Search Results - "Scherz, T"

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study by Kappos, Ludwig, Fox, Robert J, Wallström, Erik, Akman-Demir, Gulsen, Allen, Alison B, Applebee, Angela M, Balci, Belgin Petek, Barnett, Michael, Bass, Ann, Bejinariu, Mihaela, Bernitsas, Evanthia, Bhan, Virender, Boehringer, Matthias, Bracknies, Vera, Brescia Morra, Vincenzo, Brozman, Miroslav, Calkwood, Jonathan C, Cascione, Mark, Castelnovo, Giovani, Cooper, Joanna A, Corboy, John, Coyle, Patricia K, Craner, Matthew, Cunha, Luis, da Silva, Ana Martins, Deri, Norma H, Edan, Gilles, Elias, Stanton, Estruch, Bonaventura Casanova, Faiss, Juergen, Fedyanin, Alexander S, Fermont, Jiske, Fernandez, Oscar Fernandez, Ferrer, Francisco Coret, Ford, Corey, Gehring, Klaus, Gobbi, Claudio, Grandmaison, Francois, Grimaldi, Luigi Maria Edoardo, Haas, Judith, Harmjanz, Arndt, Herbert, Joseph, Hofmann, Werner E, Huang, Dehui, Huang, DeRen, Hupperts, Raymond, Karussis, Dimitrios, Khabirov, Farit A, Kister, Ilya, Krastev, Georgi, Lassek, Christoph, Laureys, Guy, Lee, Liesly, Li, Hongzeng, Linnebank, Michael, Maeurer, Mathias, Marfia, Girolama Alessandra, Meca-Lallana, Jose, Mihetiu, Ioan Gheorghe, Miller, Aaron E, Montoya, Lilina, Nakatsuji, Yuji, Nicholas, Richard, Nikfekr, Esmaeil, Odinak, Miroslav M, Olsson, Tomas, van Oosten, B W, Oreja-Guevara, Celia, Oschmann, Patrick, Pachner, Andrew, Panczel, Gyula, Pandolfo, Massimo, Pelletier, Jean, Piedrabuena, Raul, Rastenyte, Daiva, Rey, Roberto, Rozsa, Csilla, Rusek, Stanislaw, Saida, Takahiko, Salgado, Antonio Vasco, Sanders, Kalina, Schwab, Matthias, Scott, James, Shafer, Stuart, Shotekov, Penko, Siever, Arno, Sigel, Karl-Otto, Simu, Mihaela, Stangel, Martin, Stourac, Pavel, Tavernarakis, Antonios, Terzi, Murat, Ticmeanu, Marina, Tiel-Wilck, Klaus, Turcani, Peter, Valikovics, Attila, Weiss, Sara, Vermersch, Patrick, Yamamura, Takashi, Zacharias, Alan

“…No treatment has consistently shown efficacy in slowing disability progression in patients with secondary progressive multiple sclerosis (SPMS). We assessed…”
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Circulating nucleases degrade high-molecular-weight cell-free DNA in coronary vessels during acute myocardial infarction by Artner, T, Ondracek, A S, Hofbauer, T M, Scherz, T, Sharma, S, Rinderer, J, Panzenboeck, A, Testori, C, Beitzke, D, Mangold, A, Lang, I M

“…Abstract Introduction Extracellular cell-free DNA (cfDNA) originates from various biological processes, including cell turnover, apoptosis, necrosis, NETosis,…”
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Neutrophil extracellular traps induce MCP-1 release from endothelial cells at the plaque rupture site in acute myocardial infarction by Ondracek, A, Hofbauer, T.M, Mangold, A, Scherz, T, Seidl, V, Lang, I.M

“…Abstract Introduction Leukocyte-mediated inflammation is crucial in acute myocardial infarction (AMI). We recently observed that neutrophil extracellular traps…”
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Malondialdehyde-specific natural IgM inhibit toll-like receptor 4 and peptidyl-arginine deiminase 4-dependent NETosis triggered by coronary extracellular vesicles of myocardial infarction patients by Ondracek, A, Afonyushkin, T, Aszlan, A, Taqi, S, Koller, T, Artner, T, Porsch, F, Sharma, S, Scherz, T, Hofbauer, T M, Ozsvar-Kozma, M, Beitzke, D, Testori, C, Lang, I M, Binder, C J

“…Abstract Background Neutrophil extracellular traps (NETs) are critical mediators of thromboinflammation during acute myocardial infarction (AMI). However,…”
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Natural igm recognizing oxidation-specific epitopes block netosis induced by extracellular vesicles by Ondracek, A.S., Afonyushkin, T., Taqi, S., Hofbauer, T.M., Kozma, M. Ozsvar, Sharma, S., Scherz, T., Beitzke, D., Testori, C., Lang, I.M., Binder, C.J.

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Fibrocytes And Neutrophil Extracellular Traps At The Culprit Lesion Site In Myocardial Infarction: A Role For Monocyte Chemoattractant Protein 1 by Hofbauer, T.M., Mangold, A., Ondracek, A.S., Scherz, T., Seidl, V., Lang, I.M.

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Natural IgM attenuate formation of neutrophil extracellular traps induced by oxidation-specific epitopes in vitro and in vivo by Ondracek, A, Afonyushkin, T, Taqi, S, Aszlan, A, Koller, T, Hofbauer, T M, Ozsvar-Kozma, M, Sharma, S, Scherz, T, Beitzke, D, Testori, C, Lang, I M, Binder, C J

“…Abstract Background Neutrophil extracellular traps (NETs) emerged as important drivers of thrombus formation in acute myocardial infarction (AMI). Therefore,…”
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P152The Q222R deoxyribonuclease I single nucleotide polymorphism is associated with mortality in patients after ST-elevation myocardial infarction by Ondracek, A, Hofbauer, T M, Scherz, T, Mueller, J, Panzenboeck, A, Mangold, A, Lang, I M

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P149Angiotensin-II enhances neutrophil extracellular trap formation in an AT1R and NADPH oxidase-dependent manner by Hofbauer, T M, Scherz, T, Ondracek, A, Mueller, J, Mangold, A, Lang, I M

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P184High platelet activity in hypothermic patients with acute ST-elevation myocardial infarction by Scherz, T, Hofbauer, T, Ondracek, A, Simon, D, Testori, C H, Sterz, F, Mangold, A, Lang, I M

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P572Neutrophil activation and neutrophil extracellular traps in STEMI patients treated with therapeutic hypothermia by Mangold, A, Scherz, T, Hofbauer, T, Ondracek, A, Simon, D, Testori, C, Sterz, F, Lang, I M

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3397The Q222R deoxyribonuclease 1 single nucleotide polymorphism independently predicts mortality in patients with coronary artery disease after ST-elevation myocardial infarction by Hofbauer, T M, Scherz, T, Ondracek, A, Mueller, J, Panzenboeck, A, Feist, C, Kascha, L, Frueh, A, Horvat Menih, I, Kuehn, S, Mangold, A, Lang, I M

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P272Protein tyrosine phosphatase non receptor type 22 (PTPN22) function impacts neutrophil extracellular trap formation by Kascha, L, Hofbauer, T, Winter, M P, Panzenboeck, A, Distelmaier, K, Scherz, T, Ondracek, A, Feist, C, Mangold, A, Lang, I M

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Long-term Efficacy and Safety of Ponesimod, an oral S1P1 Receptor Modulator: Results from Randomized Phase II Core and Extension Studies in Relapsing-Remitting Multiple Sclerosis (1752) by Freedman, Mark S., Pozzilli, Carlo, Havrdova, Eva Kubala, Coyle, Patricia K., Lemle, Alexandre, Burcklen, Michel, Larbalestier, Anna, Hennessy, Brian, Scherz, Tatiana, Vaclavkova, Andrea, Olsson, Tomas

“…Abstract only…”
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C59 BIOMARKERS AND PROGNOSTIC FACTORS IN PULMONARY HYPERTENSION: Parenteral Treprostinil Induces A Phenotypic Shift Of Circulating Monocyte Subsets by Hofbauer, T, Mangold, A, Scherz, T, Simon, D, Sadushi-Kolici, R, Lang, I M

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P728CD4+CD28 null T cells are enriched at the culprit lesion site in STE-ACS and promote NET production by Scherz, T, Mangold, A, Hofbauer, T, Adlbrecht, C, Lang, IM

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C54 TREATMENT OF PULMONARY HYPERTENSION: Parenteral Treprostinil Leads To A Shift In The Myeloid To Plasmacytoid Dendritic Cell Ratio by Hofbauer, T, Mangold, A, Scherz, T, Sadushi-Kolici, R, Lang, I

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C54 TREATMENT OF PULMONARY HYPERTENSION: Parenteral Treprostinil Inhibits The Recruitment Of Circulating Fibrocytes And Enhances Bmprii Expression by Hofbauer, T, Mangold, A, Scherz, T, Sadushi-Kolici, R, Lang, I

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CD4+CD28null T-cell enrichment at the culprit lesion site in STE-ACS by Mangold, A., Scherz, T., Falkinger, A., Hofbauer, T., Adlbrecht, C., Lang, I. M.

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P726Coronary NET burden and DNase activity in ST-elevation acute coronary syndrome are predictors of infarct size by Mangold, A, Scherz, T, Alias, S, Hofbauer, T, Jakowitsch, J, Bangert, C, Pfaffenberger, S, Winter, MP, Preissner, KT, Lang, IM

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