Esper, Lisia, Vongsouvath, Manivanh, Phommasone, Koukeo, Dubot-Pérès, Audrey, Vidhamaly, Sisouphanh, Chingsanoon, Ammala, Bisayher, Sixiong, Chommanam, Danoy, Evans, Terry, Vidhamaly, Vayouly, Boutthasavong, Latsaniphone, Vongphachanh, Susath, Potaporn, Manus, Srisubat, Attasit, Loharjun, Bootsakorn, Beg, M Asim, Kazi, Abdul Momin, Qamar, Farah, Ghanchi, Najia, Mahmood, Syed Faisal, Hanboonkunupakarn, Pongtorn, Sookprome, Sakol, Chotivanich, Vasin, Ruksakul, Wiroj, Sangketchon, Chunlanee

“…Effective antiviral drugs prevent hospitalisation and death from COVID-19. Antiviral efficacy can be efficiently assessed in vivo by measuring rates of…”
Get full text

Clinical antiviral efficacy of favipiravir in early COVID-19 (PLATCOV): an open-label, randomised, controlled, adaptive platform trial by Luvira, Viravarn, Schilling, William H K, Jittamala, Podjanee, Watson, James A, Boyd, Simon, Siripoon, Tanaya, Ngamprasertchai, Thundon, Almeida, Pedro J, Ekkapongpisit, Maneerat, Cruz, Cintia, Callery, James J, Singh, Shivani, Tuntipaiboontana, Runch, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Keayarsa, Srisuda, Madmanee, Wanassanan, Aguiar, Renato S, Santos, Franciele M, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Poovorawan, Kittiyod, Imwong, Mallika, Taylor, Walter R J, Chotivanich, Vasin, Chotivanich, Kesinee, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J

“…In early symptomatic COVID-19 treatment, high dose oral favipiravir did not accelerate viral clearance. Favipiravir, an anti-influenza drug, has in vitro…”
Get full text

Pharmacometrics of high-dose ivermectin in early COVID-19 from an open label, randomized, controlled adaptive platform trial (PLATCOV) by Schilling, William H K, Jittamala, Podjanee, Watson, James A, Ekkapongpisit, Maneerat, Siripoon, Tanaya, Ngamprasertchai, Thundon, Luvira, Viravarn, Pongwilai, Sasithorn, Cruz, Cintia, Callery, James J, Boyd, Simon, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Piaraksa, Nattaporn, Suwannasin, Kanokon, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Sookprome, Sakol, Poovorawan, Kittiyod, Thaipadungpanit, Janjira, Blacksell, Stuart, Imwong, Mallika, Tarning, Joel, Taylor, Walter R J, Chotivanich, Vasin, Sangketchon, Chunlanee, Ruksakul, Wiroj, Chotivanich, Kesinee, Teixeira, Mauro Martins, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J

“…There is no generally accepted methodology for in vivo assessment of antiviral activity in SARS-CoV-2 infections. Ivermectin has been recommended widely as a…”
Get full text

Cutaneous stigmata associated with insulin resistance and increased cardiovascular risk by Schilling, William H. K., Crook, Martin A.

“…Certain cutaneous conditions have been reported to be associated with diabetes mellitus, insulin resistance, and metabolic syndrome. In this novel review…”
Get full text

The WHO guideline on drugs to prevent COVID-19: small numbers- big conclusions by Schilling, William HK, Callery, James J., Chandna, Arjun, Hamers, Raph L, Watson, James A, White, Nicholas J

“…The World Health Organization living guideline on drugs to prevent COVID-19 has recently advised that ongoing trials evaluating hydroxychloroquine in…”
Get full text

Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project by Chandna, Arjun, Chew, Rusheng, Shwe Nwe Htun, Nan, Peto, Thomas J, Zhang, Meiwen, Liverani, Marco, Brummaier, Tobias, Phommasone, Koukeo, Perrone, Carlo, Pyae Phyo, Aung, Sattabongkot, Jetsumon, Roobsoong, Wanlapa, Nguitragool, Wang, Sen, Aninda, Ibna Zaman, Sazid, Sandar Zaw, Aye, Batty, Elizabeth, Waithira, Naomi, Abdad, Mohammad Yazid, Blacksell, Stuart D, Bodhidatta, Ladaporn, Callery, James J, Fagnark, Watcharintorn, Huangsuranun, Witchayoot, Islam, Shayla, Lertcharoenchoke, Sanchai, Lohavittayavikant, Salisa, Mukaka, Mavuto, Moul, Vanna, Kumer Neogi, Amit, Nedsuwan, Supalert, Pongvongsa, Tiengkham, Ponsap, Pimsiri, Richard-Greenblatt, Melissa, Schilling, William H K, Thaipadungpanit, Janjira, Tripura, Rupam, Dondorp, Arjen M, Mayxay, Mayfong, White, Nicholas J, Nosten, François, Smithuis, Frank, Ashley, Elizabeth A, Maude, Richard J, Day, Nicholas P J, Lubell, Yoel

“…In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health…”
Get full text

Chloroquine/ hydroxychloroquine prevention of coronavirus disease (COVID-19) in the healthcare setting; protocol for a randomised, placebo-controlled prophylaxis study (COPCOV) by Schilling, William H.K., Callery, James J., Taylor, Walter, Mukaka, Mavuto, Ekkapongpisit, Maneerat, Watson, James A, Chandna, Arjun, Panapipat, Salwaluk, Tubprasert, Jaruwan, Yuentrakul, Prayoon, Waithira, Naomi, Cope, Tanya, Dhorda, Mehul, Cruz, Cintia, von Seidlein, Lorenz, Milton, Joanne, LLewelyn, Martin, Adler, Amanda, Chotivanich, Kesinee, Cheah, Phaik Yeong, Ashley, Elizabeth A., Mayxay, Mayfong, Dondorp, Arjen M., Phumratanaprapin, Weerapong, Day, Nicholas P.J., White, Nicholas

“…There is no proven preventative therapy or vaccine against COVID-19. Theinfection has spread rapidly and there has already been a substantial adverse impact on…”
Get full text

Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project by Chandna, Arjun, Chew, Rusheng, Shwe Nwe Htun, Nan, Peto, Thomas J., Zhang, Meiwen, Liverani, Marco, Brummaier, Tobias, Phommasone, Koukeo, Perrone, Carlo, Pyae Phyo, Aung, Sattabongkot, Jetsumon, Roobsoong, Wanlapa, Nguitragool, Wang, Sen, Aninda, Ibna Zaman, Sazid, Sandar Zaw, Aye, Batty, Elizabeth, Waithira, Naomi, Abdad, Mohammad Yazid, Blacksell, Stuart D., Bodhidatta, Ladaporn, Callery, James J., Fagnark, Watcharintorn, Huangsuranun, Witchayoot, Islam, Shayla, Lertcharoenchoke, Sanchai, Lohavittayavikant, Salisa, Mukaka, Mavuto, Moul, Vanna, Kumer Neogi, Amit, Nedsuwan, Supalert, Pongvongsa, Tiengkham, Ponsap, Pimsiri, Richard-Greenblatt, Melissa, Schilling, William H.K., Thaipadungpanit, Janjira, Tripura, Rupam, Dondorp, Arjen M., Mayxay, Mayfong, White, Nicholas J., Nosten, François, Smithuis, Frank, Ashley, Elizabeth A., Maude, Richard J., Day, Nicholas P.J., Lubell, Yoel

“…In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health…”
Get full text