Search Results - "Schiller, J T"

Papillomavirus L1 Major Capsid Protein Self-Assembles into Virus-Like Particles that are Highly Immunogenic by Kirnbauer, R., Booy, F., Cheng, N., Lowy, D. R., Schiller, J. T.

“…Infection by certain human papillomavirus types is regarded as the major risk factor in the development of cervical cancer, one of the most common cancers of…”
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Safety and Immunogenicity Trial in Adult Volunteers of a Human Papillomavirus 16 L1 Virus-Like Particle Vaccine by Harro, Clayton D., Pang, Yuk-Ying Susana, Roden, Richard B. S., Hildesheim, Allan, Wang, Zhaohui, Reynolds, Mary Jane, Mast, T. Christopher, Robinson, Robin, Murphy, Brian R., Karron, Ruth A., Dillner, Joakim, Schiller, John T., Lowy, Douglas R.

“…Background: Studies in animal models have shown that systemic immunization with a papillomavirus virus-like particle (VLP) vaccine composed of L1, a major…”
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Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles by KIRNBAUER, R, TAUB, J, GREENSTONE, H, RODEN, R, DÜRST, M, GISSMANN, L, LOWY, D. R, SCHILLER, J. T

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Papillomavirus-Like Particles Induce Acute Activation of Dendritic Cells by Lenz, Petra, Day, Patricia M, Pang, Yuk-Ying S, Frye, Stephan A, Jensen, Peter N, Lowy, Douglas R, Schiller, John T

“…The role of viral structural proteins in the initiation of adaptive immune responses is poorly understood. To address this issue, we focused on the effect of…”
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Specific Antibody Levels at the Cervix During the Menstrual Cycle of Women Vaccinated With Human Papillomavirus 16 Virus–Like Particles by Nardelli-Haefliger, Denise, Wirthner, Daniel, Schiller, John T., Lowy, Douglas R., Hildesheim, Allan, Ponci, Françoise, De Grandi, Pierre

“…Background: In early-phase trials, a human papillomavirus 16 (HPV16) virus–like particle (VLP) vaccine has been shown to be well tolerated, immunogenic, and…”
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Human papillomavirus type 16 virus-like particles expressed in attenuated Salmonella typhimurium elicit mucosal and systemic neutralizing antibodies in mice by NARDELLI-HAEFLIGER, D, RODEN, R. B. S, BENYACOUB, J, SAHLI, R, KRAEHENBUHL, J.-P, SCHILLER, J. T, LACHAT, P, POTTS, A, DE GRANDI, P

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Efficacy of a Carrageenan gel Against Transmission of Cervical HPV (CATCH): interim analysis of a randomized, double-blind, placebo-controlled, phase 2B trial by Magnan, S., Tota, J.E., El-Zein, M., Burchell, A.N., Schiller, J.T., Ferenczy, A., Tellier, P.-P., Coutlée, F., Franco, E.L., Rodrigues, A., Morykon, N., Rodrigues, R., Bouten, S., Shapiro, S., Guénoun, J., Slavetchva, N.

“…To evaluate the efficacy of a carrageenan-based lubricant gel in reducing the risk of genital human papillomavirus (HPV) infections in women. We conducted a…”
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Serologically diagnosed infection with human papillomavirus type 16 and risk for subsequent development of cervical carcinoma: nested case-control study by Lehtinen, Matti, Dillner, Joakim, Knekt, Paul, Luostarinen, Tapio, Aromaa, Arpo, Kirnbauer, Reinhard, Koskela, Pentti, Paavonen, Jorma, Peto, Richard, Schiller, John T, Hakama, Matti

“…Abstract Objective: To study human papillomavirus type 16 in the aetiology of cervical carcinoma. Design: Within a cohort of 18814 Finnish women followed for…”
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Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope by Roden, R B, Armstrong, A, Haderer, P, Christensen, N D, Hubbert, N L, Lowy, D R, Schiller, J T, Kirnbauer, R

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Seropositivities to Human Papillomavirus Types 16, 18, or 33 Capsids and to Chlamydia trachomatis Are Markers of Sexual Behavior by Dillner, Joakim, Kallings, Ingegerd, Brihmer, Christina, Sikström, Bo, Koskela, Pentti, Lehtinen, Matti, Schiller, John T., Sapp, Martin, Mårdh, Per Anders

“…The association of seropositivity to human papillomavirus (HPV) capsids of types 11, 16, 18, or 33 with sexual behavior was investigated. Among 1002 women…”
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Prospective Seroepidemiologic Study of Human Papillomavirus Infection as a Risk Factor for Invasive Cervical Cancer by Dillner, Joakim, Lehtinen, Matti, Björge, Tone, Luostarinen, Tapio, Youngman, Linda, Koskela, Pentti, Hallmans, Göran, Paavonen, Jorma, Sapp, Martin, Schiller, John T, Hakulinen, Timo, Thoresen, Steinar, Hakama, Matti, Jellum, Egil, Gislefoss, Randi Elin

“…Background: Major risk factors for invasive cervical cancer include infection with human papillomavirus (HPV), infection with other sexually transmitted…”
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In vitro generation and type-specific neutralization of a human papillomavirus type 16 virion pseudotype by Roden, R B, Greenstone, H L, Kirnbauer, R, Booy, F P, Jessie, J, Lowy, D R, Schiller, J T

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Genital Human Papillomavirus Infection by Lowy, Douglas R., Kirnbauer, Reinhard, Schiller, John T.

“…Genital human papillomavirus (HPV) infection is a common sexually transmitted disease that at the present time is not effectively controlled or treated. Many…”
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HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes by Hawley‐Nelson, P., Vousden, K.H., Hubbert, N.L., Lowy, D.R., Schiller, J.T.

“…The human papillomavirus types (HPVs) most often associated with cancer of the cervix, such as HPV16, have been reported previously to immortalize normal human…”
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New Associations of Human Papillomavirus, Simian Virus 40, and Epstein-Barr Virus with Human Cancer by Wong, May, Pagano, Joseph S., Schiller, John T., Tevethia, Satvir S., Raab-Traub, Nancy, Gruber, Jack

“…In cancers with a strong EBV association, EBV DNA and proteins are detected in all tumor cells (3). The EBV genome is clonal (i.e., developed from a single EBV…”
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Seroreactivity to Human Papillomavirus Types 16, 18, 31, and 45 Virus-Like Particles in a Case-Control Study of Cervical Squamous Intraepithelial Lesions by Wideroff, L., Schiffman, M., Haderer, P., Armstrong, A., Greer, C. E., Manos, M. M., Burk, R. D., Scott, D. R., Sherman, M. E., Schiller, J. T., Hoover, R. N., Tarone, R. E., Kirnbauer, R.

“…Serum IgG antibodies to human papillomavirus (HPV) types 16, 18, 31, and 45 virus-like particles were measured in a nested case-control study of cervical…”
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A virus-like particle enzyme-linked immunosorbent assay detects serum antibodies in a majority of women infected with human papillomavirus type 16 by Kirnbauer, R, Hubbert, N L, Wheeler, C M, Becker, T M, Lowy, D R, Schiller, J T

“…Previous studies have demonstrated that genital infection with high-risk types of human papillomavirus (HPV), most often HPV16, is the most significant risk…”
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Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice by Domingos-Pereira, S, Decrausaz, L, Derré, L, Bobst, M, Romero, P, Schiller, J T, Jichlinski, P, Nardelli-Haefliger, D

“…Human papillomaviruses (HPV)-related cervical cancer is the second leading cause of cancer death in women worldwide. Despite active development, HPV E6/E7…”
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Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes by HUBBERT, N. L, SEDMAN, S. A, SCHILLER, J. T

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The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture by SEDMAN, S. A, BARBOSA, M. S, VASS, W. C, HUBBERT, N. L, HAAS, J. A, LOWY, D. R, SCHILLER, J. T

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