Search Results - "Scherwitzl, Iris"
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The alteration of NK cells phenotypes related to the functions and dengue disease outcomes
Published in Virus research (01-07-2024)“…•The NKp30 receptor's expression on activated NK cells is more pronounced in DF patients than in DHF patients, suggesting a potential role of this receptor in…”
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2
Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody
Published in Journal for immunotherapy of cancer (15-07-2019)“…Limitations to current therapies for treating non-Hodgkin B cell lymphoma include relapse, toxicity and high cost. Thus, there remains a need for novel…”
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Journal Article -
3
Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors
Published in Molecular therapy. Oncolytics (26-06-2020)“…Despite remarkable responses to cancer immunotherapy in a subset of patients, many patients remain resistant to therapies. It is now clear that elevated levels…”
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4
Systemically Administered Sindbis Virus in Combination with Immune Checkpoint Blockade Induces Curative Anti-tumor Immunity
Published in Molecular therapy. Oncolytics (29-06-2018)“…Oncolytic viruses represent a promising form of cancer immunotherapy. We investigated the potential of Sindbis virus (SV) for the treatment of solid tumors…”
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5
Recent advances in human flavivirus vaccines
Published in Current opinion in virology (01-04-2017)“…•No WNV and ZIKV vaccines are available for human use.•Some WNV vaccine candidates show promising results in phase II clinical trials.•First licensed DENV…”
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6
MAIT cells are activated during human viral infections
Published in Nature communications (23-06-2016)“…Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize bacterial ligands. Here, we demonstrate that MAIT cells are also activated…”
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7
The role of genomic location and flanking 3′UTR in the generation of functional levels of variant surface glycoprotein in Trypanosoma brucei
Published in Molecular microbiology (01-11-2017)“…Summary Trypanosoma brucei faces relentless immune attack in the mammalian bloodstream, where it is protected by an essential coat of Variant Surface…”
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Journal Article -
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The role of genomic location and flanking 3'UTR in the generation of functional levels of variant surface glycoprotein in Trypanosoma brucei
Published in Molecular microbiology (01-11-2017)“…Trypanosoma brucei faces relentless immune attack in the mammalian bloodstream, where it is protected by an essential coat of Variant Surface Glycoprotein…”
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Journal Article -
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The influence of mait cells and host genomic risk factors on dengue infection
Published 01-01-2016“…Dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually. The clinical spectrum of dengue disease is…”
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Dissertation