Search Results - "Schick, Bernhard"
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Survey on Scenario-Based Safety Assessment of Automated Vehicles
Published in IEEE access (2020)“…When will automated vehicles come onto the market? This question has puzzled the automotive industry and society for years. The technology and its…”
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Fully automatic segmentation of glottis and vocal folds in endoscopic laryngeal high-speed videos using a deep Convolutional LSTM Network
Published in PloS one (10-02-2020)“…The objective investigation of the dynamic properties of vocal fold vibrations demands the recording and further quantitative analysis of laryngeal high-speed…”
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Let’s talk about Secs: Sec61, Sec62 and Sec63 in signal transduction, oncology and personalized medicine
Published in Signal transduction and targeted therapy (28-04-2017)“…The heterotrimeric Sec61 complex and the dimeric Sec62/Sec63 complex are located in the membrane of the human endoplasmic reticulum (ER) and play a central…”
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Neural Crest Stem Cells in Juvenile Angiofibromas
Published in International journal of molecular sciences (09-02-2022)“…The etiology of juvenile angiofibroma (JA) has been a controversial topic for more than 160 years. Numerous theories have been proposed to explain this rare…”
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Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ-A Novel CT-Guided Approach to the Cochlea
Published in International journal of molecular sciences (26-05-2023)“…TRPC channels are critical players in cochlear hair cells and sensory neurons, as demonstrated in animal experiments. However, evidence for TRPC expression in…”
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Model Validation and Scenario Selection for Virtual-Based Homologation of Automated Vehicles
Published in Applied sciences (01-01-2021)“…Due to the rapid progress in the development of automated vehicles over the last decade, their market entry is getting closer. One of the remaining challenges…”
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Optoacoustically induced auditory brainstem responses in the mouse model enhanced through an absorbing film
Published in Journal of biomedical optics (01-09-2021)“…Significance: Optoacoustic stimulation offers an alternative stimulation strategy for the hearing organ. To serve as the base for a novel auditory prosthesis,…”
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α2δ2 Controls the Function and Trans-Synaptic Coupling of Cav1.3 Channels in Mouse Inner Hair Cells and Is Essential for Normal Hearing
Published in The Journal of neuroscience (26-10-2016)“…The auxiliary subunit α δ2 modulates the abundance and function of voltage-gated calcium channels. Here we show that α δ2 mRNA is expressed in neonatal and…”
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Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
Published in Journal of biomedical optics (01-03-2021)“…Significance: Optoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing…”
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Differential nasal swab cytology represents a valuable tool for therapy monitoring but not prediction of therapy response in chronic rhinosinusitis with nasal polyps treated with Dupilumab
Published in Frontiers in immunology (18-04-2023)“…Chronic Rhinosinusitis with nasal polyps (CRSwNP) is a common chronic disease with a high impact on patients' quality of life. If conservative and surgical…”
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Cytotoxicity studies of an optoacoustic stimulation strategy for the development of laser-based hearing aids
Published in Journal of biomedical optics (01-06-2020)“…Significance: Worldwide, ∼460 million people suffer from disabling hearing impairment. Many of these patients are still not sufficiently supplied with…”
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Effects of Vitamin D on tumor cell proliferation and migration, tumor initiation and anti-tumor immune response in head and neck squamous cell carcinomas
Published in Biomedicine & pharmacotherapy (01-11-2024)“…Head and neck squamous cell carcinomas (HNSCCs) are among the six most common cancers, with a constantly poor prognosis. Vitamin D has been found to have…”
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Alterations in pathogen-specific cellular and humoral immunity associated with acute peripheral facial palsy of infectious origin
Published in Journal of neuroinflammation (25-10-2023)“…Abstract Background Peripheral facial palsy (PFP) is a common neurologic symptom which can be triggered by pathogens, autoimmunity, trauma, tumors,…”
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Prognostic impact of intra- and peritumoral immune cell subpopulations in head and neck squamous cell carcinomas - comprehensive analysis of the TCGA-HNSC cohort and immunohistochemical validation on 101 patients
Published in Frontiers in immunology (13-06-2023)“…Due to the expanding role of immune checkpoint inhibition in the treatment of head and neck squamous cell carcinoma, understanding immunological processes in…”
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Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer
Published in Frontiers in physiology (15-08-2022)“…Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among…”
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Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets
Published in BMC biology (26-09-2018)“…Perineuronal nets (PNNs) are specialized aggregations of extracellular matrix (ECM) molecules surrounding specific neurons in the central nervous system (CNS)…”
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Vitamin D deficiency in head and neck cancer patients - prevalence, prognostic value and impact on immune function
Published in Oncoimmunology (02-09-2018)“…Vitamin D deficiency is frequently observed in human cancer patients and a prognostic relevance could be shown for some entities. Additionally, it is known…”
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Complete remission of an early-stage laryngeal cancer under combined pembrolizumab and chemotherapy treatment of a synchronous lung adenocarcinoma
Published in Journal of otolaryngology-head and neck surgery (16-05-2022)“…Anti-PD1-Checkpoint inhibition (CI) is an established treatment of recurrent and/or metastatic head and neck cancer. A potential benefit from CI in early-stage…”
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First biocompatibility margins for optical stimulation at the eardrum via 532-nm laser pulses in a mouse model
Published in Journal of biomedical optics (01-08-2019)“…Hearing impairment affects ∼460 million people worldwide. Conservative therapies, such as hearing aids, bone conduction systems, and middle ear implants, do…”
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