Search Results - "Schildkraut, Joseph J."

Toward a Rapidly Acting Antidepressant: The Normetanephrine and Extraneuronal Monoamine Transporter (Uptake 2) Hypothesis by Schildkraut, Joseph J., Mooney, John J.

“…OBJECTIVE: The authors considered the possible role of the extraneuronal monoamine transporter (uptake 2) in accounting for the delay in clinical action of…”
Get full text

Increased Gsα within blood cell membrane lipid microdomains in some depressive disorders: An exploratory study by Mooney, John J, Samson, Jacqueline A, McHale, Nancy L, Pappalarado, Kathleen M, Alpert, Jonathan E, Schildkraut, Joseph J

“…Abstract The stimulatory guanine nucleotide binding protein Gs couples many cellular receptors to adenylate cyclase, and the Gsα subunit activates all 9…”
Get full text

Enhanced norepinephrine output during long-term desipramine treatment: A possible role for the extraneuronal monoamine transporter (SLC22A3) by Mooney, John J, Samson, Jacqueline A, Hennen, John, Pappalardo, Kathleen, McHale, Nancy, Alpert, Jonathan, Koutsos, Martha, Schildkraut, Joseph J

“…Abstract To study the delay (2–6 weeks) between initial administration of norepinephrine reuptake inhibitor antidepressants and onset of clinical…”
Get full text

Antipsychotic medication, prolactin elevation, and ovarian function in women with schizophrenia and schizoaffective disorder by Canuso, Carla M., Goldstein, Jill M., Wojcik, Joanne, Dawson, Ree, Brandman, Danielle, Klibanski, Anne, Schildkraut, Joseph J., Green, Alan I.

“…Some, but not all, antipsychotics elevate serum prolactin. Antipsychotic-induced hyperprolactinemia is thought to account for high rates of menstrual…”
Get full text

Then Melancholy, Now Depression: A Modern Interpretation of Rembrandtʼs Mental State in Midlife by Schildkraut, Joseph J, Cohn, Marjorie B, Hawkins, Harold

“…The authors identify two Rembrandt etchings of 1642, Saint Jerome in a Dark Chamber and A Scholar at a Table by Candlelight, as self-portraits. Considered with…”
Get full text

Saint Jerome in a Dark Chamber: Rembrandt's Metaphoric Portrayal of the Depressed Mind by Schildkraut, Joseph J.

“…Schildkraut discusses Rembrandt's Saint Jerome in a Dark Chamber painting, which portrays the mystery of the depressed mind. The painting was Rembrandt's…”
Get full text

Clozapine reduces alcohol drinking in Syrian golden hamsters by Green, Alan I., Chau, David T., Keung, Wing Ming, Dawson, Ree, Mesholam, Raquelle I., Schildkraut, Joseph J.

“…Alcohol abuse contributes substantially to the overall morbidity of schizophrenia. While typical antipsychotic medications do not limit alcohol use in patients…”
Get full text

Mind and mood in modern art, II: Depressive disorders, spirituality, and early deaths in the abstract expressionist artists of the New York School by Schildkraut, J J, Hirshfeld, A J, Murphy, J M

“…This article documents the high prevalence of mood disorders in a group of 15 of the mid-twentieth-century Abstract Expressionist artists of the New York…”
Get more information

Hypothalamic–pituitary–adrenal axis effects on plasma homovanillic acid in man by Posener, Joel A, Schatzberg, Alan F, Williams, Gordon H, Samson, Jacqueline A, McHale, Nancy L, Bessette, Meghan P, Schildkraut, Joseph J

“…Background: Effects of the hypothalamic–pituitary–adrenal (HPA) axis on central dopaminergic systems have been proposed to underlie the development of…”
Get full text

Signal Transduction by Platelet Adenylate Cyclase: Alterations in Depressed Patients May Reflect Impairment in the Coordinated Integration of Cellular Signals (Coincidence Detection) by Mooney, John J, Samson, Jacqueline A, McHale, Nancy L, Colodzin, Robin, Alpert, Jonathan, Koutsos, Martha, Schildkraut, Joseph J

“…Background: Adenylate cyclase (AC) responds to distinct but coincident signals from the agonist-stimulated G-protein G s and the inhibitory G-protein G i by…”
Get full text

Norepinephrine Turnover and Metabolism in Rat Brain after Long-Term Administration of Imipramine by Schildkraut, Joseph J., Winokur, Andrew, Applegate, Clarence W.

“…The rate of disappearance of intracisternally administered tritiated norepinephrine from rat brain is decreased after a single dose of the tricyclic…”
Get full text

Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action by Schildkraut, J J, Schanberg, S M, Breese, G R, Kopin, I J

Get more information

Increased Gs[alpha] within blood cell membrane lipid microdomains in some depressive disorders: An exploratory study by Mooney, John J, Samson, Jacqueline A, McHale, Nancy L, Pappalarado, Kathleen M, Alpert, Jonathan E, Schildkraut, Joseph J

“…The stimulatory guanine nucleotide binding protein Gs couples many cellular receptors to adenylate cyclase, and the Gs[alpha] subunit activates all 9 isoforms…”
Get full text

Learned helplessness and urinary MHPG levels in unipolar depression by Samson, J A, Mirin, S M, Hauser, S T, Fenton, B T, Schildkraut, J J

“…Studies of the learned helplessness paradigm in laboratory animals show increased central noradrenergic activity following exposure to uncontrollable…”
Get more information

Norepinephrine metabolites as biochemical criteria for classifying depressive disorders and predicting responses to treatment: preliminary findings by Schildkraut, J J

Get more information

Biogenic Amines and Emotion by Schildkraut, Joseph J., Kety, Seymour S.

“…The studies discussed here have shown a fairly consistent relationship between the effects of drugs on biogenic amines, particularly norepinephrine, and…”
Get full text

Clozapine for comorbid substance use disorder and schizophrenia: do patients with schizophrenia have a reward-deficiency syndrome that can be ameliorated by clozapine? by Green, A I, Zimmet, S V, Strous, R D, Schildkraut, J J

“…Alcohol and other drugs of abuse are commonly used by persons with schizophrenia and contribute to the overall morbidity of the disorder. Standard, or typical,…”
Get more information

Turnover and metabolism of norepinephrine in rat brain after 72 hours on a D-deprivation island by Schildkraut, Joseph J., Hartmann, Ernest

Get full text

Enhanced norepinephrine output during longterm desipramine treatment: a possible role for the extraneuronal monoamine transporter (SLC22A3) by Mooney, John J., Samson, Jacqueline A., Hennen, John, Pappalardo, Kathleen, McHale, Nancy, Alpert, Jonathan, Koutsos, Martha, Schildkraut, Joseph J.

“…To study the delay (2–6 weeks) between initial administration of norepinephrine reuptake inhibitor antidepressants and onset of clinical antidepressant action,…”
Get full text

Amphetamine withdrawal: affective state, sleep patterns, and MHPG excretion by Watson, R, Hartmann, E, Schildkraut, J J

Get more information