Search Results - "Schewe, T."

15-lipoxygenase-1: a prooxidant enzyme by Schewe, Tankred

“…Human and rabbit reticulocyte 15-lipoxygenase (15-lipoxygenase-1) and the leukocyte-type 12-lipoxygenases (12/15-lipoxygenases) of pig, beef, mouse and rat…”
Get more information

Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles by Winkler, K., Schewe, T., Pütz, G., Ödünc, N., Schäfer, G., Siegel, E., Geisen, U., Abletshauser, C., Hoffmann, M. M.

“…Background  Patients with metabolic syndrome (MS) and type 2 diabetes (T2DM) show increased risk for coronary artery disease. Lipoprotein metabolism is…”
Get full text

Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism by Sutherland, M, Shankaranarayanan, P, Schewe, T, Nigam, S

“…The 12-lipoxygenase pathway of arachidonic acid metabolism in platelets and other cells is bifurcated into a reduction route yielding…”
Get full text

Biological dynamics and distribution of 3-hydroxy fatty acids in the yeast Dipodascopsis uninucleata as investigated by immunofluorescence microscopy. Evidence for a putative regulatory role in the sexual reproductive cycle by Kock, J.L.F, Venter, P, Linke, D, Schewe, T, Nigam, S

“…Dipodascopsis uninucleata has been recently shown to produce 3-hydroxy polyenoic fatty acids from several exogenous polyenoic fatty acids. In order to examine…”
Get full text

Phospholipase A(2)s and lipid peroxidation by Nigam, S, Schewe, T

“…Lipid peroxidation of membrane phospholipids can proceed both enzymatically via the mammalian 15-lipoxygenase-1 or the NADPH-cytochrome P-450 reductase system…”
Get more information

Production of 3R-hydroxy-polyenoic fatty acids by the yeast Dipodascopsis uninucleata by Venter, P, Kock, J.L.F, Kumar, G.S, Botha, A, Coetzee, D.J, Botes, P.J, Bhatt, R.K, Falck, J.R, Schewe, T, Nigam, S

“…Various fatty acids were fed to the yeast Dipodascopsis uninucleata UOFS Y 128, and the extracted samples were analyzed for the accumulation of 3‐hydroxy…”
Get full text

Inhibition of 15-lipoxygenases by flavonoids: structure–activity relations and mode of action by Sadik, Christian David, Sies, Helmut, Schewe, Tankred

“…We have recently reported that flavonoids of cocoa inhibit the mammalian 15-lipoxygenase-1—a catalyst of enzymatic lipid peroxidation. To elucidate the…”
Get full text

Vascular Effects of Cocoa Rich in Flavan-3-ols by Heiss, Christian, Dejam, André, Kleinbongard, Petra, Schewe, Tankred, Sies, Helmut, Kelm, Malte

Get full text

Analysis of the stereochemistry of lipoxygenase-derived hydroxypolyenoic fatty acids by means of chiral phase high-pressure liquid chromatography by Kühn, H, Wiesner, R, Lankin, V Z, Nekrasov, A, Alder, L, Schewe, T

“…A chiral phase HPLC method was developed for the simultaneous determination of the positional and optical isomers of the lipoxygenase-derived hydroxypolyenoic…”
Get more information

Cocoa polyphenols and inflammatory mediators by Sies, Helmut, Schewe, Tankred, Heiss, Christian, Kelm, Malte

“…Cocoa products are sources of flavan-3-ols, which have attracted interest regarding cardiovascular health. This review provides a survey of our research on the…”
Get full text

Flavanol-rich cocoa drink lowers plasma F 2 -isoprostane concentrations in humans by Wiswedel, Ingrid, Hirsch, Daniela, Kropf, Siegfried, Gruening, Martin, Pfister, Eberhard, Schewe, Tankred, Sies, Helmut

Get full text

Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase by Schewe, Tankred, Kühn, Hartmut, Sies, Helmut

“…(-)-Epicatechin and its related oligomers, the procyanidins, are present in sizable amounts in some cocoas and chocolates. Intake of flavonoid-rich chocolate…”
Get more information

Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid by Bryant, R W, Bailey, J M, Schewe, T, Rapoport, S M

Get full text

Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4 by Bryant, R W, Schewe, T, Rapoport, S M, Bailey, J M

“…The purified lipoxygenase of rabbit reticulocytes converts arachidonic acid at 0 degrees C to 15-hydroperoxyeicosatetraenoic acid (15-HPETE) and to…”
Get full text

Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases by Schewe, T, Rapoport, S M, Kühn, H

Get more information

The maturational breakdown of mitochondria in reticulocytes by Rapoport, S M, Schewe, T

Get more information

Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase by Steffen, Yvonne, Schewe, Tankred, Sies, Helmut

“…Intake of flavanol-rich food or beverages was previously shown to ameliorate endothelial function and to enhance bioactivity of nitric oxide with individuals…”
Get full text

The stereochemistry of the reactions of lipoxygenases and their metabolites. Proposed nomenclature of lipoxygenases and related enzymes by Kühn, H, Schewe, T, Rapoport, S M

Get more information

A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria by Schewe, T., Halangk, W., Hiebsch, Ch, Rapoport, S.M.

Get full text

Myeloperoxidase/nitrite-mediated lipid peroxidation of low-density lipoprotein as modulated by flavonoids by Kostyuk, Vladimir A., Kraemer, Tilo, Sies, Helmut, Schewe, Tankred

“…In the presence of a H2O2-generating system, myeloperoxidase (MPO) caused conjugated diene formation in low-density lipoprotein (LDL), indicating lipid…”
Get full text