Search Results - "Schickli, J H"

Plasmid-only rescue of influenza A virus vaccine candidates by Schickli, J. H., Flandorfer, A., Nakaya, T., Martinez-Sobrido, L., García-Sastre, A., Palese, P.

“…The potential threat of another influenza virus pandemic stimulates discussion on how to prepare for such an event. The most reasonable prophylactic approach…”
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Optimization of plasmid-only rescue of highly attenuated and temperature-sensitive respiratory syncytial virus (RSV) vaccine candidates for human trials by Kaur, J., Tang, R.S., Spaete, R.R., Schickli, J.H.

“…Respiratory syncytial virus (RSV) is the most common cause of severe bronchiolitis in infants and young children in the US. No licensed RSV vaccines are…”
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The murine coronavirus mouse hepatitis virus strain A59 from persistently infected murine cells exhibits an extended host range by Schickli, J H, Zelus, B D, Wentworth, D E, Sawicki, S G, Holmes, K V

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A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys by Tang, Roderick S., Mahmood, Kutubuddin, MacPhail, Mia, Guzzetta, Jeanne M., Haller, Aurelia A., Liu, Hui, Kaur, Jasmine, Lawlor, Heather A., Stillman, Elizabeth A., Schickli, Jeanne H., Fouchier, Ron A.M., Osterhaus, Albert D.M.E., Spaete, Richard R.

“…Human metapneumovirus (hMPV) infection causes respiratory tract disease similar to that observed during human respiratory syncytial virus infection (hRSV)…”
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Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design by MacPhail, Mia, Schickli, Jeanne H, Tang, Roderick S, Kaur, Jasmine, Robinson, Christopher, Fouchier, Ron A. M, Osterhaus, Albert D. M. E, Spaete, Richard R, Haller, Aurelia A

“…1 MedImmune Vaccines Inc., 297 North Bernardo Avenue, Mountain View, CA 94043, USA 2 Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands…”
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Effects of Human Metapneumovirus and Respiratory Syncytial Virus Antigen Insertion in Two 3′ Proximal Genome Positions of Bovine/Human Parainfluenza Virus Type 3 on Virus Replication and Immunogenicity by Tang, Roderick S, Schickli, Jeanne H, MacPhail, Mia, Fernandes, Fiona, Bicha, Leenas, Spaete, Joshua, Fouchier, Ron A M, Osterhaus, Albert D M E, Spaete, Richard, Haller, Aurelia A

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Evaluation of attenuation, immunogenicity and efficacy of a bovine parainfluenza virus type 3 (PIV-3) vaccine and a recombinant chimeric bovine/human PIV-3 vaccine vector in rhesus monkeys by Pennathur, Sridhar, Haller, Aurelia A, MacPhail, Mia, Rizzi, Tom, Kaderi, Sepideh, Fernandes, Fiona, Bicha, Leenas, Schickli, Jeanne H, Tang, Roderick S, Chen, Wendy, Nguyen, Nick, Mathie, Sharon, Mehta, Hersh, Coelingh, Kathleen L

“…MedImmune Vaccines Inc., 297 North Bernardo Avenue, Mountain View, CA 94043, USA Correspondence Sridhar Pennathur pennathurs{at}medimmune.com Restricted…”
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Implication of respiratory syncytial virus (RSV) F transgene sequence heterogeneity observed in Phase 1 evaluation of MEDI-534, a live attenuated parainfluenza type 3 vectored RSV vaccine by Yang, Chin-Fen, Wang, C. Kathy, Malkin, Elissa, Schickli, Jeanne H, Shambaugh, Cindy, Zuo, Fengrong, Galinski, Mark S, Dubovsky, Filip, Tang, Roderick S

“…Highlights • The live RSV vaccine virus was primarily detected in young children post dose 1. • About half of the shed vaccine viruses (13/24) contained…”
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Receptor specificity and receptor-induced conformational changes in mouse hepatitis virus spike glycoprotein by Holmes, K V, Zelus, B D, Schickli, J H, Weiss, S R

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Selection in persistently infected murine cells of an MHV-A59 variant with extended host range by Schickli, J H, Wentworth, D E, Zelus, B D, Holmes, K V, Sawicki, S G

“…Murine coronavirus MHV-A59 normally infects only murine cells in vitro and causes transmissible infection only in mice. In the 17 C1 1 line of murine cells,…”
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Conformational Changes in the Spike Glycoprotein of Murine Coronavirus Are Induced at 37 degree C either by Soluble Murine CEACAM1 Receptors or by pH 8 by Zelus, B D, Schickli, J H, Blau, D M, Weiss, SR, Holmes, K V

“…The spike glycoprotein (S) of the murine coronavirus mouse hepatitis virus (MHV) binds to viral murine CEACAM receptor glycoproteins and causes membrane…”
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Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8 by Zelus, Bruce D, Schickli, Jeanne H, Blau, Dianna M, Weiss, Susan R, Holmes, Kathryn V

“…The spike glycoprotein (S) of the murine coronavirus mouse hepatitis virus (MHV) binds to viral murine CEACAM receptor glycoproteins and causes membrane…”
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Parainfluenza Virus Type 3 Expressing the Native or Soluble Fusion (F) Protein of Respiratory Syncytial Virus (RSV) Confers Protection from RSV Infection in African Green Monkeys by TANG, Roderick S, MACPHAIL, Mia, SCHICKLI, Jeanne H, KAUR, Jasmine, ROBINSON, Christopher L, LAWLOR, Heather A, GUZZETTA, Jeanne M, SPAETE, Richard R, HALLERT, Aurelia A

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Recovery of Human Metapneumovirus Genetic Lineages A and B from Cloned cDNA by HERFST, Sander, DE GRAAF, Miranda, FOUCHIER, Ron A. M, SCHICKLI, Jeanne H, TANG, Roderick S, KAUR, Jasmine, YANG, Chin-Fen, SPAETE, Richard R, HALLER, Aurelia A, VAN DEN HOOGEN, Bernadette G, OSTERHAUS, Albert D. M. E

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An S101P Substitution in the Putative Cleavage Motif of the Human Metapneumovirus Fusion Protein Is a Major Determinant for Trypsin-Independent Growth in Vero Cells and Does Not Alter Tissue Tropism in Hamsters by SCHICKLI, Jeanne H, KAUR, Jasmine, ULBRANDT, Nancy, SPAETE, Richard R, TANG, Roderick S

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The N-Terminal Region of the Murine Coronavirus Spike Glycoprotein Is Associated with the Extended Host Range of Viruses from Persistently Infected Murine Cells by SCHICKLI, Jeanne H, THACKRAY, Larissa B, SAWICKI, Stanley G, HOLMES, Kathryn V

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