Search Results - "Scheuermann, Valérie"
-
1
Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans
Published in American journal of respiratory and critical care medicine (01-02-2011)“…Diaphragmatic function is a major determinant of the ability to successfully wean patients from mechanical ventilation (MV). Paradoxically, MV itself results…”
Get full text
Journal Article -
2
Biocompatible modified water as a non-pharmaceutical approach to prevent metabolic syndrome features in obesogenic diet-fed mice
Published in Food and chemical toxicology (01-07-2020)“…The prevalence of metabolic syndrome (MetS), elevating cardiovascular risks, is increasing worldwide, with no available global therapeutic options. The intake…”
Get full text
Journal Article -
3
Diastolic Cardiomyopathy Secondary to Experimentally Induced Exacerbated Emphysema
Published in American journal of respiratory cell and molecular biology (01-08-2023)“…Chronic obstructive pulmonary disease (COPD) is a clinical entity of increasing significance. COPD involves abnormalities of the airways and, in emphysema,…”
Get full text
Journal Article -
4
Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2016)“…Ventilator-induced diaphragmatic dysfunction (VIDD) refers to the diaphragm muscle weakness that occurs following prolonged controlled mechanical ventilation…”
Get full text
Journal Article -
5
ER stress disturbs SR/ER-mitochondria Ca2+ transfer: Implications in Duchenne muscular dystrophy
Published in Biochimica et biophysica acta. Molecular basis of disease (01-09-2017)“…Besides its role in calcium (Ca2+) homeostasis, the sarco-endoplamic reticulum (SR/ER) controls protein folding and is tethered to mitochondria. Under…”
Get full text
Journal Article -
6
Stabilizing Ryanodine Receptors Improves Left Ventricular Function in Juvenile Dogs With Duchenne Muscular Dystrophy
Published in Journal of the American College of Cardiology (14-12-2021)“…Duchenne muscular dystrophy is associated with progressive deterioration in left ventricular (LV) function. The golden retriever muscular dystrophy (GRMD) dog…”
Get full text
Journal Article -
7
Early calcium handling imbalance in pressure overload-induced heart failure with nearly normal left ventricular ejection fraction
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2019)“…Heart failure with preserved ejection fraction (HFpEF) is a common clinical syndrome associated with high morbidity and mortality. Therapeutic options are…”
Get full text
Journal Article -
8
Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F 4t -neuroprostane protects the heart against reperfusion injury
Published in Free radical biology & medicine (01-01-2017)“…Acute myocardial infarction leads to an increase in oxidative stress and lipid peroxidation. 4(RS)-4-F -Neuroprostane (4-F -NeuroP) is a mediator produced by…”
Get full text
Journal Article -
9
Respiratory muscle contractile inactivity induced by mechanical ventilation in piglets leads to leaky ryanodine receptors and diaphragm weakness
Published in Journal of muscle research and cell motility (01-02-2017)“…Respiratory muscle contractile inactivity during mechanical ventilation (MV) induces diaphragm muscle weakness, a condition referred to as ventilator-induced…”
Get full text
Journal Article -
10
Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids
Published in International journal of molecular sciences (11-01-2021)“…Numerous protocols of cardiac differentiation have been established by essentially focusing on specific growth factors on human pluripotent stem cell (hPSC)…”
Get full text
Journal Article -
11
Cardioprotective effect of sonic hedgehog ligand in pig models of ischemia reperfusion
Published in Theranostics (01-01-2020)“…Sonic hedgehog (SHH) signaling pathway is involved in embryonic tissue patterning and development. Our previous work identified, in small rodent model of…”
Get full text
Journal Article -
12
Altered myofilament structure and function in dogs with Duchenne muscular dystrophy cardiomyopathy
Published in Journal of molecular and cellular cardiology (01-01-2018)“…Duchenne Muscular Dystrophy (DMD) is associated with progressive depressed left ventricular (LV) function. However, DMD effects on myofilament structure and…”
Get full text
Journal Article -
13
Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction
Published in Anesthesiology (Philadelphia) (01-09-2012)“…Controlled mechanical ventilation is associated with ventilator-induced diaphragmatic dysfunction, which impedes weaning from mechanical ventilation. To design…”
Get full text
Journal Article -
14
Concomitant systolic and diastolic alterations during chronic hypertension in pig
Published in Journal of molecular and cellular cardiology (01-06-2019)“…The mechanical and cellular relationships between systole and diastole during left ventricular (LV) dysfunction remain to be established. LV…”
Get full text
Journal Article -
15
Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart
Published in International journal of molecular sciences (01-05-2021)“…Duchenne muscular dystrophy (DMD) is a devastating condition shortening the lifespan of young men. DMD patients suffer from age-related dilated cardiomyopathy…”
Get full text
Journal Article -
16
Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury
Published in Free radical biology & medicine (01-01-2017)“…Acute myocardial infarction leads to an increase in oxidative stress and lipid peroxidation. 4(RS)-4-F4t-Neuroprostane (4-F4t-NeuroP) is a mediator produced by…”
Get full text
Journal Article -
17
ER stress disturbs SR/ER-mitochondria Ca 2+ transfer: Implications in Duchenne muscular dystrophy
Published in Biochimica et biophysica acta. Molecular basis of disease (01-09-2017)“…Besides its role in calcium (Ca ) homeostasis, the sarco-endoplamic reticulum (SR/ER) controls protein folding and is tethered to mitochondria. Under…”
Get full text
Journal Article -
18
Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase
Published in Biochimica et biophysica acta (01-05-2015)“…Long chain fatty acids bind to carnitine and form long chain acyl carnitine (LCAC), to enter into the mitochondria. They are oxidized in the mitochondrial…”
Get full text
Journal Article -
19
Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans
Published in American journal of respiratory and critical care medicine (2011)“…Rationale. Diaphragmatic function is a major determinant of the ability to successfully wean patients from mechanical ventilation (MV). Paradoxically, MV…”
Get full text
Journal Article -
20
Early Myocardial Dysfunction and Benefits of Cardiac Treatment in Young X-Linked Duchenne Muscular Dystrophy Mice
Published in Cardiovascular drugs and therapy (01-10-2022)“…Context Duchenne muscular dystrophy (DMD) is associated with a progressive alteration in cardiac function. Objective The aim of this study was to detect early…”
Get full text
Journal Article