Search Results - "Schiavoni, Giovanna"

Eosinophils: The unsung heroes in cancer? by Varricchi, Gilda, Galdiero, Maria Rosaria, Loffredo, Stefania, Lucarini, Valeria, Marone, Giancarlo, Mattei, Fabrizio, Marone, Gianni, Schiavoni, Giovanna

“…Prolonged low-grade inflammation or smoldering inflammation is a hallmark of a cancer. Eosinophils are components of the immune microenvironment that modulates…”
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The dangerous liaison between pollens and pollution in respiratory allergy by Schiavoni, Giovanna, BS, D'Amato, Gennaro, MD, Afferni, Claudia, BS

“…Abstract Objective To recapitulate the more recent epidemiologic studies on the association of air pollution with respiratory allergic diseases prevalence and…”
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IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils by Lucarini, Valeria, Ziccheddu, Giovanna, Macchia, Iole, La Sorsa, Valentina, Peschiaroli, Francesca, Buccione, Carla, Sistigu, Antonella, Sanchez, Massimo, Andreone, Sara, D'Urso, Maria Teresa, Spada, Massimo, Macchia, Daniele, Afferni, Claudia, Mattei, Fabrizio, Schiavoni, Giovanna

“…The alarmin IL-33 is an IL-1 family member that stimulates pleiotropic immune reactions depending on the target tissue and microenvironmental factors. In this…”
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Editorial: Emerging Roles for Type 2-Associated Cells and Cytokines in Cancer Immunity by Schiavoni, Giovanna, Munitz, Ariel, Strid, Jessica

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Type I Interferons as Stimulators of DC-Mediated Cross-Priming: Impact on Anti-Tumor Response by Schiavoni, Giovanna, Mattei, Fabrizio, Gabriele, Lucia

“…Induction of potent tumor-specific cytotoxic T-cell responses is a fundamental objective in anticancer therapeutic strategies. This event requires that…”
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Eosinophils as potential biomarkers in respiratory viral infections by Macchia, Iole, La Sorsa, Valentina, Urbani, Francesca, Moretti, Sonia, Antonucci, Caterina, Afferni, Claudia, Schiavoni, Giovanna

“…Eosinophils are bone marrow-derived granulocytes that, under homeostatic conditions, account for as much as 1-3% of peripheral blood leukocytes. During…”
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The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity by Afferni, Claudia, Buccione, Carla, Andreone, Sara, Galdiero, Maria Rosaria, Varricchi, Gilda, Marone, Gianni, Mattei, Fabrizio, Schiavoni, Giovanna

“…Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of…”
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The tumor microenvironment: a pitch for multiple players by Schiavoni, Giovanna, Gabriele, Lucia, Mattei, Fabrizio

“…The cancer microenvironment may be conceptually regarded as a pitch where the main players are resident and non-resident cellular components, each covering a…”
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Basophils from allergy to cancer by Poto, Remo, Gambardella, Adriana Rosa, Marone, Gianni, Schroeder, John T, Mattei, Fabrizio, Schiavoni, Giovanna, Varricchi, Gilda

“…Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies,…”
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Anti-Tumorigenic Activities of IL-33: A Mechanistic Insight by Andreone, Sara, Gambardella, Adriana Rosa, Mancini, Jacopo, Loffredo, Stefania, Marcella, Simone, La Sorsa, Valentina, Varricchi, Gilda, Schiavoni, Giovanna, Mattei, Fabrizio

“…Interleukin-33 (IL-33) is an epithelial-derived cytokine that can be released upon tissue damage, stress, or infection, acting as an alarmin for the immune…”
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Is There a Role for Basophils in Cancer? by Marone, Giancarlo, Schroeder, John T, Mattei, Fabrizio, Loffredo, Stefania, Gambardella, Adriana Rosa, Poto, Remo, de Paulis, Amato, Schiavoni, Giovanna, Varricchi, Gilda

“…Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes. During…”
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Combining Type I Interferons and 5-Aza-2′-Deoxycitidine to Improve Anti-Tumor Response against Melanoma by Lucarini, Valeria, Buccione, Carla, Ziccheddu, Giovanna, Peschiaroli, Francesca, Sestili, Paola, Puglisi, Rossella, Mattia, Gianfranco, Zanetti, Cristiana, Parolini, Isabella, Bracci, Laura, Macchia, Iole, Rossi, Alessandra, D'Urso, Maria Teresa, Macchia, Daniele, Spada, Massimo, De Ninno, Adele, Gerardino, Annamaria, Mozetic, Pamela, Trombetta, Marcella, Rainer, Alberto, Businaro, Luca, Schiavoni, Giovanna, Mattei, Fabrizio

“…Resistance to IFN-I–induced antineoplastic effects has been reported in many tumors and arises, in part, from epigenetic silencing of IFN-stimulated genes by…”
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Chlamydia pneumoniae-Mediated Inflammation in Atherosclerosis: A Meta-Analysis by Schiavoni, Giovanna, Farcomeni, Alessio, Di Pietro, Marisa, Filardo, Simone, Sessa, Rosa

“…Several studies have attempted to relate the C. pneumoniae-mediated inflammatory state with atherosclerotic cardiovascular diseases, providing inconsistent…”
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Differential Effects of Alarmins on Human and Mouse Basophils by Gambardella, Adriana R, Poto, Remo, Tirelli, Valentina, Schroeder, John T, Marone, Gianni, Mattei, Fabrizio, Varricchi, Gilda, Schiavoni, Giovanna

“…Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of…”
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High-throughput analysis of cell-cell crosstalk in ad hoc designed microfluidic chips for oncoimmunology applications by Mencattini, Arianna, De Ninno, Adele, Mancini, Jacopo, Businaro, Luca, Martinelli, Eugenio, Schiavoni, Giovanna, Mattei, Fabrizio

“…Understanding the interactions between immune and cancer cells occurring within the tumor microenvironment is a prerequisite for successful and personalized…”
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From Petri Dishes to Organ on Chip Platform: The Increasing Importance of Machine Learning and Image Analysis by Mencattini, Arianna, Mattei, Fabrizio, Schiavoni, Giovanna, Gerardino, Annamaria, Businaro, Luca, Di Natale, Corrado, Martinelli, Eugenio

“…The increasing interest for microfluidic devices in medicine and biology has opened the way to new time-lapse microscopy era where the amount of images and…”
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Oncoimmunology Meets Organs-on-Chip by Mattei, Fabrizio, Andreone, Sara, Mencattini, Arianna, De Ninno, Adele, Businaro, Luca, Martinelli, Eugenio, Schiavoni, Giovanna

“…Oncoimmunology represents a biomedical research discipline coined to study the roles of immune system in cancer progression with the aim of discovering novel…”
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IL-33 stimulates the anticancer activities of eosinophils through extracellular vesicle-driven reprogramming of tumor cells by Gambardella, Adriana Rosa, Antonucci, Caterina, Zanetti, Cristiana, Noto, Francesco, Andreone, Sara, Vacca, Davide, Pellerito, Valentina, Sicignano, Chiara, Parrottino, Giuseppe, Tirelli, Valentina, Tinari, Antonella, Falchi, Mario, De Ninno, Adele, Businaro, Luca, Loffredo, Stefania, Varricchi, Gilda, Tripodo, Claudio, Afferni, Claudia, Parolini, Isabella, Mattei, Fabrizio, Schiavoni, Giovanna

“…Immune cell-derived extracellular vesicles (EV) affect tumor progression and hold promise for therapeutic applications. Eosinophils are major effectors in…”
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Type I Interferons Potently Enhance Humoral Immunity and Can Promote Isotype Switching by Stimulating Dendritic Cells In Vivo by Le Bon, Agnes, Schiavoni, Giovanna, D'Agostino, Giuseppina, Gresser, Ion, Belardelli, Filippo, Tough, David F.

“…Type I interferons (IFN-I) are rapidly induced following infection and play a key role in nonspecific inhibition of virus replication. Here we have…”
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Trogocytosis in innate immunity to cancer is an intimate relationship with unexpected outcomes by Mattei, Fabrizio, Andreone, Sara, Spadaro, Francesca, Noto, Francesco, Tinari, Antonella, Falchi, Mario, Piconese, Silvia, Afferni, Claudia, Schiavoni, Giovanna

“…Trogocytosis is a cellular process whereby a cell acquires a membrane fragment from a donor cell in a contact-dependent manner allowing for the transfer of…”
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