Search Results - "Schickli, Jeanne H."

Parainfluenza Virus Type 3 Expressing the Native or Soluble Fusion (F) Protein of Respiratory Syncytial Virus (RSV) Confers Protection from RSV Infection in African Green Monkeys by TANG, Roderick S, MACPHAIL, Mia, SCHICKLI, Jeanne H, KAUR, Jasmine, ROBINSON, Christopher L, LAWLOR, Heather A, GUZZETTA, Jeanne M, SPAETE, Richard R, HALLERT, Aurelia A

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Recovery of Human Metapneumovirus Genetic Lineages A and B from Cloned cDNA by HERFST, Sander, DE GRAAF, Miranda, FOUCHIER, Ron A. M, SCHICKLI, Jeanne H, TANG, Roderick S, KAUR, Jasmine, YANG, Chin-Fen, SPAETE, Richard R, HALLER, Aurelia A, VAN DEN HOOGEN, Bernadette G, OSTERHAUS, Albert D. M. E

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Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design by MacPhail, Mia, Schickli, Jeanne H, Tang, Roderick S, Kaur, Jasmine, Robinson, Christopher, Fouchier, Ron A. M, Osterhaus, Albert D. M. E, Spaete, Richard R, Haller, Aurelia A

“…1 MedImmune Vaccines Inc., 297 North Bernardo Avenue, Mountain View, CA 94043, USA 2 Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands…”
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An S101P Substitution in the Putative Cleavage Motif of the Human Metapneumovirus Fusion Protein Is a Major Determinant for Trypsin-Independent Growth in Vero Cells and Does Not Alter Tissue Tropism in Hamsters by SCHICKLI, Jeanne H, KAUR, Jasmine, ULBRANDT, Nancy, SPAETE, Richard R, TANG, Roderick S

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Effects of Human Metapneumovirus and Respiratory Syncytial Virus Antigen Insertion in Two 3′ Proximal Genome Positions of Bovine/Human Parainfluenza Virus Type 3 on Virus Replication and Immunogenicity by Tang, Roderick S, Schickli, Jeanne H, MacPhail, Mia, Fernandes, Fiona, Bicha, Leenas, Spaete, Joshua, Fouchier, Ron A M, Osterhaus, Albert D M E, Spaete, Richard, Haller, Aurelia A

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Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters by Schickli, Jeanne H, Kaur, Jasmine, Macphail, Mia, Guzzetta, Jeanne M, Spaete, Richard R, Tang, Roderick S

“…Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are…”
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The N-Terminal Region of the Murine Coronavirus Spike Glycoprotein Is Associated with the Extended Host Range of Viruses from Persistently Infected Murine Cells by SCHICKLI, Jeanne H, THACKRAY, Larissa B, SAWICKI, Stanley G, HOLMES, Kathryn V

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Palivizumab epitope-displaying virus-like particles protect rodents from RSV challenge by Schickli, Jeanne H, Whitacre, David C, Tang, Roderick S, Kaur, Jasmine, Lawlor, Heather, Peters, Cory J, Jones, Joyce E, Peterson, Darrell L, McCarthy, Michael P, Van Nest, Gary, Milich, David R

“…Respiratory syncytial virus (RSV) is the most common cause of serious viral bronchiolitis in infants, young children, and the elderly. Currently, there is not…”
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Nonclinical phenotypic and genotypic analyses of a Phase 1 pediatric respiratory syncytial virus vaccine candidate MEDI-559 (rA2cp248/404/1030ΔSH) at permissive and non-permissive temperatures by Schickli, Jeanne H., Kaur, Jasmine, Tang, Roderick S.

“…► RSV vaccine MEDI-559 has 39 nt silent differences compared to a previous candidate. ► Variants of temperature-sensitive (ts) MEDI-559 can occur at elevated…”
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A single amino acid in the F2 subunit of respiratory syncytial virus fusion protein alters growth and fusogenicity by Lawlor, Heather A, Schickli, Jeanne H, Tang, Roderick S

“…Respiratory syncytial virus (RSV) causes severe lower respiratory tract infection in children, especially in infants less than 1 year of age. There are…”
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Implication of respiratory syncytial virus (RSV) F transgene sequence heterogeneity observed in Phase 1 evaluation of MEDI-534, a live attenuated parainfluenza type 3 vectored RSV vaccine by Yang, Chin-Fen, Wang, C. Kathy, Malkin, Elissa, Schickli, Jeanne H, Shambaugh, Cindy, Zuo, Fengrong, Galinski, Mark S, Dubovsky, Filip, Tang, Roderick S

“…Highlights • The live RSV vaccine virus was primarily detected in young children post dose 1. • About half of the shed vaccine viruses (13/24) contained…”
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Conformational Changes in the Spike Glycoprotein of Murine Coronavirus Are Induced at 37°C either by Soluble Murine CEACAM1 Receptors or by pH 8 by Zelus, Bruce D., Schickli, Jeanne H., Blau, Dianna M., Weiss, Susan R., Holmes, Kathryn V.

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A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys by Tang, Roderick S., Mahmood, Kutubuddin, MacPhail, Mia, Guzzetta, Jeanne M., Haller, Aurelia A., Liu, Hui, Kaur, Jasmine, Lawlor, Heather A., Stillman, Elizabeth A., Schickli, Jeanne H., Fouchier, Ron A.M., Osterhaus, Albert D.M.E., Spaete, Richard R.

“…Human metapneumovirus (hMPV) infection causes respiratory tract disease similar to that observed during human respiratory syncytial virus infection (hRSV)…”
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Evaluation of attenuation, immunogenicity and efficacy of a bovine parainfluenza virus type 3 (PIV-3) vaccine and a recombinant chimeric bovine/human PIV-3 vaccine vector in rhesus monkeys by Pennathur, Sridhar, Haller, Aurelia A, MacPhail, Mia, Rizzi, Tom, Kaderi, Sepideh, Fernandes, Fiona, Bicha, Leenas, Schickli, Jeanne H, Tang, Roderick S, Chen, Wendy, Nguyen, Nick, Mathie, Sharon, Mehta, Hersh, Coelingh, Kathleen L

“…MedImmune Vaccines Inc., 297 North Bernardo Avenue, Mountain View, CA 94043, USA Correspondence Sridhar Pennathur pennathurs{at}medimmune.com Restricted…”
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Challenges in developing a pediatric RSV vaccine by Schickli, Jeanne H., Dubovsky, Filip, Tang, Roderick S.

“…RSV bronchiolitis is the leading cause of infant hospitalization in industrialized countries.  There is an unmet need to prevent RSV lower respiratory tract…”
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Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8 by Zelus, Bruce D, Schickli, Jeanne H, Blau, Dianna M, Weiss, Susan R, Holmes, Kathryn V

“…The spike glycoprotein (S) of the murine coronavirus mouse hepatitis virus (MHV) binds to viral murine CEACAM receptor glycoproteins and causes membrane…”
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The murine coronavirus mouse hepatitis virus strain A59 from persistently infected murine cells exhibits an extended host range by Schickli, J H, Zelus, B D, Wentworth, D E, Sawicki, S G, Holmes, K V

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Receptor specificity and receptor-induced conformational changes in mouse hepatitis virus spike glycoprotein by Holmes, K V, Zelus, B D, Schickli, J H, Weiss, S R

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Selection in persistently infected murine cells of an MHV-A59 variant with extended host range by Schickli, J H, Wentworth, D E, Zelus, B D, Holmes, K V, Sawicki, S G

“…Murine coronavirus MHV-A59 normally infects only murine cells in vitro and causes transmissible infection only in mice. In the 17 C1 1 line of murine cells,…”
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