Search Results - "Schettler, Pamela J"
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Adverse Consequences of Glucocorticoid Medication: Psychological, Cognitive, and Behavioral Effects
Published in The American journal of psychiatry (01-10-2014)“…Glucocorticoids are the most commonly prescribed anti-inflammatory/immunosuppressant medications worldwide. This article highlights the risk of clinically…”
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A double-blind, randomized controlled clinical trial comparing eicosapentaenoic acid versus docosahexaenoic acid for depression
Published in The journal of clinical psychiatry (01-01-2015)“…To compare 2 omega-3 (n-3) preparations enriched with eicosapentaenoic acid (EPA) versus docosahexaenoic acid (DHA) as monotherapy for major depressive…”
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Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders
Published in Journal of affective disorders (01-05-2008)“…Abstract Objective The research literature on psychosocial disability and work in mood disorders has either focused on relatively short-term course, or did not…”
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Six versus twelve weeks of Swedish massage therapy for generalized anxiety disorder: Preliminary findings
Published in Complementary therapies in medicine (01-01-2021)“…Acute treatment of Generalized Anxiety Disorder often requires 3 months or more of care in order to optimize response. As part of an exploratory grant we have…”
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Individuals with depression exhibiting a pro-inflammatory phenotype receiving omega-3 polyunsaturated fatty acids experience improved motivation-related cognitive function: Preliminary results from a randomized controlled trial
Published in Brain, behavior, & immunity. Health (01-10-2023)“…Cognitive impairment related to major depressive disorder (MDD) is highly prevalent, debilitating and is lacking in effective treatments; dysregulated…”
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Long-term symptomatic status of bipolar I vs. bipolar II disorders
Published in The international journal of neuropsychopharmacology (01-06-2003)“…Weekly affective symptom severity and polarity were compared in 135 bipolar I (BP I) and 71 bipolar II (BP II) patients during up to 20 yr of prospective…”
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The distinct temperament profiles of bipolar I, bipolar II and unipolar patients
Published in Journal of affective disorders (01-05-2006)“…Despite a plethora of studies, controversies abound on whether the long-term traits of unipolar and bipolar patients could be differentiated by temperament and…”
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Deficits in Psychological Well‐Being and Quality‐of‐Life in Minor Depression: Implications for DSM‐V
Published in CNS neuroscience & therapeutics (01-08-2010)“…Objective: To examine deficits in psychological well‐being (PWB) and quality‐of‐life (QOL) in minor depressive disorder (Min D). Method: Ninety‐three subjects…”
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Overt irritability/anger in unipolar major depressive episodes: past and current characteristics and implications for long-term course
Published in JAMA psychiatry (Chicago, Ill.) (01-11-2013)“…Although symptoms of irritability or anger are not central to the diagnosis of unipolar major depressive episodes (MDEs), these symptoms have been found, in…”
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Clinical response to EPA supplementation in patients with major depressive disorder is associated with higher plasma concentrations of pro-resolving lipid mediators
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2023)“…Chronic inflammation has been implicated in the pathophysiology of major depressive disorder (MDD). Activating the resolution of inflammation through ω-3 fatty…”
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Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation
Published in Prostaglandins, leukotrienes and essential fatty acids (01-01-2021)“…•EPA supplementation dose-dependently increases EPA-derived lipid mediators.•A daily dose of 4 g EPA is associated with increases in EPA-derived resolvin E2…”
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Massage therapy decreases cancer‐related fatigue: Results from a randomized early phase trial
Published in Cancer (01-02-2018)“…BACKGROUND Cancer‐related fatigue (CRF) is a prevalent and debilitating symptom experienced by cancer survivors, yet treatment options for CRF are limited. In…”
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Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Randomized Dose-Finding Clinical Trial
Published in The journal of clinical psychiatry (01-09-2022)“…Objective: This study compared the impact of 3 eicosapentaenoic acid (EPA) doses versus placebo on inflammatory biomarkers and depressive symptoms. Methods:…”
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A Brief Clinical Tool to Estimate Individual Patients’ Risk of Depressive Relapse Following Remission: Proof of Concept
Published in The American journal of psychiatry (01-11-2016)“…Objective:The authors sought to determine whether symptoms experienced by formerly depressed patients after at least 8 weeks of remission can be used to…”
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Prevalence and clinical significance of subsyndromal manic symptoms, including irritability and psychomotor agitation, during bipolar major depressive episodes
Published in Journal of affective disorders (01-05-2012)“…Abstract Background There is increasing evidence that subsyndromal manic symptoms occur frequently during bipolar major depressive episodes (MDEs) and may be a…”
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A New Empirical Definition of Major Depressive Episode Recovery and Its Positive Impact on Future Course of Illness
Published in The journal of clinical psychiatry (01-08-2016)“…To provide the first head-to-head test of the predictive validity of 2 resolution levels included in the current consensus definition of major depressive…”
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A preliminary descriptive report of the longevity of the effects of Swedish Massage therapy for subjects with Generalized Anxiety Disorder
Published in Journal of bodywork and movement therapies (01-01-2023)“…Generalized Anxiety Disorder (GAD) is a prevalent and costly disorder, and many patients may prefer non-traditional treatment. A proof-of-concept study…”
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Anxiety and Outcome in Bipolar Disorder
Published in The American journal of psychiatry (01-11-2009)“…Objective: Important differences exist between bipolar disorder with and without comorbid anxiety, but little is known about the long-term prognostic…”
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The treatment of minor depression with St. John’s Wort or citalopram: Failure to show benefit over placebo
Published in Journal of psychiatric research (01-07-2011)“…Abstract This paper presents new data addressing two important controversies in psychiatry: the construct of Minor Depression (MinD) and the efficacy of St…”
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The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: a clinical spectrum or distinct disorders?
Published in Journal of affective disorders (2003)“…Background: The present analyses were designed to compare the clinical characteristics and long-term episode course of Bipolar-I and Bipolar-II patients in…”
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