Search Results - "Schieven, G.L."

p72syk tyrosine kinase is activated by oxidizing conditions that induce lymphocyte tyrosine phosphorylation and Ca2+ signals by SCHIEVEN, G. L, KIRIHARA, J. M, BURG, D. L, GEAHLEN, R. L, LEDBETTER, J. A

“…We have used H2O2 as a pharmacologic agent to examine the effects of oxidizing conditions on lymphocyte signal pathways. Treatment of Ramos cells with 5-10 mM…”
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Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase by KIENER, P. A, RANKIN, B. M, BURKHARDT, A. L, SCHIEVEN, G. L, GILLILAND, L. K, ROWLEY, R. B, BOLEN, J. B, LEDBETTER, J. A

“…Stimulation of the human monocytic cell line THP-1 by cross-linking either Fc gamma receptor I (Fc gamma RI) or Fc gamma receptor II (Fc gamma RII) gave rise…”
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ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction by SCHIEVEN, G. L, MITTLER, R. S, NADLER, S. G, KIRIHARA, J. M, BOLEN, J. B, KANNER, S. B, LEDBETTER, J. A

“…Several mammalian responses to UV irradiation, including the activation of NF-kappa B, are believed to involve tyrosine phosphorylation. UV irradiation and…”
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Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the Pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny by Uckun, F M, Schieven, G L, Dibirdik, I, Chandan-Langlie, M, Tuel-Ahlgren, L, Ledbetter, J A

“…CD40/Bp50 B-cell receptor has been implicated as having an important function for the regulation of human B-cell growth and maturation as well as…”
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Tyrosine phosphorylation of CD19 in pre‐B and mature B cells by Chalupny, N.J., Kanner, S.B., Schieven, G.L., Wee, S.F., Gilliland, L.K., Aruffo, A., Ledbetter, J.A.

“…Cross‐linking of B cell surface immunoglobulins (sIg) results in activation of mature B cells and stimulates a molecular signaling mechanism for…”
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Lymphocyte lineage-restricted tyrosine-phosphorylated proteins that bind PLC gamma 1 SH2 domains by Gilliland, L K, Schieven, G L, Norris, N A, Kanner, S B, Aruffo, A, Ledbetter, J A

“…Epidermal growth factor (EGF) or platelet-derived growth factor binding to their receptor on fibroblasts induces tyrosine phosphorylation of PLC gamma 1 and…”
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Chimeric L6 anti-tumor antibody. Genomic construction, expression, and characterization of the antigen binding site by FELL, H. P, GAYLE, M. A, YELTON, D, LIPSICH, L, SCHIEVEN, G. L, MARKEN, J. S, ARUFFO, A, HELLSTRÖM, K. E, HELLSTRÖM, I, BAJORATH, J

“…We report the cloning of the genomic variable region genes of the human carcinoma reactive murine monoclonal antibody L6 and their genetic linkage to human…”
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Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody by MARKEN, J. S, BAJORATH, J, EDWARDS, C. P, FARR, A. G, SCHIEVEN, G. L, HELLSTRÖM, I, HELLSTRÖM, K. E, ARUFFO, A

“…The murine monoclonal antibody (mAb) L6 recognizes an integral membrane glycoprotein that is highly expressed on lung, breast, colon, and ovarian carcinomas…”
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