Search Results - "Schetz, J. A."

Interactions of the Novel Antipsychotic Aripiprazole (OPC-14597) with Dopamine and Serotonin Receptor Subtypes by Lawler, Cindy P, Prioleau, Cassandra, Lewis, Mechelle M, Mak, Chun, Jiang, Dong, Schetz, John A, Gonzalez, Antonio M, Sibley, David R, Mailman, Richard B

“…OPC-14597 {aripiprazole; 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone} is a novel candidate antipsychotic that has high…”
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Multidisciplinary design optimization of blended-wing-body transport aircraft with distributed propulsion by Leifsson, L., Ko, A., Mason, W.H., Schetz, J.A., Grossman, B., Haftka, R.T.

“…The idea of using distributed propulsion has been suggested with the objective of reducing aircraft noise. This paper investigates the effects of such a system…”
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Distribution and pharmacokinetics of a potent peptide antagonist of parathyroid hormone and parathyroid hormone-related protein in the rat by Schetz, J A, Mayr, C A, Taylor, J E, Rosenblatt, M, Chorev, M, Davis, T P

“…Humoral hypercalcemia of malignancy results from the production by cancer cells of parathyroid hormone related protein that activates receptors in bone…”
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Rapid in vivo metabolism of a methylether derivative of (+/-)-BW373U86: the metabolic fate of [3H]SNC121 in rats by Schetz, J A, Calderon, S N, Bertha, C M, Rice, K, Porreca, F

“…Activation of opioid delta receptors produces antinociception without some of the side-effects associated with activation of mu and kappa receptors…”
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Pharmacology of the high-affinity apamin receptor in rabbit heart by Schetz, J A, Anderson, P A

“…Apamin is a potent blocker of calcium-activated small conductance potassium (SK) channels in neurons, liver, skeletal muscle and ileum smooth muscle, but not…”
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A Reevaluation of the Structure in the Pore Region of Voltage-Activated Cation Channels by Schetz, John A., Peter A. V. Anderson

“…Members of the Voltage-Sensitive Cation Channel (VSCC) superfamily from highly selective voltage-gated pores in excitable membranes. These pores are thought to…”
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New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia aurea by HU, Jin-Feng, SCHETZ, John A., KELLY, Michelle, PENG, Jiang-Nan, ANG, Kenny K. H., FLOTOW, Horst, LEONG, Chung Yan, NG, Siew Bee, BUSS, Antony D., WILKINS, Scott P., HAMANN, Mark T.

“…In addition to the sesquiterpene-phenol aureols (1), 6'-chloroaureol (2), and aureol acetate (3), eight indole alkaloids including the new…”
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Adenosine Receptor Mediates Motility in Human Melanoma Cells by Woodhouse, Elisa C., Amanatullah, Derek F., Schetz, John A., Liotta, Lance A., Stracke, Mary L., Clair, Timothy

“…Cell motility is an essential component of tumor progression and metastasis. A number of factors, both autocrine and paracrine, have been found to influence…”
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Dopamine D2‐Receptor Isoforms Expressed in AtT20 Cells Inhibit Q‐Type High‐Voltage‐Activated Ca2+ Channels via a Membrane‐Delimited Pathway by Wolfe, Shannyn E., Howard, Daniel E., Schetz, John A., Cheng, Caroline J., Webber, Robert, Beatty, Diane M., Chronwall, Bibie M., Morris, Stephen J.

“…: Dopamine D2 receptors both acutely and chronically inhibit high‐voltage‐activated Ca2+ channels (HVA‐CCs). Two alternatively spliced isoforms, D2L (long) and…”
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Pattern recognition metric for comparison of protein structures based on amino acid sequences by Schetz, J A

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AERODYNAMICS OF HIGH-SPEED TRAINS by Schetz, Joseph A

“…This review highlights the differences between the aerodynamics of high-speed trains and other types of transportation vehicles. The emphasis is on modern,…”
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The binding-site crevice of the D4 dopamine receptor is coupled to three distinct sites of allosteric modulation by Schetz, J A, Sibley, D R

“…Most biogenic amine G protein-coupled receptors contain a conserved aspartic acid residue positioned near the intracellular side of the second…”
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Fiber optic pressure/skin friction gage for supersonic flow applications by Pulliam, W, Jones, M, Schetz, JA, Murphy, K

“…A fiber optic skin friction gage has been developed for supersonic flow applications. Experimental results for a Mach 3 2-D flow are presented. Accuracy within…”
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Zinc modulates antagonist interactions with D2-like dopamine receptors through distinct molecular mechanisms by Schetz, J A, Chu, A, Sibley, D R

“…Recently, zinc has been shown to modulate antagonist drug interactions with the D1 dopamine receptor (Schetz and Sibley, 1997) and the dopamine transporter…”
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Zinc Allosterically Modulates Antagonist Binding to Cloned D1 and D2 Dopamine Receptors by Schetz, John A., Sibley, David R.

“…: Cations of various size and charge were used as atomic scale probes of D1 and D2 dopamine receptors. Those cations that perturbed the binding of D1‐ and…”
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A prototypical Sigma-1 receptor antagonist protects against brain ischemia by Schetz, John A, Perez, Evelyn, Liu, Ran, Chen, Shiuhwei, Lee, Ivan, Simpkins, James W

“…Abstract Previous studies indicate that the Sigma-1 ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects the brain from ischemia. Less clear is whether…”
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Tandem sulfur-containing amino acids are epicritical determinants of dopamine D(2) receptor pharmacology by Schetz, J A, Sibley, D R

“…The conserved aspartic acid that is required for ligand binding to the dopamine D(2) receptor is followed by three tandem sulfur-containing amino acids. While…”
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Exploration of structure-antifouling relationships of capsaicin-like compounds that inhibit zebra mussel (Dreissena polymorpha) macrofouling by Angarano, Maj-Britt, McMahon, Robert F., Hawkins, Doyle L., Schetz, John A.

“…Macrofouling of aquatic man-made structures by zebra mussels (Dreissena polymorpha) poses significant economic burdens on commercial freshwater shipping and…”
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Nonconserved residues in the second transmembrane-spanning domain of the D(4) dopamine receptor are molecular determinants of D(4)-selective pharmacology by Schetz, J A, Benjamin, P S, Sibley, D R

“…The molecular determinants that govern selective ligand binding to the rat D(4) dopamine receptor were investigated by substituting D(2) dopamine receptor…”
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Zinc allosterically modulates antagonist binding to cloned D1and D2 dopamine receptors by SCHETZ, J. A, SIBLEY, D. R

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