Search Results - "Schewe, Hendrik"

Investigation of monoterpenoid resistance mechanisms in Pseudomonas putida and their consequences for biotransformations by Schempp, Florence Miramella, Hofmann, Katharina Elisabeth, Mi, Jia, Kirchner, Ferdinand, Meffert, Annika, Schewe, Hendrik, Schrader, Jens, Buchhaupt, Markus

“…Monoterpenoids are widely used in industrial applications, e.g. as active ingredients in pharmaceuticals, in flavor and fragrance compositions, and in…”
Get full text

De novo production of the monoterpenoid geranic acid by metabolically engineered Pseudomonas putida by Mi, Jia, Becher, Daniela, Lubuta, Patrice, Dany, Sarah, Tusch, Kerstin, Schewe, Hendrik, Buchhaupt, Markus, Schrader, Jens

“…Production of monoterpenoids as valuable chemicals using recombinant microbes is a growing field of interest. Unfortunately, antimicrobial activity of most…”
Get full text

High concentrations of biotechnologically produced astaxanthin by lowering pH in a Phaffia rhodozyma bioprocess by Schewe, Hendrik, Kreutzer, Andrea, Schmidt, Isabell, Schubert, Christian, Schrader, Jens

“…Astaxanthin additions to animal diets predominantly serve as colorization aid to satisfy consumer expectations and desire for a consistent product with…”
Get full text

Multiple improvement of astaxanthin biosynthesis in Xanthophyllomyces dendrorhous by a combination of conventional mutagenesis and metabolic pathway engineering by Gassel, Sören, Schewe, Hendrik, Schmidt, Isabell, Schrader, Jens, Sandmann, Gerhard

“…Xanthophyllomyces dendrorhous (Phaffia rhodozyma) is the only yeast or fungus that synthesizes the commercially attractive carotenoid astaxanthin. For a…”
Get full text

Investigation of fatty aldehyde and alcohol synthesis from fatty acids by αDox- or CAR-expressing Escherichia coli by Maurer, Susanne, Schewe, Hendrik, Schrader, Jens, Buchhaupt, Markus

“…•Aldehyde/alcohol ratios differ largely in αDox- or CAR-catalyzed biotransformations.•Catabolic redox state of CAR-expressing probably the reason for the high…”
Get full text

P450(BM-3)-catalyzed whole-cell biotransformation of alpha-pinene with recombinant Escherichia coli in an aqueous-organic two-phase system by Schewe, Hendrik, Holtmann, Dirk, Schrader, Jens

“…A recombinant Escherichia coli BL21 (DE3) strain overexpressing a variant of P450(BM-3) (V26T/R47F/A74G/F87V/L188K; abbreviated: BL21 (P450(BM-3) QM))…”
Get full text

Biotechnological production of astaxanthin with Phaffia rhodozyma/Xanthophyllomyces dendrorhous by Schmidt, Isabell, Schewe, Hendrik, Gassel, Sören, Jin, Chao, Buckingham, John, Hümbelin, Markus, Sandmann, Gerhard, Schrader, Jens

“…The oxygenated β-carotene derivative astaxanthin exhibits outstanding colouring, antioxidative and health-promoting properties and is mainly found in the…”
Get full text

P450BM₋₃-catalyzed whole-cell biotransformation of α-pinene with recombinant Escherichia coli in an aqueous-organic two-phase system by Schewe, Hendrik, Holtmann, Dirk, Schrader, Jens

“…A recombinant Escherichia coli BL21 (DE3) strain overexpressing a variant of P450BM₋₃ (V26T/R47F/A74G/F87V/L188K; abbreviated: BL21 (P450BM₋₃ QM))…”
Get full text

High Versatility of IPP and DMAPP Methyltransferases Enables Synthesis of C 6 , C 7 and C 8 Terpenoid Building Blocks by Drummond, Laura, Haque, Parab J, Gu, Binbin, Jung, Julia S, Schewe, Hendrik, Dickschat, Jeroen S, Buchhaupt, Markus

“…The natural substance class of terpenoids covers an extremely wide range of different structures, although their building block repertoire is limited to the C…”
Get full text

High Versatility of IPP and DMAPP Methyltransferases Enables Synthesis of C6, C7 and C8 Terpenoid Building Blocks by Drummond, Laura, Haque, Parab J., Gu, Binbin, Jung, Julia S., Schewe, Hendrik, Dickschat, Jeroen S., Buchhaupt, Markus

“…The natural substance class of terpenoids covers an extremely wide range of different structures, although their building block repertoire is limited to the C5…”
Get full text

Improvement of P450(BM-3) whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli by Schewe, Hendrik, Kaup, Bjoern-Arne, Schrader, Jens

“…Escherichia coli BL21, expressing a quintuple mutant of P450(BM-3), oxyfunctionalizes alpha-pinene in an NADPH-dependent reaction to alpha-pinene oxide,…”
Get full text

Investigation of plasmid-induced growth defect in Pseudomonas putida by Mi, Jia, Sydow, Anne, Schempp, Florence, Becher, Daniela, Schewe, Hendrik, Schrader, Jens, Buchhaupt, Markus

“…•Maintenance of pMiS1 plasmid affects P. putida cell growth.•Newly identified low copy rep mutants of the pBBR1 replicon lead to wildtype-like…”
Get full text

Identification of Fungal Limonene-3-Hydroxylase for Biotechnological Menthol Production by Schempp, Florence M, Strobel, Ingmar, Etschmann, Maria M W, Bierwirth, Elena, Panten, Johannes, Schewe, Hendrik, Schrader, Jens, Buchhaupt, Markus

“…More than 30,000 tons of menthol are produced every year as a flavor and fragrance compound or as a medical component. So far, only extraction from plant…”
Get full text

Biooxidation of monoterpenes with bacterial monooxygenases by Schewe, Hendrik, Mirata, Marco Antonio, Holtmann, Dirk, Schrader, Jens

“…Biotechnological monoterpene oxidation has a considerable economic potential as an alternative route to natural monoterpenoid compounds with desirable…”
Get full text

Efficient hydroxylation of 1,8-cineole with monoterpenoid-resistant recombinant Pseudomonas putida GS1 by Mi, Jia, Schewe, Hendrik, Buchhaupt, Markus, Holtmann, Dirk, Schrader, Jens

“…In this work, monoterpenoid hydroxylation with Pseudomonas putida GS1 and KT2440 were investigated as host strains, and the cytochrome P450 monooxygenase…”
Get full text

Improvement of P450BM₋₃ whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli by Schewe, Hendrik, Kaup, Bjoern-Arne, Schrader, Jens

“…Escherichia coli BL21, expressing a quintuple mutant of P450BM₋₃, oxyfunctionalizes α-pinene in an NADPH-dependent reaction to α-pinene oxide, verbenol, and…”
Get full text

Bioprocess engineering for microbial synthesis and conversion of isoprenoids by Schewe, Hendrik, Mirata, Marco Antonio, Schrader, Jens

“…Isoprenoids represent a natural product class essential to living organisms. Moreover, industrially relevant isoprenoid molecules cover a wide range of…”
Get more information

P450BM-3-catalyzed whole-cell biotransformation of [alpha]-pinene with recombinant Escherichia coli in an aqueous-organic two-phase system by Schewe, Hendrik, Holtmann, Dirk, Schrader, Jens

“…A recombinant Escherichia coli BL21 (DE3) strain overexpressing a variant of P450^sub BM-3^ (V26T/R47F/A74G/F87V/L188K; abbreviated: BL21 (P450^sub BM-3^ QM))…”
Get full text

Coupling of electrochemical and optical measurements in a microtiter plate for the fast development of electro enzymatic processes with P450s by Ley, Claudia, Schewe, Hendrik, Ströhle, Frank W., Ruff, Anne Joelle, Schwaneberg, Ulrich, Schrader, Jens, Holtmann, Dirk

“…•The electrochemical micotiter plate (eMTP) was used for the investigation of an electro enzymatic process.•A P450 BM3 mutein library was screened toward its…”
Get full text

Improvement of P450 sub(BM-3) whole-cell biocatalysis by integrating heterologous cofactor regeneration combining glucose facilitator and dehydrogenase in E. coli by Schewe, Hendrik, Kaup, Bjoern-Arne, Schrader, Jens

“…Escherichia coli BL21, expressing a quintuple mutant of P450 sub(BM-3), oxyfunctionalizes alpha -pinene in an NADPH-dependent reaction to alpha -pinene oxide,…”
Get full text