Search Results - "Schiavo, Andrea"
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Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes
Published in Nucleic acids research (02-11-2018)“…Abstract Transfer RNAs (tRNAs) are non-coding RNA molecules essential for protein synthesis. Post-transcriptionally they are heavily modified to improve their…”
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2
Cryptic species and host specificity in the bryozoan-associated hydrozoan Zanclea divergens (Hydrozoa, Zancleidae)
Published in Molecular phylogenetics and evolution (01-10-2020)“…[Display omitted] •Z. divergens is a species complex associated with bryozoan genus Celleporaria.•General morphology is not informative.•Statistical treatment…”
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3
Green Fluorescence Patterns in Closely Related Symbiotic Species of Zanclea (Hydrozoa, Capitata)
Published in Diversity (Basel) (01-02-2020)“…Green fluorescence is a common phenomenon in marine invertebrates and is caused by green fluorescent proteins. Many hydrozoan species display fluorescence in…”
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4
Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
Published in Stem cell research & therapy (03-01-2020)“…Adult human pancreatic beta cells are the "gold standard" for studies on diabetes pathogenesis, but their use is limited by insufficient availability and…”
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5
Validation of a targeted next-generation sequencing panel for pancreatic ductal adenocarcinomas
Published in Experimental and molecular pathology (01-10-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is reported to be amongst the cancers with the lowest survival rate at 5 years. In the present study we aimed to…”
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6
The Role of SMAD4 Inactivation in Epithelial-Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?
Published in Cancers (15-02-2022)“…Pancreatic ductal adenocarcinoma (PDAC) presents a five-year survival rate of 10% and its incidence increases over the years. It is, therefore, essential to…”
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7
SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature
Published in Acta neuropathologica communications (10-05-2023)“…COVID-19-infected patients harbour neurological symptoms such as stroke and anosmia, leading to the hypothesis that there is direct invasion of the central…”
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8
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
Published in Frontiers in cell and developmental biology (17-08-2022)“…differentiation of human induced pluripotent stem cells (iPSCs) into beta cells represents an important cell source for diabetes research. Here, we fully…”
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The miRNAs miR-211-5p and miR-204-5p modulate ER stress in human beta cells
Published in Journal of molecular endocrinology (01-08-2019)“…miRNAs are a class of small non-coding RNAs that regulate gene expression. Type 1 diabetes is an autoimmune disease characterized by insulitis (islets…”
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10
Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
Published in Oncogene (12-01-2024)“…Thyroid cancer is the most common endocrine malignancy and several genetic events have been described to promote the development of thyroid carcinogenesis…”
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11
Systematics and character evolution of capitate hydrozoans
Published in Cladistics (01-04-2024)“…Capitate hydrozoans are a morphologically and ecologically diverse hydrozoan suborder, currently including about 200 species. Being grouped in two clades,…”
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12
Generation of Functional Thyroid Tissue Using 3D-Based Culture of Embryonic Stem Cells
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…During the last decade three-dimensional (3D) cultures of pluripotent stem cells have been intensively used to understand morphogenesis and molecular signaling…”
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13
The microRNAs miR-211-5p and miR-204-5p modulate ER stress in human beta cells
Published in Journal of molecular endocrinology (01-08-2019)“…MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression. Type 1 diabetes is an autoimmune disease characterized by insulits…”
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14
Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice
Published in Stem cells (Dayton, Ohio) (01-08-2012)“…Slow T‐cell reconstitution is a major clinical concern after transplantation of cord blood (CB)‐derived hematopoietic stem cells. Adoptive transfer of in…”
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15
Inferring regulators of cell identity in the human adult pancreas
Published in NAR genomics and bioinformatics (01-09-2023)“…Abstract Cellular identity during development is under the control of transcription factors that form gene regulatory networks. However, the transcription…”
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16
Endothelial properties of third-trimester amniotic fluid stem cells cultured in hypoxia
Published in Stem cell research & therapy (31-10-2015)“…Endothelial dysfunction is found in different pathologies such as diabetes and renal and heart diseases, representing one of the major health problems. The…”
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In Vitro Exposure to DL-4 Increases the in Vitro and In Vivo T-Lymphopoietic Potential of CB Derived CD34+ Progenitor Cells
Published in Blood (18-11-2011)“…Abstract 2980 Notchligand-based culture systems such as OP9-DL1 cells induce HSC to engage towards the T-cell developmental program and allow generation of…”
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18
Further Characterization of T-Cellular Precursors Generated From CD34+ Progenitors by Exposure to Immobilized Notch Ligand Delta-Like 4 In Vitro
Published in Blood (19-11-2010)“…Abstract 3712 Injection of donor derived T-cellular precursors has been proposed as a novel strategy to shorten delayed reconstitution of the T-lymphoid…”
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19
Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/[gamma]c-/- Mice
Published in Stem cells (Dayton, Ohio) (01-08-2012)“…Slow T-cell reconstitution is a major clinical concern after transplantation of cord blood (CB)-derived hematopoietic stem cells. Adoptive transfer of in…”
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20
Isolation of c-Kit+ human amniotic fluid stem cells from second trimester
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Amniotic fluid-derived stem (AFS) cells have been described as an appealing source of stem cells because of their (1) fetal, non-embryonic origin, (2) easy…”
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