Search Results - "Scherrer, Urs"

Sleep apnoea and pulmonary hypertension in high-altitude dwellers: more than an association? by Scherrer, Urs, Verges, Samuel

“…Increased pulmonary arterial pressure (PAP) is a hallmark of high-altitude exposure and, if exaggerated, may be associated with morbidity and mortality. High…”
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Systemic and Pulmonary Vascular Dysfunction in Children Conceived by Assisted Reproductive Technologies by SCHERRER, Urs, RIMOLDI, Stefano F, SARTORI, Claudio, REXHAJ, Emrush, STUBER, Thomas, DUPLAIN, Herve, GARCIN, Sophie, DE MARCHI, Stefano F, NICOD, Pascal, GERMOND, Marc, ALLEMANN, Yves

“…Assisted reproductive technology (ART) involves the manipulation of early embryos at a time when they may be particularly vulnerable to external disturbances…”
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Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span by Rexhaj, Emrush, Paoloni-Giacobino, Ariane, Rimoldi, Stefano F, Fuster, Daniel G, Anderegg, Manuel, Somm, Emmanuel, Bouillet, Elisa, Allemann, Yves, Sartori, Claudio, Scherrer, Urs

“…Children conceived by assisted reproductive technologies (ART) display a level of vascular dysfunction similar to that seen in children of mothers with…”
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Melatonin Improves Glucose Homeostasis and Endothelial Vascular Function in High-Fat Diet-Fed Insulin-Resistant Mice by Sartori, Claudio, Dessen, Pierre, Mathieu, Caroline, Monney, Anita, Bloch, Jonathan, Nicod, Pascal, Scherrer, Urs, Duplain, Hervé

“…Obesity and insulin resistance represent a problem of utmost clinical significance worldwide. Insulin-resistant states are characterized by the inability of…”
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Acute and Chronic Altitude-Induced Cognitive Dysfunction in Children and Adolescents by Rimoldi, Stefano F., MD, Rexhaj, Emrush, MD, Duplain, Hervé, MD, Urben, Sébastien, MD, Billieux, Joël, MD, Allemann, Yves, MD, Romero, Catherine, RN, Ayaviri, Alejandro, MD, Salinas, Carlos, MD, Villena, Mercedes, MD, Scherrer, Urs, MD, Sartori, Claudio, MD

“…Objective To assess whether exposure to high altitude induces cognitive dysfunction in young healthy European children and adolescents during acute, short-term…”
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Increased Arterial Responsiveness to Angiotensin II in Mice Conceived by Assisted Reproductive Technologies by Meister, Theo Arthur, Soria, Rodrigo, Dogar, Afzal, Messerli, Franz H., Paoloni-Giacobino, Ariane, Stenz, Ludwig, Scherrer, Urs, Sartori, Claudio, Rexhaj, Emrush

“…Since the first report in 1978, the number of individuals conceived by Assisted Reproductive Technologies (ART) has grown incessantly. In parallel, with the…”
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Fetal programming of pulmonary vascular dysfunction in mice: role of epigenetic mechanisms by Rexhaj, Emrush, Bloch, Jonathan, Jayet, Pierre-Yves, Rimoldi, Stefano F, Dessen, Pierre, Mathieu, Caroline, Tolsa, Jean-François, Nicod, Pascal, Scherrer, Urs, Sartori, Claudio

“…Insults during the fetal period predispose the offspring to systemic cardiovascular disease, but little is known about the pulmonary circulation and the…”
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Oxidative-Nitrosative Stress and Systemic Vascular Function in Highlanders With and Without Exaggerated Hypoxemia by Bailey, Damian M., PhD, Rimoldi, Stefano F., MD, Rexhaj, Emrush, MD, Pratali, Lorenza, MD, PhD, Salinas Salmòn, Carlos, MD, Villena, Mercedes, MD, McEneny, Jane, PhD, Young, Ian S., MD, Nicod, Pascal, MD, Allemann, Yves, MD, Scherrer, Urs, MD, Sartori, Claudio, MD

“…Background Acute exposure to high altitude stimulates free radical formation in lowlanders, yet whether this persists during chronic exposure in healthy,…”
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Sleep-Disordered Breathing and Vascular Function in Patients With Chronic Mountain Sickness and Healthy High-Altitude Dwellers by Rexhaj, Emrush, MD, Rimoldi, Stefano F., MD, Pratali, Lorenza, MD, Brenner, Roman, MD, Andries, Daniela, BS, Soria, Rodrigo, MD, Salinas, Carlos, MD, Villena, Mercedes, MD, Romero, Catherine, BS, Allemann, Yves, MD, Lovis, Alban, MD, Heinzer, Raphaël, MD, Sartori, Claudio, MD, Scherrer, Urs, MD

“…Background Chronic mountain sickness (CMS) is often associated with vascular dysfunction, but the underlying mechanism is unknown. Sleep-disordered breathing…”
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Systemic Vascular Dysfunction in Patients With Chronic Mountain Sickness by Rimoldi, Stefano F., MD, Rexhaj, Emrush, MD, Pratali, Lorenza, MD, PhD, Bailey, Damian M., PhD, Hutter, Damian, MD, Faita, Francesco, PhD, Salinas Salmòn, Carlos, MD, Villena, Mercedes, MD, Nicod, Pascal, MD, Allemann, Yves, MD, Scherrer, Urs, MD, Sartori, Claudio, MD

“…Background Chronic mountain sickness (CMS) is a major public health problem characterized by exaggerated hypoxemia and erythrocytosis. In more advanced stages,…”
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Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice by Deisl, Christine, Anderegg, Manuel, Albano, Giuseppe, Lüscher, Benjamin P, Cerny, David, Soria, Rodrigo, Bouillet, Elisa, Rimoldi, Stefano, Scherrer, Urs, Fuster, Daniel G

“…We previously demonstrated that the sodium/hydrogen exchanger NHA2, also known as NHEDC2 or SLC9B2, is critical for insulin secretion by β-cells. To gain more…”
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Efficacy and Safety of Calcium Channel Blocker/Diuretics Combination Therapy in Hypertensive Patients: A Meta‐Analysis by Rimoldi, Stefano F., Messerli, Franz H., Chavez, Patricia, Stefanini, Giulio G., Scherrer, Urs

“…Although recent guidelines recommend the combination of calcium channel blockers (CCBs) and thiazide (‐like) diuretics, this combination is not widely used in…”
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Economy Class Syndrome, patent foramen ovale and stroke by Messerli, Franz H., MD, Rimoldi, Stefano F., MD, Scherrer, Urs, MD

“…Contrary to the aforementioned statement, it is likely that air travel was indeed the triggering event in the patient under discussion, leading to increased…”
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Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis by Ming, Xiu‐Fen, Rajapakse, Angana G., Yepuri, Gautham, Xiong, Yuyan, Carvas, João M., Ruffieux, Jean, Scerri, Isabelle, Wu, Zongsong, Popp, Katja, Li, Jianhui, Sartori, Claudio, Scherrer, Urs, Kwak, Brenda R., Montani, Jean‐Pierre, Yang, Zhihong

“…Background Macrophage‐mediated chronic inflammation is mechanistically linked to insulin resistance and atherosclerosis. Although arginase I is considered…”
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Vascular dysfunction in children conceived by assisted reproductive technologies: underlying mechanisms and future implications by Rimoldi, Stefano F, Sartori, Claudio, Rexhaj, Emrush, Cerny, David, Von Arx, Robert, Soria, Rodrigo, Germond, Marc, Allemann, Yves, Scherrer, Urs

“…Epidemiological studies in humans have demonstrated a relationship between pathological events during fetal development and increased cardiovascular risk later…”
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Endothelial Nitric Oxide Synthase (eNOS) Knockout Mice Have Defective Mitochondrial β-Oxidation by LE GOUILL, Eric, JIMENEZ, Maria, BINNERT, Christophe, JAYET, Pierre-Yves, THALMANN, Sebastien, NICOD, Pascal, SCHERRER, Urs, VOLLENWEIDER, Peter

“…Endothelial Nitric Oxide Synthase (eNOS) Knockout Mice Have Defective Mitochondrial β-Oxidation Eric Le Gouill 1 , Maria Jimenez 2 , Christophe Binnert 3 ,…”
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Anatomical Eligibility of the Renal Vasculature for Catheter-Based Renal Denervation in Hypertensive Patients by Rimoldi, Stefano F., MD, Scheidegger, Niklaus, BSc, Scherrer, Urs, MD, Farese, Stefan, MD, Rexhaj, Emrush, MD, Moschovitis, Aris, MD, Windecker, Stephan, MD, Meier, Bernhard, MD, Allemann, Yves, MD

“…Objectives This study sought to determine the vascular anatomical eligibility for catheter-based renal artery denervation (RDN) in hypertensive patients…”
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Enhanced expression of three monocarboxylate transporter isoforms in the brain of obese mice by Pierre, Karin, Parent, Annabelle, Jayet, Pierre‐Yves, Halestrap, Andrew P., Scherrer, Urs, Pellerin, Luc

“…Monocarboxylate transporters (MCTs) are membrane carriers for lactate and ketone bodies. Three isoforms, MCT1, MCT2 and MCT4, have been described in the…”
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RV Contractility and Exercise-Induced Pulmonary Hypertension in Chronic Mountain Sickness by Pratali, Lorenza, MD, PhD, Allemann, Yves, MD, Rimoldi, Stefano F., MD, Faita, Francesco, MSc, Hutter, Damian, MD, Rexhaj, Emrush, MD, Brenner, Roman, MD, Bailey, Damian M., BSc, Sartori, Claudio, MD, Salmon, Carlos Salinas, MD, Villena, Mercedes, MD, Scherrer, Urs, MD, Picano, Eugenio, MD, PhD, Sicari, Rosa, MD, PhD

“…Objectives The aim of this study was to evaluate right ventricular (RV) and left ventricular function and pulmonary circulation in chronic mountain sickness…”
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Exaggerated Pulmonary Hypertension and Right Ventricular Dysfunction in High-Altitude Dwellers With Patent Foramen Ovale by Brenner, Roman, MD, Pratali, Lorenza, MD, Rimoldi, Stefano F., MD, Murillo Jauregui, Carla Ximena, MD, Soria, Rodrigo, MD, Rexhaj, Emrush, MD, Salinas Salmón, Carlos, MD, Villena, Mercedes, MD, Romero, Catherine, BS, Sartori, Claudio, MD, Allemann, Yves, MD, Scherrer, Urs, MD

“…Abstract BACKGROUND: There is considerable interindividual variability in pulmonary artery pressure among high-altitude (HA) dwellers, but the underlying…”
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